Results 81 to 90 of about 2,022 (185)

Autophagic flux inhibition potentiates disulfidptosis susceptibility in human hepatocellular carcinoma

Disulfidptosis is a newly recognized form of non-classical cell death, characterized by the abnormal accumulation of disulfide bonds and the collapse of the cytoskeleton.
Yaping Zhao, Fanpu Ji, Lin Li, Xinyan Li, Yinggang Zhang, Enrui Xie, Pengfei Liu, Ying Guo, Yetong Feng, Mengjiao Shi, Jiayi Xu, Liangwen Yan, Rongrong Liu, Xu Gao, Gang Wang, Kailing Hu, Hong Wang   +16 more
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Table3_Identification and validation of disulfidptosis-associated molecular clusters in non-alcoholic fatty liver disease.XLS

, 2023
Objective: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in the world, and its pathogenesis is not fully understood.
Kai Yang, Zhichao Dong, Chang Liu, Zihao Guo (420184), Zhihao Fang, Zhichao Dong (1580200), Chang Liu (35901), Zihao Guo, Changxu Liu, Zhihao Fang (9857225), Xiaoxiao Yu, Kai Yang (73590), Xiaoxiao Yu (1444810), Changxu Liu (1440307)   +13 more
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Classification and functional analysis of disulfidptosis‐associated genes in sepsis

Journal of Cellular and Molecular Medicine
AbstractSepsis represents a critical condition characterized by multiple‐organ dysfunction resulting from inflammatory response to infection. Disulfidptosis is a newly identified type of programmed cell death that is intimately associated with the actin cytoskeleton collapse caused by glucose starvation and disulfide stress, but its role in sepsis is ...
Simeng He, Xiangxin Zhang, Zichen Wang, Qingju Zhang, Yu Yao, Jiaojiao Pang, Yuguo Chen   +6 more
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Disulfidptosis contributes to rotenone-induced dopaminergic neuron damage

Neural Regeneration Research
Parkinson's disease is a neurodegenerative disorder whose pathogenesis remains incompletely understood. Rotenone exposure is reportedly associated with Parkinson's disease. In addition, disulfidptosis is a newly identified form of cell death. Interestingly, an analysis of the Gene Expression Omnibus Parkinson's disease database indicated that ...
Wenqi Ye, Qifu Zhang, Wei Ge, Haoyin Liu, Yaohui Shan, Feng Ye, Xiaogang Wang, Yuanpeng Zhao, Guorong Dan, Mingliang Chen, Yan Sai   +10 more
openaire   +2 more sources

The involvement of lncRNA EMSLR in the disulfidptosis and progression of endometrial carcinoma

Cancer Gene Therapy
The incidence of endometrial cancer (EC) continues to rise. Disulfidptosis, a novel form of cell death, may represent a potential therapeutic target in EC. Through bioinformatic analysis of The Cancer Genome Atlas (TCGA) database, E2F1 mRNA-stabilizing lncRNA (EMSLR) was identified as a lncRNA related to disulfidptosis in EC.
Yixuan Sun, Ruiwen Wang, Xinzhu Li, Wanzhen Zhou, Huixian Huang, Yang Zhou, Xiaolu Zhu, Yifan Yin, Yincheng Teng   +8 more
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Identification of Disulfidptosis-Related Genes and Molecular Subgroups in Rheumatoid Arthritis for Diagnostic Model and Patient Stratification [PDF]

Xinyi Liu,1 Siyao Wang,2 Xinru Du,1 Yulu Wang,3 Lingfei Mo,1 Hanchao Li,1 Zechao Qu,4 Xiaohao Wang,4 Jian Sun,5 Yuanyuan Li,1 Jing Wang1 1Department of Rheumatology and Immunology, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s ...
Liu X, Li H, Li Y, Wang S, Qu Z, Du X, Mo L, Wang X, Wang Y, Wang J, Sun J   +10 more
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Disulfidptosis signature predicts immune microenvironment and prognosis of gastric cancer

Biology Direct
Background Disulfidptosis is a newly identified mechanism of cell death triggered by disulfide stress. Thus, gaining a comprehensive understanding of the disulfidptosis signature present in gastric cancer (GC) could greatly enhance the development of ...
Zitao Liu, Liang Sun, Wenjie Zhu, Jinfeng Zhu, Changlei Wu, Xingyu Peng, Huakai Tian, Chao Huang, Zhengming Zhu   +8 more
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Integrative analysis of disulfidptosis and immune microenvironment in hepatocellular carcinoma: a putative model and immunotherapeutic strategies [PDF]

BackgroundHepatocellular carcinoma (HCC) is a malignant tumor with a high rate of recurrence and m metastasis that does not respond well to current therapies and has a very poor prognosis.
Juan Duan, Qiaolan Yang, Fang Liu, Junhao Liu, Ti Yang, Jiashun Lei, Jianfan Wen, Yifeng He, Xiancheng Zeng, Siliang Chen, Zengxin Ma, Peifeng Ke   +11 more
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Table1_A disulfidptosis-related lncRNA prognostic model to predict survival and response to immunotherapy in lung adenocarcinoma.XLSX

, 2023
Background: Lung adenocarcinoma (LUAD) is the major subtype of lung cancer and has a poor prognosis. Disulfidptosis is a novel regulated cell death form characterized by aberrant disulfide stress and actin network collapse.
Tao Zhu (118644), Jian-Yan Pan (17037837), Hai-Bo Zhang (456173)   +2 more
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DataSheet1_A novel disulfidptosis-associated expression pattern in breast cancer based on machine learning.docx

, 2023
Background: Breast cancer (BC), the leading cause of cancer-related deaths among women, remains a serious threat to human health worldwide. The biological function and prognostic value of disulfidptosis as a novel strategy for BC treatment via induction ...
Jialin Chen (451414), Weibin Lian (11705322), Debo Chen (10589000), Xianqiang Du (10588991), Chengye Hong (16465320), Liangqiang Li (13172400), Zhitang Wang (10588997)   +6 more
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