Results 91 to 100 of about 5,242 (197)

Genomic and Morphological Insights Into the Adaptive Evolution of Honeybees in Rocky Desertification Habitats

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
Rocky desertification exerts significant selective pressures on honeybee morphology. Honeybees undergo adaptive evolution in 19 genes such as glycogen biosynthesis. Genes like GBE promote organismal survival under desertification. ABSTRACT Unlike traditional desertification, rocky desertification is a distinct form of land degradation characterized by ...
Yinglong Yu   +7 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, Volume 26, Issue 8, Page 9-28, August 2026.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Systematic Reanalysis of Whole‐Exome Sequencing in Genetically Unsolved Pediatric Primary Ciliary Dyskinesia

open access: yesPediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Background Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder, and despite advances in next‐generation sequencing, a substantial proportion of clinically suspected pediatric cases remain without a molecular diagnosis.
Tilbe Hakçıl Öz   +4 more
wiley   +1 more source

Shared and specific molecular mechanisms of proteasome inhibitors in chemotherapy‐induced peripheral neurotoxicity

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 5120-5147, August 2026.
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon   +27 more
wiley   +1 more source

Microtubules in Spinal Cord Injury: From Cytoskeletal Dysregulation to Therapeutic Regeneration

open access: yesJournal of Neurochemistry, Volume 170, Issue 8, August 2026.
Graphical illustration of the microtubule interactome following spinal cord injury as potential targets for therapy. ABSTRACT Spinal cord injury (SCI) triggers an immediate and sustained disruption of the composition and organization of the neuronal cytoskeleton.
Itzhak Fischer, Peter W. Baas
wiley   +1 more source

Genes Related to Sperm Motility Are Under Recent Ongoing Selection in Two Shorebird Species With a Polygynous Mating System and Frequent Multiple Paternity

open access: yesMolecular Ecology, Volume 35, Issue 15, August 2026.
ABSTRACT The analysis of the genomic architecture of selection can be insightful for the understanding of sexual conflict and sexual selection acting in wild populations. In general, there will be a wide range of possible targets of selection in the reproductive system of sexually promiscuous species.
Jakob C. Mueller, Bart Kempenaers
wiley   +1 more source

Range‐Wide Genetic Population Structure and Environmental Adaptation in the Eastern Oyster (Crassostrea virginica) Provides Insight for Aquaculture

open access: yesMolecular Ecology, Volume 35, Issue 15, August 2026.
ABSTRACT Selective breeding in aquaculture is necessary to establish food security and meet demand for sustainably produced protein. An informed selective breeding program requires understanding how population structure, environmental adaptation, and human activities shape natural genetic variation in wild conspecifics.
Madeline G. Eppley   +6 more
wiley   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science
Most Lepidopterans produce two distinct sperm types—nucleated eupyrene (fertile) and anucleate apyrene (non‐fertile), yet the genetic mechanisms governing this dimorphism remain poorly understood.
Hao Sun   +5 more
doaj   +1 more source

Molecular basis for assembly and activation of the Hook3 − KIF1C complex-dependent transport machinery

open access: yesEMBO Reports
Microtubule-associated cargo transport, a central process governing the localization and movement of various cellular cargoes, is orchestrated by the coordination of two types of motor proteins (kinesins and dyneins), along with diverse adaptor and ...
Hye Seon Lee   +6 more
doaj   +1 more source

Publisher Correction: Adaptor-mediated recruitment of three dyneins to dynactin enhances force generation. [PDF]

open access: yesNat Cell Biol
Rao L   +8 more
europepmc   +1 more source

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