Arthropod exosomal glycine-rich protein as a potential vaccine candidate effectively reduces tick blood-feeding and pathogen transmission. [PDF]
Ahmed W +6 more
europepmc +1 more source
ABSTRACT Quantitative PCR (qPCR) employing either non‐specific dyes or gene‐specific dye‐labelled probes is a commonly used technique for the quantification of viral nucleic acids. While commercial kits often come equipped with their own proprietary standards, many research endeavours necessitate the preparation of bespoke standards that suit the ...
Cüneyt Tamer +5 more
wiley +1 more source
Directed Evolution of T7 RNA Polymerase Minimizes dsRNA By-product and Enables High-Fidelity mRNA Synthesis for Demanding Therapeutic Applications. [PDF]
Qin W +6 more
europepmc +1 more source
The distemper‐infected dogs presented with an upregulated expression of the immune recognition receptors TLR3, TLR4 and TLR9. In the distemper‐infected dogs, there was a positive correlation between the TLR1 and PWD, TLR4 and WBC, Gran and Gran%, TLR5 and HCT, TLR6 and Gran%, TLR7 and MCV and TLR7 and PDW, as well as a negative correlation between the ...
İlknur Karaca Bekdik +4 more
wiley +1 more source
Contact Unmodified Antisense DNA Biotechnology (CUADb)-Based Oligonucleotide Insecticides and RNA Biocontrols: Molecular Bases and Potential in Plant Protection. [PDF]
Oberemok V +4 more
europepmc +1 more source
U‐indel RNA editing targets mRNA:gRNA duplexes through three key complexes that collectively govern assembly, specificity, catalysis, and developmental regulation. Modern tools, including artificial intelligence, analyze the organization, dynamics, and evolution of the remarkable holo‐editosome, opening new avenues in RNA biology and therapy.
Suzanne M. McDermott +18 more
wiley +1 more source
Life stage-dependent RNA interference in the tropical rock lobster <i>Panulirus ornatus</i>: mechanistic insights from RNA-seq and functional studies. [PDF]
Banks TM +5 more
europepmc +1 more source
Select Small Non‐Coding RNAs Are Determinants of Survival in Older Adults
Circulating small RNAs were profiled by RNA sequencing in a well‐characterized cohort and evaluated alongside 187 clinical variables to predict survival. Models incorporating circulating small RNAs, including parsimonious subsets, outperformed age and clinical factors alone (AUC), with causal analyses supported by experimental evidence from the ...
Virginia Byers Kraus +12 more
wiley +1 more source
RNA-triggered innate immunity: friend and foe. [PDF]
Henschel M, Conte MR, Martinez-Nunez RT.
europepmc +1 more source
doublesex regulates sexual dimorphism in elytral color patterns of Harmonia axyridis by downregulating the color patterning gene h in males. This regulatory link diverged in derived color morphs, coinciding with the loss of sex‐specific elytral color patterns.
Soichi Yeki +7 more
wiley +1 more source

