Results 41 to 50 of about 9,669 (211)
The bacterial replication origin BUS promotes nucleobase capture
Nature Communications, 2023 Genome duplication is essential for the proliferation of cellular life and this process is generally initiated by dedicated replication proteins at chromosome origins.
Simone Pelliciari +14 more
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, 2019 DnaA is the widely conserved bacterial AAA+ ATPase that functions as both the replication initiator and a transcription factor. In many organisms, DnaA controls expression of its own gene and likely several others during growth and in response to ...
Grossman, Alan Davis +2 more
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Research on DnaA in the early days
Research in Microbiology, 2020 The Escherichia coli chromosome is a circular double helix. DNA polymerase, therefore, cannot use it directly as a template for polymerization until it has first been unwound. The DnaA protein opens the chromosome at a unique and specific site (oriC), which allows the polymerase to begin DNA replication.
openaire +3 more sources
Frontiers in Microbiology, 2021 Genome duplication is a critical event in the reproduction cycle of every cell. Because all daughter cells must inherit a complete genome, chromosome replication is tightly regulated, with multiple mechanisms focused on controlling when chromosome ...
Julia E. Grimwade, Alan C. Leonard
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, 2017 A) Coomassie-stained SDS PAGE showing the purification of DnaA by gel filtration chromatography following nickel NTA affinity chromatography; shown are peak elution fractions.
Katrin Schenk (3720469) +8 more
core +1 more source
DnaA-dependent riboswitch for transcription attenuation
, 2020 Transcription attenuation has been believed to be controlled by alternative configurations of RNA secondary structures through arresting or releasing the ribosome on the leader RNA molecule in response to limitation or sufficiency of specific amino acid.
Morigen, Morigen
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Occlusion of RNA Polymerase by Oligomerization of DnaA Protein over the dnaA Promoter of Escherichia coli [PDF]
Journal of Biological Chemistry, 1997 DnaA protein, the initiator protein for initiation of Escherichia coli chromosomal replication, has been shown to repress its own expression from two dnaA promoters, 1P and 2P. The sequence-specific binding of DnaA protein to the DnaA box, located between the two promoters, results in subsequent oligomerization of DnaA protein.
Y S, Lee, D S, Hwang
openaire +2 more sources
Frontiers in Microbiology, 2016 The initiation of bacterial chromosomal replication is regulated by multiple pathways. To explore novel regulators, we isolated multicopy suppressors for the cold-sensitive hda-185 ΔsfiA(sulA) mutant.
Yaunori eNoguchi, Tsutomu eKatayama
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PLoS Pathogens, 2020 Genomic dissection of antibiotic resistance in bacterial pathogens has largely focused on genetic changes conferring growth above a single critical concentration of drug.
Nathan D Hicks +10 more
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Frontiers in Microbiology, 2015 Based on the complete genome of Cyanothece ATCC 51142, the oriCs of both the circular and linear chromosomes in Cyanothece ATCC 51142 have been predicted by utilizing a web-based system Ori-Finder.
He eHuang +5 more
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