Results 11 to 20 of about 2,022 (185)
Disulfidptosis: a new target for metabolic cancer therapy
Journal of Experimental & Clinical Cancer Research, 2023 Altered metabolism is a hallmark of cancer and presents a vulnerability that can be exploited in cancer treatment. Regulated cell death (RCD) plays a crucial role in cancer metabolic therapy.
Peijie Zheng +3 more
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Pan-cancer landscape of disulfidptosis across human tumors
HeliyonObjective: Disulfidptosis is a newly discovered disulfide stress-induced cell death form. Clinical significance and biological mechanisms of disulfidptosis in human cancers need to be further elucidated.
Kun Fang +4 more
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Inducing disulfidptosis in tumors:potential pathways and significance
MedCommRegulated cell death (RCD) is crucial for the elimination of abnormal cells. In recent years, strategies aimed at inducing RCD, particularly apoptosis, have become increasingly important in cancer therapy.
Tao Mi +4 more
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Current Issues in Molecular Biology, 2023 Disulfidptosis is a newly discovered cellular programmed cell death mode. Presently, a considerable number of genes related to disulfidptosis remain undiscovered, and its significance in hepatocellular carcinoma remains unrevealed.
Linghao Ni +4 more
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Identification of disulfidptosis-related genes and subgroups in Alzheimer’s disease [PDF]
Frontiers in Aging Neuroscience, 2023 BackgroundAlzheimer’s disease (AD), a common neurological disorder, has no effective treatment due to its complex pathogenesis. Disulfidptosis, a newly discovered type of cell death, seems to be closely related to the occurrence of various diseases. In this study, through bioinformatics analysis, the expression and function of disulfidptosis-related ...
Shijia Ma, Dan Wang, Daojun Xie
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Disulfidptosis in tumor progression
Cell Death DiscoveryAbstract Disulfidptosis, a regulated cell death modality driven by the cystine transporter solute carrier family 7 member 11 (SLC7A11), is characterized by actin cytoskeleton collapse under glucose starvation. This review systematically elucidates the pivotal role of disulfidptosis in tumor metabolic reprogramming, with a focus on its ...
Senlin Wan +10 more
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Disulfidptosis-associated lncRNAs predict breast cancer subtypes
Scientific Reports, 2023 Abstract Background Disulfidptosis is a newly discovered mode of cell death. However, its relationship with breast cancer subtypes remains unclear. In this study, we aimed to construct a disulfidptosis-associated breast cancer subtype prediction model.
Qing Xia +8 more
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Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma
Cancer Cell InternationalPurpose Metabolic reprogramming is a hallmark of cancer and plays a key role in precision oncology treatment. Long non-coding RNAs (lncRNAs) regulate cancer cell behavior, including metabolism.
Hongfei Yao +3 more
doaj +2 more sources
Cancer Cell InternationalBackground The evolving molecular portrait of acute myeloid leukemia (AML) has exposed previously unrecognized cell death programs that fuel disease progression and treatment resistance—uncovering untapped therapeutic potential. Recent work has uncovered
Yichen Lei +3 more
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Biology DirectBackground Limited supply of certain nutrients and deregulation of nucleus pulposus (NP) plays a key role in the pathogenesis of intervertebral disc degeneration (IVDD).
Shaobo Wu +6 more
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