Results 81 to 90 of about 1,487 (157)

Establishment of prognostic risk model related to disulfidptosis and immune infiltration in hepatocellular carcinoma

Heliyon
Background: Disulfidptosis is a newly discovered type of cell death. We aim to identify hub genes associated with both disulfidptosis and immune infiltration in hepatocellular carcinoma (HCC) patients, and to develop an individualized risk prediction ...
Zhe Xu, Chong Pang, Xundi Xu
doaj   +1 more source

Classification and functional analysis of disulfidptosis‐associated genes in sepsis

Journal of Cellular and Molecular Medicine
AbstractSepsis represents a critical condition characterized by multiple‐organ dysfunction resulting from inflammatory response to infection. Disulfidptosis is a newly identified type of programmed cell death that is intimately associated with the actin cytoskeleton collapse caused by glucose starvation and disulfide stress, but its role in sepsis is ...
Simeng He, Xiangxin Zhang, Zichen Wang, Qingju Zhang, Yu Yao, Jiaojiao Pang, Yuguo Chen   +6 more
openaire   +2 more sources

The characteristics and functional significance of disulfidptosis-related genes in head and neck squamous cell carcinoma

Discover Oncology
Disulfidptosis is a newfound programmed cell death (PCD) mode characterized by disulfide stress. Nevertheless, the characteristics and functional significance of disulfidptosis-related genes in head and neck squamous cell carcinoma (HNSCC) are still ...
Haiqian Zhu, Chifeng Zhao, Haoran Zhu, Xuhui Xu, Conglin Hu, Zhenxing Zhang   +5 more
doaj   +1 more source

Identification of RPL4 as a biomarker associated with disulfidptosis and arachidonic acid metabolism in breast cancer

Discover Oncology
Objective Disulfidptosis is a recently discovered mechanism of cell death caused by disulfide stress. Arachidonic acid metabolism (AAM) is one of the metabolic mechanisms of polyunsaturated fatty acids. However, few studies have explored the relationship
Tao Yan, Bolin Yu, Fengyuan Qian, Lin Fang, Yuanyuan Zhao, Danrong Ye   +5 more
doaj   +1 more source

Disulfidptosis-Associated lncRNAs are Potential Biomarkers for Predicting Immune Response and Prognosis Within Individuals Diagnosed with Hepatocellular Carcinoma

Hepatic Medicine: Evidence and Research, 2023
Qian Wei,1,2,* Yu-Chao Hou,3,* Fei-Fei Mao,4,* Jin-Kai Feng,2 Xu Wang,3 Shu-Qun Cheng1,2,* 1The First Clinical Medicine School, Guangdong Pharmaceutical University, Guangzhou, People’s Republic of China; 2Department of Hepatic Surgery VI,
Wei Q, Hou YC, Mao FF, Feng JK, Wang X, Cheng SQ   +5 more
doaj  

Provoking tumor disulfidptosis by single-atom nanozyme via regulating cellular energy supply and reducing power

Nature Communications
Disulfidptosis, a recently identified form of programmed cell death, is initiated by depletion of endogenous nicotinamide adenine dinucleotide phosphate (NADPH) under glucose starvation.
Wenxin Yu, Duo Jin, Yajie Zhang, Shenghu Wang, Jiaji Yu, Manman Liu, Yi Dai, Yichen Yin, Junjie Cheng, Yangzhong Liu   +9 more
doaj   +1 more source

Disulfidptosis: a novel cell death modality induced by actin cytoskeleton collapse and a promising target for cancer therapeutics

Cell Communication and Signaling
Disulfidptosis is a novel discovered form of programmed cell death (PCD) that diverges from apoptosis, necroptosis, ferroptosis, and cuproptosis, stemming from disulfide stress-induced cytoskeletal collapse.
Tianyi Li, Ying Song, Lijuan Wei, Xiangyi Song, Ruifeng Duan   +4 more
doaj   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science
Disulfidptosis, a novel form of regulated cell death, involves cytoskeletal collapse due to excessive disulfide bond formation, linking metabolism and reactive oxygen species to potential cancer therapy targets.
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
doaj   +1 more source

Identification and validation of a disulfidptosis-related genes prognostic signature in lung adenocarcinoma

Heliyon
Disulfidptosis, a newly revealed form of cell death, regulated by numerous genes that has been recently identified. The exact role of disulfidptosis in lung adenocarcinoma (LUAD) still uncertain.
Yanpeng Zhang, Jingyang Sun, Meng Li, Liren Hou, Zhiyu Wang, Huanhuan Dong, Wenjun Xu, Rongxuan Jiang, Yuhan Geng, Chungen Guan, Zijiang Zhu, Hongyi Wang, Qiuyu Gong, Guangjian Zhang   +13 more
doaj   +1 more source

PPARγ Antagonists Exhibit Antitumor Effects by Regulating Ferroptosis and Disulfidptosis

Biomolecules
Oral squamous cell carcinoma (OSCC) stands as a prevalent subtype of head and neck squamous cell carcinoma, leading to disease recurrence and low survival rates. PPARγ, a ligand-dependent nuclear transcription factor, holds significance in tumor development. However, the role of PPARγ in the development of OSCC has not been fully elucidated.
Shiyu Zhang, Ying Wang, Junjie Gu, Yang Yang, Jing Liang, Yimei Wang, Ning Ji, Ming Liu, Yingxin Zhang, Silu Sun, Qianming Chen, Jing Li   +11 more
openaire   +3 more sources