Results 11 to 20 of about 31,660 (233)
Versatility of MicroRNA biogenesis. [PDF]
PLoS ONE, 2011 MicroRNAs (miRNAs) are short single-stranded RNA molecules that regulate gene expression. MiRNAs originate from large primary (pri) and precursor (pre) transcripts that undergo various processing steps along their biogenesis pathway till they reach their
Naama Volk, Noam Shomron
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Regulatory circuit of human microRNA biogenesis. [PDF]
PLoS Computational Biology, 2007 miRNAs (microRNAs) are a class of endogenous small RNAs that are thought to negatively regulate protein production. Aberrant expression of many miRNAs is linked to cancer and other diseases.
Ji Lee +3 more
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MicroRNA biogenesis pathway alterations in aging [PDF]
Extracell Vesicles Circ Nucl Acids, 2023 Jorge Sanz-Ros, Consuelo Borràs
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The Role of Exportin-5 in MicroRNA Biogenesis and Cancer [PDF]
Genomics, Proteomics & Bioinformatics, 2018 MicroRNAs (miRNAs) are conserved small non-coding RNAs that play an important role in the regulation of gene expression and participate in a variety of biological processes.
Ke Wu, Juan He, Wenchen Pu, Yong Peng
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Multifaceted Regulation of MicroRNA Biogenesis: Essential Roles and Functional Integration in Neuronal and Glial Development [PDF]
International Journal of Molecular Sciences, 2021 Yue Feng
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Antioxidants, 2023 Ischemic cardiomyopathy (ICM) is associated with abnormal microRNA expression levels that involve an altered gene expression profile. However, little is known about the underlying causes of microRNA disruption in ICM and whether microRNA maturation is ...
Lorena Pérez-Carrillo +10 more
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Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation [PDF]
Frontiers in Endocrinology, 2018 Chun Peng +2 more
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MicroRNA Biogenesis and Cancer [PDF]
Cancer Research, 2005 Abstract MicroRNAs (miRNA) are a recently discovered family of short non–protein-coding RNAs that negatively regulate gene expression. Recent studies of miRNAs highlight a requirement for cell viability. Posttranscriptional silencing of target genes by miRNAs occurs either by targeting specific cleavage of homologous mRNAs, or by ...
Richard I, Gregory, Ramin, Shiekhattar
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MicroRNA clustering on the biogenesis of suboptimal microRNAs [PDF]
Applied Biological Chemistry, 2021 AbstractMost microRNAs (miRNAs) are processed by two ribonuclease III enzymes. The first cleavage is performed by Microprocessor that is composed of RNase III enzyme Drosha and DGCR8, and the second by another RNase III enzyme Dicer. There are many examples of miRNAs that are poor substrates for Drosha and Dicer, owing to their suboptimal structures ...
Sehee Park, Igojo Kang, Chanseok Shin
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MicroRNA Biogenesis Pathway Genes Are Deregulated in Colorectal Cancer [PDF]
International Journal of Molecular Sciences, 2019 Tana Macháčková +2 more
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