A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]
, 2017 Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel +1 more
core +6 more sources
A dsRNA virus with filamentous viral particles [PDF]
Nature Communications, 2017 AbstractViruses with double-stranded RNA genomes form isometric particles or are capsidless. Here we report a double-stranded RNA virus, Colletotrichum camelliae filamentous virus 1 (CcFV-1) isolated from a fungal pathogen, that forms filamentous particles. CcFV-1 has eight genomic double-stranded RNAs, ranging from 990 to 2444 bp, encoding 10 putative
Hengxia Jia +6 more
openaire +4 more sources
Plant Protection Science, 2002 Citrus tristeza Closterovirus (CTV) is widespread in major citrus-growing regions of the world often causing destructive diseases. Citrus samples were taken from orchards in the Croatian coastal region.
S. Černi, D. Škorić, M. Krajačić
doaj +1 more source
Systematic identification of abundant A-to-I editing sites in the human transcriptome [PDF]
Nature Biotechnology 22, 1001-1005 (2004), 2004 RNA editing by members of the double-stranded RNA-specific ADAR family leads to site-specific conversion of adenosine to inosine (A-to-I) in precursor messenger RNAs. Editing by ADARs is believed to occur in all metazoa, and is essential for mammalian development.
arxiv +1 more source
Biosafety of GM Crop Plants Expressing dsRNA: Data Requirements and EU Regulatory Considerations
Frontiers in Plant Science, 2020 The use of RNA interference (RNAi) enables the silencing of target genes in plants or plant-dwelling organisms, through the production of double stranded RNA (dsRNA) resulting in altered plant characteristics. Expression of properly synthesized dsRNAs in
S. Arpaia +10 more
semanticscholar +1 more source
RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design [PDF]
, 2011 A
Albrechtsen, Merete +72 more
core +3 more sources
ICTV Virus Taxonomy Profile: Chrysoviridae [PDF]
, 2019 Members of the family Chrysoviridae are isometric, non-enveloped viruses with segmented, linear, dsRNA genomes. There are 3–7 genomic segments, each of which is individually encapsidated.
Castón, José R. +8 more
core +1 more source
Time-delayed model of RNA interference [PDF]
Ecol. Compl. 30, 11-25 (2017), 2016 RNA interference (RNAi) is a fundamental cellular process that inhibits gene expression through cleavage and destruction of target mRNA. It is responsible for a number of important intracellular functions, from being the first line of immune defence against pathogens to regulating development and morphogenesis.
arxiv +1 more source
Assessing the Risks of Topically Applied dsRNA-Based Products to Non-target Arthropods
Frontiers in Plant Science, 2020 RNA interference (RNAi) is a powerful technology that offers new opportunities for pest control through silencing of genes that are essential for the survival of arthropod pests. The approach relies on sequence-specificity of applied double-stranded (ds)
J. Romeis, F. Widmer
semanticscholar +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, EarlyView.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source