Results 11 to 20 of about 5,717 (230)
Ciliary Dyneins and Dynein Related Ciliopathies [PDF]
Cells, 2021 Although ubiquitously present, the relevance of cilia for vertebrate development and health has long been underrated. However, the aberration or dysfunction of ciliary structures or components results in a large heterogeneous group of disorders in ...
Dinu Antony +2 more
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Current Opinion in Cell Biology, 2008 Recent advances in our understanding of the axonemal dyneins reveal them to be much more complex than previously believed. A combination of genetic, molecular genetic, ultrastructural and biochemical approaches is now aiding the elucidation of the ...
Witman, George B.
core +4 more sources
Structure and Function of Dynein’s Non-Catalytic Subunits [PDF]
CellsDynein, an ancient microtubule-based motor protein, performs diverse cellular functions in nearly all eukaryotic cells, with the exception of land plants.
Lu Rao, Arne Gennerich
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Post-LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor. [PDF]
Cytoskeleton (Hoboken)ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
King SM.
europepmc +2 more sources
Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami
eLife, 2022 Bending of cilia and flagella occurs when axonemal dynein molecules on one side of the axoneme produce force and move toward the microtubule (MT) minus end.
Shimaa A Abdellatef +10 more
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Torque generating properties of Tetrahymena ciliary three-headed outer-arm dynein
Scientific Reports, 2022 Eukaryotic cilia/flagella are cellular bio-machines that drive the movement of microorganisms. Molecular motor axonemal dyneins in the axoneme, which consist of an 9 + 2 arrangement of microtubules, play an essential role in ciliary beating.
Shin Yamaguchi +2 more
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Predicting the locations of force-generating dyneins in beating cilia and flagella
Frontiers in Cell and Developmental Biology, 2022 Cilia and flagella are slender cylindrical organelles whose bending waves propel cells through fluids and drive fluids across epithelia. The bending waves are generated by dynein motor proteins, ATPases whose force-generating activity changes over time ...
Jonathon Howard +7 more
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Dynein and dynein-related genes [PDF]
Cell Motility and the Cytoskeleton, 1998 Dyneins are large, multisubunit ATPases that interact with microtubules to generate force. Dyneins move eukaryotic cilia and flagella and are in the cytoplasm, where they are involved in the transport of particles and organelles along microtubules and in the transport of condensed chromosomes during mitosis [reviewed in Holzbaur et al., 1994; Gibbons ...
openaire +3 more sources
The Generation of Dynein Networks by Multi-Layered Regulation and Their Implication in Cell Division
Frontiers in Cell and Developmental Biology, 2020 Cytoplasmic dynein-1 (hereafter referred to as dynein) is a major microtubule-based motor critical for cell division. Dynein is essential for the formation and positioning of the mitotic spindle as well as the transport of various cargos in the cell.
Takayuki Torisawa +3 more
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