Nonlinear amplitude dynamics in flagellar beating [PDF]
The physical basis of flagellar and ciliary beating is a major problem in biology which is still far from completely understood. The fundamental cytoskeleton structure of cilia and flagella is the axoneme, a cylindrical array of microtubule doublets ...
David Oriola +2 more
doaj +1 more source
Partially functional outer arm dynein in a novel Chlamydomonas mutant expressing a truncated γ heavy chain [PDF]
The outer dynein arm of Chlamydomonas flagella contains three heavy chains (α, β, and γ), each of which exhibits motor activity. How they assemble and cooperate is of considerable interest.
Kamiya Ritsu +7 more
core +2 more sources
Dynein Swings into Action [PDF]
Motor proteins, such as dynein, use chemical energy from ATP hydrolysis to move along the cytoskeleton. Roberts et al. (2009) now describe the arrangement of subdomains in the motor domain of dynein and propose a model for how these regions function together in force generation.
Houdusse, Anne, Carter, Andrew P.
openaire +2 more sources
In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley +1 more source
Connecting two arrays: The emerging role of actin-microtubule cross-linking motor proteins
The cytoskeleton of plant cells, consisting of actin filaments (AFs) and microtubules (MTs), is a central structure for various intracellular processes, such as cell division, isotropic and polar growth, vesicle transport, cell shape and morphogenesis ...
René eSchneider, Staffan ePersson
doaj +1 more source
Association of a 66 kDa Homolog of Chlamydomonas DC2, a Subunit of the Outer Arm Docking Complex, with Outer Arm Dynein of Sperm Flagella in the Ascidian Ciona intestinalis [PDF]
We previously identified a 66 kDa axonemal protein (Ci-Axp66.0) in sperm of the ascidian Ciona intestinalis. Here we found that Ci-Axp66.0 shows sequence similarity to the DC2 subunit of the Chlamydomonas outer arm docking complex.
Inaba Kazuo +6 more
core +1 more source
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source
Lissencephaly-1 is a context-dependent regulator of the human dynein complex
The cytoplasmic dynein-1 (dynein) motor plays a central role in microtubule organisation and cargo transport. These functions are spatially regulated by association of dynein and its accessory complex dynactin with dynamic microtubule plus ends. Here, we
Janina Baumbach +6 more
doaj +1 more source
Active transport of the ubiquitin ligase MID1 along the microtubules is regulated by protein phosphatase 2A. [PDF]
Mutations in the MID1 protein have been found in patients with Opitz BBB/G syndrome (OS), which is characterised by multiple malformations of the ventral midline.
Beatriz Aranda-Orgillés +5 more
doaj +1 more source
Molecular motors: design, mechanism and control
Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which synthesize ...
Chowdhury, Debashish
core +1 more source

