Results 11 to 20 of about 9,669 (211)
Frontiers in Microbiology, 2018 More than 50 years have passed since the presentation of the Replicon Model which states that a positively acting initiator interacts with a specific site on a circular chromosome molecule to initiate DNA replication. Since then, the origin of chromosome
Flemming G. Hansen, Tove Atlung
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Unique and universal features of Epsilonproteobacterial origins of chromosome replication and DnaA-DnaA box interactions [PDF]
Frontiers in Microbiology, 2016 In bacteria, chromosome replication is initiated by the interaction of the initiator protein DnaA with a defined region of a chromosome at which DNA replication starts (oriC).
Pawel Jaworski +6 more
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Modulation of pPS10 host range by DnaA [PDF]
Molecular Microbiology, 2002 Narrow-host-range plasmid pPS10, originally found in Pseudomonas savastanoi, is unable to replicate in other strains such as Escherichia coli. Here, we report that the establishment of pPS10 in E.
Couturier, Martine +5 more
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The DnaA Cycle in Escherichia coli: Activation, Function and Inactivation of the Initiator Protein
Frontiers in Microbiology, 2017 This review summarizes the mechanisms of the initiator protein DnaA in replication initiation and its regulation in Escherichia coli. The chromosomal origin (oriC) DNA is unwound by the replication initiation complex to allow loading of DnaB helicases ...
Tsutomu Katayama +2 more
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Mutations of DnaA-boxes in the oriR region increase replication frequency of the MiniR1–1 plasmid
BMC Microbiology, 2018 Background The MiniR1–1 plasmid is a derivative of the R1 plasmid, a low copy cloning vector. Results Nucleotide sequencing analysis shows that the MiniR1–1 plasmid is a 6316 bp circular double-stranded DNA molecule with an oriR1 (origin for replication).
Yuan Yao +4 more
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Frontiers in Microbiology, 2018 The uvrB gene belongs to the SOS network, encoding a key component of the nucleotide excision repair. The uvrB promoter region contains three identified promoters with four LexA binding sites, one consensus and six potential DnaA binding sites.
Wurihan +9 more
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Cooperative DnaA Binding to the Negatively Supercoiled datA Locus Stimulates DnaA-ATP Hydrolysis
Cooperative DnaA Binding to the Negatively Supercoiled datA Locus Stimulates DnaA-ATP HydrolysisTimely initiation of replication in Escherichia coli requires functional regulation of the replication initiator, ATP-DnaA. The cellular level of ATP-DnaA increases just before initiation, after which its level decreases through hydrolysis of DnaA-bound ...
Sakai, Ryuji +11 more
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Putative Cooperative ATP-DnaA Binding to Double-Stranded DnaA Box and Single-Stranded DnaA-Trio Motif upon Helicobacter pylori Replication Initiation Complex Assembly [PDF]
, 2021 oriC is a region of the bacterial chromosome at which the initiator protein DnaA interacts with specific sequences, leading to DNA unwinding and the initiation of chromosome replication.
Weigel, C. +13 more
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Dominance of dnaA+ to dnaA in Escherichia coli [PDF]
Journal of Bacteriology, 1977 The dominance of dnaA+ to the dnaA508 mutation was complete and was unaffected by the presence of a copy of the chromosomal replication origin on the episome. These results prove that the dnaA gene of Escherichia coli produces a diffusible product.
F, Gotfried, J A, Wechsler
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Evolutionary Changes in DnaA-Dependent Chromosomal Replication in Cyanobacteria
Frontiers in Microbiology, 2020 Replication of the circular bacterial chromosome is initiated at a unique origin (oriC) in a DnaA-dependent manner in which replication proceeds bidirectionally from oriC to ter. The nucleotide compositions of most bacteria differ between the leading and
Ryudo Ohbayashi +11 more
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