Results 101 to 110 of about 17,302 (170)

Study of the association between Dicer (rs3742330 A>G) and Drosha (rs10719 C>T) gene polymorphisms and the risk of recurrent pregnancy loss

Fiyz̤, 2018
Background: Drosha and Dicer are important molecules that play critical regulatory roles in the biogenesis of micro-RNA. Genetic polymorphism in the Drosha and Dicer can cause defect on the embryo implantation and lead to the recurrent abortion.
Negin Mohseni , Saeid Ghorbian
doaj  

Analysis of MicroRNA Processing Machinery Gene DROSHA, DICER1, and XPO5 Variants Association with Atherosclerosis: A Case–control Study

Biomedical and Biotechnology Research Journal
Background: Atherosclerosis, a primary cause of coronary artery disease, involves chronic inflammatory arterial changes and contributes significantly to global vascular mortality.
Manar F. Atoum, Dalya Alowaisy, Ammar Ali Deeb   +2 more
doaj   +1 more source

Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs

, 2012
Temporal regulation of embryonic neurogenesis is controlled by hypostable transcription factors. The mechanism of the process is unclear. Here we show that the RNase III Drosha and DGCR8 (also known as Pasha), key components of the microRNA (miRNA ...
Dan R Littman, Mark M W Chong, Knuckles, P., Littman, D. R., Stuart A Wilson, Vogt, M. A., Miriam A Vogt, Milo, M., Taylor, V., Guillaume M Hautbergue, Chong, M. M., Philip Knuckles, Wilson, S. A., Lugert, S., Hautbergue, G. M., Sebastian Lugert, Verdon Taylor, Marta Milo   +17 more
core   +1 more source

The effects of DROSHA rs10719T>C variant on colorectal cancer (CRC) development modulated by diabetes mellitus (DM).

, 2015
Y-axis represents fold changes between DROSHA genotype TT+TC and DROSHA genotype CC. Each row represents the patients with or without DM. Each column represents DROSHA genotype TT+TC and DROSHA genotype CC.
Jung Jae Ko (765713), Jisu Oh (275935), Jung Ki Yoo (765715), Jong Woo Kim (765717), Young Joo Jeon (128378), Nam Keun Kim (128410), Sung Hwan Cho (765712), Doyeun Oh (765716), Jung Oh Kim (765714)   +8 more
core   +1 more source

Expanding the role of Drosha to the regulation of viral gene expression

, 2011
It is well-appreciated that viruses use host effectors for macromolecular synthesis and as regulators of viral gene expression. Viruses can encode their own regulators, but often use host-encoded factors to optimize replication. Here, we show that Drosha,
Christopher S. Sullivan, Yao-Tang Lin
core   +1 more source

Germline Pathogenic DROSHA Variants Are Linked to Pineoblastoma and Wilms Tumor Predisposition

Purpose: DROSHA, DGCR8, and DICER1 regulate miRNA biogenesis and are commonly mutated in cancer. Although DGCR8 and DICER1 germline pathogenic variants (GPV) cause autosomal dominant tumor predisposition, no association between DROSHA GPVs and clinical ...
Plon, Sharon E, Perrino, Melissa R, Huang, Kuan-Lin, Saulnier Sholler, Giselle, Fiorica, Peter N, McGee, Rose B, Schiffman, Joshua D, Bao, Riyue, Ingster, Olivier, Haley, Jeremy S, Al-Kateb, Hussam, Masliah-Planchon, Julien, Schultz, Kris Ann P, Onel, Kenan, Sasaki, Mark M, Ng, Anita, Wong, Jennifer, Roy, Angshumoy, Kaufman, Rebecca S, Pribnow, Allison, Fowler, Trent, Chen, Kenneth S, Jackson, Sarah A, Carey, David J, Filser, Mathilde, Kim, Jung, Lin, Frank Y, Corbett, Ryan J, Michalak-Provost, Sophie, Golmard, Lisa, Stewart, Douglas R, Rokita, Jo Lynne, Williams Parsons, D, Diskin, Sharon J, Stoppa-Lyonnet, Dominique, Bourdeaut, Franck, Brahimi, Afane   +36 more
core   +1 more source

Molecular mechanisms regulating differential expression of individual miRNAs within polycistronic clusters. [PDF]

Front Mol Biosci
Maltseva D, Tonevitsky A.
europepmc   +1 more source

Separable roles for Microprocessor and its cofactors, ERH and SAFB1/2, during microRNA cluster assistance. [PDF]

Genes Dev
Shang R, Popitsch N, Lee S, Ameres SL, Lai EC.   +4 more
europepmc   +2 more sources

The Hidden Layer of MicroRNA Regulation in Gynecologic Cancers: IsomiRs, Arm Switching, and RNA Epitranscriptomic Modifications. [PDF]

Int J Mol Sci
Pérez-Navarro Y, López-Camarillo C, Flores-García LC, Alvarez-Sánchez ME, Campoy Ramírez A, Salinas-Vera YM.   +5 more
europepmc   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops. [PDF]

Adv Sci (Weinh)
Zhang X, Wu Y, Hou J, Gao L, Pan L, Shen C, Zhao C, Gao F, Zhang Y, Ren L, Fang X, Dun X, Liu S, Liu L.   +13 more
europepmc   +1 more source