Results 31 to 40 of about 74,293 (296)

RNAi-Mediated Management of Whitefly Bemisia tabaci by Oral Delivery of Double-stranded RNAs

Proceedings, 2019
The whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae) is a significant global pest of economically important vegetable, fibre, and ornamental crops. Whiteflies directly damage the plants by piercing and sucking essential nutrients, indirectly through ...
Ritesh G Jain, Karl Robinson, Neena Mitter   +2 more
doaj   +1 more source

CaP Nanoparticles Improve the Effect of dsRNA on Gene Expression, Growth, and Mycotoxin Production of Toxigenic <i>Fusarium graminearum</i>. [PDF]

Int J Mol Sci
Stakheev AA, Bagdasarova P, Rogozhin EA, Tikhomirova V, Popova E, Akhmetova A, Kost O, Kalinina NO, Taliansky M, Zavriev SK.   +9 more
europepmc   +3 more sources

Flipped Over U: Structural Basis for dsRNA Cleavage by the SARS-CoV-2 Endoribonuclease

bioRxiv, 2022
Coronaviruses generate double-stranded (ds) RNA intermediates during viral replication that can activate host immune sensors. To evade activation of the host pattern recognition receptor MDA5, coronaviruses employ Nsp15, which is uridine-specific ...
M. Frazier, I. Wilson, J. Krahn, K. J. Butay, L. Dillard, M. Borgnia, R. Stanley   +6 more
semanticscholar   +1 more source

Carbon Dots Boost dsRNA Delivery in Plants and Increase Local and Systemic siRNA Production

bioRxiv, 2022
Carbon dots (CDs) have been proposed for nucleic acid delivery in many biological applications. In this work we have obtained carbon dots by a hydrothermal synthesis method for developing nanocomposites with dsRNA.
Josemaría Delgado-Martín, Alejo Delgado-Olidén, L. Velasco   +2 more
semanticscholar   +1 more source

Structural basis for Dicer-like function of an engineered RNase III variant and insights into the reaction trajectory of two-Mg2+-ion catalysis

RNA Biology, 2022
The RNase III family of dsRNA-specific endonucleases is exemplified by prokaryotic RNase III and eukaryotic Rnt1p, Drosha, and Dicer. Structures of Aquifex aeolicus RNase III (AaRNase III) and Saccharomyces cerevisiae Rnt1p (ScRnt1p) show that both ...
Sudhaker Dharavath, Gary X. Shaw, Xinhua Ji   +2 more
doaj   +1 more source

Studying the effect of double-stranded RNA upon activity of mouse splenocytes using flow cytometry

Медицинская иммунология, 2023
Ribonucleic acids (RNA), in particular, double-stranded RNAs, due to their ability to modulate innate immune responses, are of undoubted interest in view of their usage as vaccine adjuvants.
E. S. Tsyplenkova, E. A. Vyazovaya, E. D. Danilenko   +2 more
doaj   +1 more source

Selection for high levels of resistance to double-stranded RNA (dsRNA) in Colorado potato beetle (Leptinotarsa decemlineata Say) using non-transgenic foliar delivery

Scientific Reports, 2021
Insecticidal double-stranded RNAs (dsRNAs) silence expression of vital genes by activating the RNA interference (RNAi) mechanism in insect cells. Despite high commercial interest in insecticidal dsRNA, information on resistance to dsRNA is scarce ...
S. Mishra, James Dee, W. Moar, J. Dufner-Beattie, James Baum, N. Dias, A. Alyokhin, A. Buzza, S. Rondon, M. Clough, S. Menasha, R. Groves, Justin Clements, K. Ostlie, G. Felton, T. Waters, W. E. Snyder, J. Jurat-Fuentes   +17 more
semanticscholar   +1 more source

dsRNA Uptake in Adult Drosophila [PDF]

, 2011
RNA interference (RNAi) is a conserved sequence-specific gene silencing mechanism that is induced by double-stranded RNA (dsRNA). The development of methods that allow internalization of dsRNA and concomitant silencing of the desired gene has not stopped since the first demonstration of RNAi in Caenorhabditis elegans.
Obadia, Benjamin, Saleh, Maria-Carla
openaire   +2 more sources

Stimulating effect of double-stranded yeast RNA on the activity of interferon system genes

Медицинская иммунология, 2021
Influence of double-stranded RNA (dsRNA) from Saccharomyces cerevisiae yeast upon expression levels of the macrophage genes encoding TLR3 receptor, interferons alpha and beta (IFNα, IFNβ), 2’,5’-oligoadenylate synthetase (OAS) and protein kinase R (PKR ...
A. V. Bateneva, S. G. Gamaley, E. D. Danilenko, R. L. Lebedev   +3 more
doaj   +1 more source

Spliceosome-Targeted Therapies Induce dsRNA Responses [PDF]

Immunity, 2021
In a recent issue of Cell, Bowling et al. describe a mechanism by which spliceosome-targeted therapies result in intron-containing transcripts that form double-stranded RNAs (dsRNAs), thereby activating tumor antiviral signaling (viral mimicry) and downstream adaptive immunity.
Charles A, Ishak, Helen, Loo Yau, Daniel D, De Carvalho   +2 more
openaire   +2 more sources