Results 41 to 50 of about 8,858 (210)
Transcription termination in the Escherichia coli dnaA gene is not mediated by the internal DnaA box
Journal of Bacteriology, 1995 DnaA protein is a DNA-binding protein which recognizes a 9-bp consensus sequence called the DnaA box. By binding to DnaA boxes, DnaA protein regulates initiation of chromosomal replication and transcription of several genes. The dnaA gene contains two DnaA boxes, one located in the regulatory region and one within the structural gene. In this paper, we
I, Pérez-Roger +2 more
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DnaA initiator—also a transcription factor [PDF]
Molecular Microbiology, 1997 The replication‐initiator protein DnaA is ubiquitous in the eubacterial world. It binds to an asymmetric 9 bp consensus DNA sequence, the DnaA box. Besides its primary function as an initiator, it acts as a transcription factor that represses or activates several genes, or terminates transcription, depending on the location and arrangement of DnaA ...
W, Messer, C, Weigel
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, 2017 A) Coomassie-stained SDS PAGE showing the purification of DnaA by gel filtration chromatography following nickel NTA affinity chromatography; shown are peak elution fractions.
Katrin Schenk (3720469) +8 more
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Research on DnaA in the early days
Research in Microbiology, 2020 The Escherichia coli chromosome is a circular double helix. DNA polymerase, therefore, cannot use it directly as a template for polymerization until it has first been unwound. The DnaA protein opens the chromosome at a unique and specific site (oriC), which allows the polymerase to begin DNA replication.
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Frontiers in Microbiology, 2016 The initiation of bacterial chromosomal replication is regulated by multiple pathways. To explore novel regulators, we isolated multicopy suppressors for the cold-sensitive hda-185 ΔsfiA(sulA) mutant.
Yaunori eNoguchi, Tsutomu eKatayama
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PLoS Pathogens, 2020 Genomic dissection of antibiotic resistance in bacterial pathogens has largely focused on genetic changes conferring growth above a single critical concentration of drug.
Nathan D Hicks +10 more
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Identification and characterization of a cis-encoded antisense RNA associated with the replication process of Salmonella enterica serovar Typhi. [PDF]
PLoS ONE, 2013 Antisense RNAs that originate from the complementary strand of protein coding genes are involved in the regulation of gene expression in all domains of life.
Isaac Dadzie +7 more
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Frontiers in Microbiology, 2015 Based on the complete genome of Cyanothece ATCC 51142, the oriCs of both the circular and linear chromosomes in Cyanothece ATCC 51142 have been predicted by utilizing a web-based system Ori-Finder.
He eHuang +5 more
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Multiplex Modular Nanorobotic Systems with Catalytic Activity under Magnetic Navigation
Advanced Functional Materials, Volume 36, Issue 48, 15 June 2026.We present modular nanorobots composed of a magnetic propulsion module and different extension modules carrying functional activities, assembled via DNA base pairing. The system integrates propulsion, optical tracking, enzymatic catalysis, and cell docking in a programmable manner.
Voichita Mihali +7 more
wiley +1 more source
Acetylation of Lysine 243 Inhibits the oriC Binding Ability of DnaA in Escherichia coli
Frontiers in Microbiology, 2017 DNA replication initiation is a central event in the cell cycle, and it is strictly controlled by multiple regulatory mechanisms. Our previous work showed that acetylation of residue lysine (K) 178 prevents DnaA from binding to ATP, which leads to the ...
Yu-Feng Yao +4 more
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