Results 51 to 60 of about 9,669 (211)

The trimeric Shu complex in C. elegans is an ATPase that remodels RAD51 filaments in the homologous recombination‐associated DNA damage response

The FEBS Journal, EarlyView.
The C. elegans Shu complex (RFS‐1/RIP‐1/SWS‐1) is a DNA‐dependent ATPase that regulates RAD‐51 filaments during homologous recombination. The trimer preferentially binds 5′‐exposed DNA, remodels RAD‐51 filaments via ATP hydrolysis, and stabilizes filaments through ATP binding.
Sam Siu Hang Chu, Guangxin Xing, Kichang Paik, Anton Gartner, Hong Ling   +4 more
wiley   +1 more source

DnaA initiator—also a transcription factor [PDF]

Molecular Microbiology, 1997
The replication‐initiator protein DnaA is ubiquitous in the eubacterial world. It binds to an asymmetric 9 bp consensus DNA sequence, the DnaA box. Besides its primary function as an initiator, it acts as a transcription factor that represses or activates several genes, or terminates transcription, depending on the location and arrangement of DnaA ...
W, Messer, C, Weigel
openaire   +2 more sources

Acetylation of Lysine 243 Inhibits the oriC Binding Ability of DnaA in Escherichia coli

Frontiers in Microbiology, 2017
DNA replication initiation is a central event in the cell cycle, and it is strictly controlled by multiple regulatory mechanisms. Our previous work showed that acetylation of residue lysine (K) 178 prevents DnaA from binding to ATP, which leads to the ...
Yu-Feng Yao, Yu-Feng Yao, Shuxian Li, Qiufen Zhang, Zhihong Xu   +4 more
doaj   +1 more source

Identification and characterization of a cis-encoded antisense RNA associated with the replication process of Salmonella enterica serovar Typhi. [PDF]

PLoS ONE, 2013
Antisense RNAs that originate from the complementary strand of protein coding genes are involved in the regulation of gene expression in all domains of life.
Isaac Dadzie, Shungao Xu, Bin Ni, Xiaolei Zhang, Haifang Zhang, Xiumei Sheng, Huaxi Xu, Xinxiang Huang   +7 more
doaj   +1 more source

Pathological replication in cells lacking RecG DNA translocase [PDF]

, 2009
This is an open access article, shared under a Creative Commons licence. Copyright © 2009 The Authors.Little is known about what happens when forks meet to complete DNA replication in any organism.
Lloyd, RG, Robert G. Lloyd, Lynda Harris, Harris, L, Christian J. Rudolph, Amy L. Upton, Rudolph, CJ, Upton, AL   +7 more
core   +1 more source

Gender Inequality and Socio‐Economic Disadvantages Associated With Obesity in Women Compared to Men: A Rapid Review and Meta‐Analysis of Observational Studies From High‐Income Countries

Obesity Reviews, EarlyView.
ABSTRACT Objective To assess whether obesity‐related socio‐economic disadvantages in wages, employment, and workplace discrimination equally affect women compared to men in high‐income countries. Method We searched databases and Google Scholar from inception to March 2025. Data on wages, employment, and perceived discrimination were pooled using random‐
Nana Ama Asi Danso, Paul P. Fahey, Navindhra Naidoo, Rebecca Wu, Evan Atlantis   +4 more
wiley   +1 more source

Relative DNA binding by ATP-DnaA-his compared to ADP-DnaA-his.

, 2015
(A) The ratio of the amount of DNA recovered bound to ATP-DnaA-his vs. ADP-DnaA-his is plotted versus the DnaA concentration. Background binding was subtracted prior to calculating the ratio.
Alan D. Grossman (237649), Janet L. Smith (213446)   +1 more
core   +1 more source

Impact of the GouM transporter on secondary metabolism activation and production yield in Streptomyces noursei strain CK‐15

New Plant Protection, Volume 3, Issue 3, September 2026.
Overexpression of the gouM transporter gene in Streptomyces noursei CK‐15 enhances gougerotin production by 114% and activates silent biosynthetic gene clusters. This finding links transporter activity to metabolite efflux and secondary metabolism, offering a strategy for natural product discovery and strain optimization.
Qianying Zhou, Hua Yu, Rouhallah Sharifi, Muhammad Usman, Shun Lai Ei, Abdel‐Hamied M. Rasmey, Beibei Ge   +6 more
wiley   +1 more source

A Structural Basis for the Regulatory Inactivation of DnaA [PDF]

Journal of Molecular Biology, 2009
Regulatory inactivation of DnaA is dependent on Hda (homologous to DnaA), a protein homologous to the AAA+ (ATPases associated with diverse cellular activities) ATPase region of the replication initiator DnaA. When bound to the sliding clamp loaded onto duplex DNA, Hda can stimulate the transformation of active DnaA-ATP into inactive DnaA-ADP.
Qingping, Xu, Daniel, McMullan, Polat, Abdubek, Tamara, Astakhova, Dennis, Carlton, Connie, Chen, Hsiu-Ju, Chiu, Thomas, Clayton, Debanu, Das, Marc C, Deller, Lian, Duan, Marc-Andre, Elsliger, Julie, Feuerhelm, Joanna, Hale, Gye Won, Han, Lukasz, Jaroszewski, Kevin K, Jin, Hope A, Johnson, Heath E, Klock, Mark W, Knuth, Piotr, Kozbial, S, Sri Krishna, Abhinav, Kumar, David, Marciano, Mitchell D, Miller, Andrew T, Morse, Edward, Nigoghossian, Amanda, Nopakun, Linda, Okach, Silvya, Oommachen, Jessica, Paulsen, Christina, Puckett, Ron, Reyes, Christopher L, Rife, Natasha, Sefcovic, Christine, Trame, Henry, van den Bedem, Dana, Weekes, Keith O, Hodgson, John, Wooley, Ashley M, Deacon, Adam, Godzik, Scott A, Lesley, Ian A, Wilson   +43 more
openaire   +2 more sources

Re-wiring of energy metabolism promotes viability during hyperreplication stress in E. coli. [PDF]

PLoS Genetics, 2017
Chromosome replication in Escherichia coli is initiated by DnaA. DnaA binds ATP which is essential for formation of a DnaA-oriC nucleoprotein complex that promotes strand opening, helicase loading and replisome assembly.
Godefroid Charbon, Christopher Campion, Siu Hung Joshua Chan, Louise Bjørn, Allan Weimann, Luís Cláudio Nascimento da Silva, Peter Ruhdal Jensen, Anders Løbner-Olesen   +7 more
doaj   +1 more source