Results 111 to 120 of about 2,022 (185)

Immune Regulation and Disulfidptosis in Atherosclerosis Influence Disease Progression and Therapy

Biomedicines
Background: Atherosclerosis is a progressive and complex vascular pathology characterized by cellular heterogeneity, metabolic dysregulation, and chronic inflammation. Despite extensive research, the intricate molecular mechanisms underlying its development and progression remain incompletely understood.
Lu, Wei, Zhang, Zhidong, Qiao, Gang, Zou, Gangqiang, Li, Guangfeng   +4 more
openaire   +3 more sources

Novel insights of disulfidptosis-mediated immune microenvironment regulation in atherosclerosis based on bioinformatics analyses

Atherosclerosis (AS) is the leading cause of coronary heart disease, which is the primary cause of death worldwide. Recent studies have identified disulfidptosis as a new type of cell death that may be involved in onset and development of many diseases ...
Zheng Jin, J. F. Fang, Junfeng Fang, Junlong Li, Wei Wu, Huanyi Zhao   +5 more
core   +1 more source

Disulfidptosis: a novel gene-based signature predicts prognosis and immunotherapy efficacy of pancreatic adenocarcinoma

Discover Oncology
Disulfidptosis, a novel form of disulfide stress-induced cell death involved in tumor progression, hasn’t be well defined the function in tumor progression.
Jingyang Yin, Jian Li, Huaizhi Wang
doaj   +1 more source

Image_1_Integrative analysis of disulfidptosis and immune microenvironment in hepatocellular carcinoma: a putative model and immunotherapeutic strategies.tif

BackgroundHepatocellular carcinoma (HCC) is a malignant tumor with a high rate of recurrence and m metastasis that does not respond well to current therapies and has a very poor prognosis.
Peifeng Ke (6855746), Junhao Liu (9250731), Jianfan Wen (4987586), Zengxin Ma (14498550), Yifeng He (563263), Siliang Chen (9101296), Qiaolan Yang (5877050), Juan Duan (144000), Ti Yang (16027271), Jiashun Lei (17722641), Fang Liu (13271), Xiancheng Zeng (470954)   +11 more
core   +1 more source

Disulfidptosis and androgenic cancers: from molecular mechanisms to clinical applications and future translational research

Disulfidptosis, a newly discovered form of programmed cell death, has garnered significant attention in tumor biology and reproductive system research in recent years, particularly demonstrating importance in urological cancer studies.
Li, Qiming, Wang, Xueyang, Xing, Xiping, Zhao, Juan, Zhao, Weiwei, Chang, Jiaqing   +5 more
core   +1 more source

Ultrasound-responsive nanobubble-mediated sonodynamic therapy sensitizes disulfidptosis in the treatment of liver hepatocellular carcinoma

Disulfidptosis, a newly identified regulated cell death, is linked to tumor progression, particularly in cancers with elevated SLC7A11 expression. This study investigates SLC7A11 expression in liver hepatocellular carcinoma (LIHC) and evaluates the ...
Xin Lin, Gang Hou, Shoufeng Wang, Chen Huang, Yucao Sun, Zhiguang Wu, Liwen Deng, Xi Wang, Xiaohui Yan, Jiayue Qiu, Tianhong Zhang, Haitao Shang, Wen Cheng, Yichi Chen, Bolin Wu, Nanxing Li   +15 more
core   +1 more source

Disulfidptosis: molecular mechanisms and therapeutic targets. [PDF]

Signal Transduct Target Ther
Wang C, Zhou J, Jin B, Li G, Zhang L, Tian X, Fan Z.   +6 more
europepmc   +1 more source

Integrated bioinformatic analysis of immune infiltration and disulfidptosis related gene subgroups in type A aortic dissection

Type A aortic dissection (TAAD) is a lethal cardiovascular disease characterized by the separation of the layers within the aortic wall. The underlying pathological mechanisms of TAAD requires further elucidation to develop effective prevention and ...
Anqi Bi, Xinpeng Ge, Kexiang Liu, Chengwen Wang, Zhicheng Zhu, Zhenzhu Zhang, Duo Wang, Haoyue Liu, Mixia Li, Chenguang Gao, Xue Tian   +10 more
core   +1 more source

Disulfidptosis in heart failure: an emerging mechanism awaiting exploration. [PDF]

Front Cardiovasc Med
Ding S, Zang Y, Li Y, Zhang W, Liu Z, Liu C, Wang Q, Zhu L, Ji K.   +8 more
europepmc   +1 more source

Unveiling Disulfidptosis and Cuproptosis Vulnerabilities in Pterygium: A Transcriptomic Analysis and In-Silico Drug Repurposing Strategy. [PDF]

Genes (Basel)
Sarıkaya İ, Kılıç R.
europepmc   +1 more source