Results 1 to 10 of about 31,514 (218)
microRNA biogenesis and stabilization in plants [PDF]
Fundamental Research, 2023 MicroRNAs (miRNAs) are short endogenous non-coding RNAs that regulate gene expression at the post-transcriptional level in a broad range of eukaryotic species.
Ye Xu, Xuemei Chen
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MicroRNA biogenesis and variability [PDF]
Biomolecular Concepts, 2013 MicroRNAs (miRNAs) are cell-endogenous small noncoding RNAs that, through RNA interference, are involved in the posttranscriptional regulation of mRNAs.
García-López Jesús +2 more
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Versatility of MicroRNA biogenesis. [PDF]
PLoS ONE, 2011 MicroRNAs (miRNAs) are short single-stranded RNA molecules that regulate gene expression. MiRNAs originate from large primary (pri) and precursor (pre) transcripts that undergo various processing steps along their biogenesis pathway till they reach their
Naama Volk, Noam Shomron
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The Role of Exportin-5 in MicroRNA Biogenesis and Cancer [PDF]
Genomics, Proteomics and Bioinformatics, 2018 MicroRNAs (miRNAs) are conserved small non-coding RNAs that play an important role in the regulation of gene expression and participate in a variety of biological processes.
Ke Wu, Juan He, Wenchen Pu
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Network Regulation of microRNA Biogenesis and Target Interaction [PDF]
Cells, 2023 MicroRNAs (miRNAs) are versatile, post-transcriptional regulators of gene expression. Canonical miRNAs are generated through the two-step DROSHA- and DICER-mediated processing of primary miRNA (pri-miRNA) transcripts with optimal or suboptimal features ...
Shintaro Komatsu +2 more
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A plant bunyaviral protein disrupts SERRATE phase separation to modulate microRNA biogenesis during viral pathogenesis [PDF]
Nature CommunicationsLiquid-liquid phase separation (LLPS) regulates diverse biological functions by mediating the assembly of biomolecular condensates. However, it remains unclear how host LLPS is targeted by viruses during infection.
Jing Zou +17 more
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Regulatory circuit of human microRNA biogenesis. [PDF]
PLoS Computational Biology, 2007 miRNAs (microRNAs) are a class of endogenous small RNAs that are thought to negatively regulate protein production. Aberrant expression of many miRNAs is linked to cancer and other diseases.
Ji Lee +3 more
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MicroRNA biogenesis pathways in cancer [PDF]
Nature Reviews Cancer, 2015 MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and overexpression of individual 'oncomiRs' or genetic loss of tumour suppressor miRNAs are associated with human cancer and are sufficient to drive tumorigenesis in mouse models. Furthermore, global miRNA depletion caused by genetic and epigenetic alterations in components of
Shuibin Lin, Richard I Gregory
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Regulatory role of RNA-binding proteins in microRNA biogenesis [PDF]
Frontiers in Molecular BiosciencesMicroRNAs (miRNAs) are small non-coding RNAs that silence gene expression through their interaction with complementary sequences in the 3′ untranslated regions (UTR) of target mRNAs. miRNAs undergo a series of steps during their processing and maturation,
Claire Hynes, Pavan Kumar Kakumani
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MicroRNA Biogenesis, Gene Regulation Mechanisms, and Availability in Foods [PDF]
Non-Coding RNAMicroRNAs (miRNAs) are small, non-coding RNAs that control gene expression by degrading or repressing mRNA translation into proteins. Research recently suggested that food-derived miRNAs are bioavailable and may be absorbed in the gastrointestinal tract (
Amilton S. de Mello +3 more
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