Results 91 to 100 of about 15,397 (180)

The WHO Classification of Genetic Tumour Syndromes: Considerations for histopathology

Histopathology, Volume 88, Issue 7, Page 1291-1294, June 2026.
Ian A Cree, Mark J Arends, Joseph D Khoury, Erika RE Denton, Anthony J Gill, Alexander J Lazar, Ian M Frayling, Stefan M Pfister, Mark A Rubin, Katia RM Leite, Raymond Dalgleish, Elspeth A Bruford, Sharon Plon, Ada Hamosh, Michael Francis Walsh, Gabrielle Goldman‐Lévy, Harshima Wijesinghe, William D Foulkes, Dilani Lokuhetty   +18 more
wiley   +1 more source

Interdependence of Pasha and Drosha for localization and function of the Microprocessor in C. elegans

Nature Communications
Primary microRNA (pri-miRNA) transcripts are processed by the Microprocessor, containing the ribonuclease Drosha and its RNA-binding partner DGCR8/Pasha. In a forward genetic screen utilizing a fluorescence-based sensor that monitors pri-miRNA processing
Thiago L. Knittel, Brooke E. Montgomery, Kailee J. Reed, Madeleine C. Chong, Ida J. Isolehto, Erin R. Cafferty, Margaret J. Smith, Reese A. Sprister, Colin N. Magelky, Hataichanok Scherman, René F. Ketting, Taiowa A. Montgomery   +11 more
doaj   +1 more source

Non-canonical RNA substrates of Drosha lack many of the conserved features found in primary microRNA stem-loops

Scientific Reports
The RNase III enzyme Drosha has a central role in microRNA (miRNA) biogenesis, where it is required to release the stem-loop intermediate from primary (pri)-miRNA transcripts. However, it can also cleave stem-loops embedded within messenger (m)RNAs. This
Karen Gu, Lawrence Mok, Matthew J. Wakefield, Mark M. W. Chong   +3 more
doaj   +1 more source

Study of the association between Dicer (rs3742330 A>G) and Drosha (rs10719 C>T) gene polymorphisms and the risk of recurrent pregnancy loss

Fiyz̤, 2018
Background: Drosha and Dicer are important molecules that play critical regulatory roles in the biogenesis of micro-RNA. Genetic polymorphism in the Drosha and Dicer can cause defect on the embryo implantation and lead to the recurrent abortion.
Negin Mohseni , Saeid Ghorbian
doaj  

Analysis of MicroRNA Processing Machinery Gene DROSHA, DICER1, and XPO5 Variants Association with Atherosclerosis: A Case–control Study

Biomedical and Biotechnology Research Journal
Background: Atherosclerosis, a primary cause of coronary artery disease, involves chronic inflammatory arterial changes and contributes significantly to global vascular mortality.
Manar F. Atoum, Dalya Alowaisy, Ammar Ali Deeb   +2 more
doaj   +1 more source

Drosha in mesangial cells regulates Glomerular Capillary Tufts Formation Through Drosha/Ribosome/Gata3 Axis

Abstract Drosha is a critical regulator of kidney development; its loss or mutation, identified in a subsets of Wilms tumor (WT), a pediatric kidney cancer, leads to nephric cap mesenchyme developmental defects. Here, we investigated the role of Drosha in mesangial cells and its impact on glomerular capillary tuft formation.
Jin Tang, Lang Qin, Jiajia Qin, Zixuan Fan, Tingxuan Xu, Wenjun Xiao, Yonghui He, Xin Li, Zhenbo Yuan, Weiqian Chen, Chuwen Lin, Xuan Jiang   +11 more
openaire   +1 more source

DROSHA Gene [PDF]

, 2020
openaire   +1 more source

Separable roles for Microprocessor and its cofactors, ERH and SAFB1/2, during microRNA cluster assistance. [PDF]

Genes Dev
Shang R, Popitsch N, Lee S, Ameres SL, Lai EC.   +4 more
europepmc   +2 more sources

DROSHA Gene Mutation [PDF]

, 2020
openaire   +1 more source

Drosha [PDF]

, 2019
openaire   +1 more source