Results 31 to 40 of about 824 (196)

Cytoplasmic dynein nomenclature [PDF]

The Journal of Cell Biology, 2005
A variety of names has been used in the literature for the subunits of cytoplasmic dynein complexes. Thus, there is a strong need for a more definitive consensus statement on nomenclature. This is especially important for mammalian cytoplasmic dyneins, many subunits of which are encoded by multiple genes.
Pfister, K. Kevin, Fisher, Elizabeth M. C., Gibbons, Ian R., Hays, Thomas S., Holzbaur, Erika L. F., McIntosh, J. Richard, Porter, Mary E., Schroer, Trina A., Vaughan, Kevin T., Witman, George B., King, Stephen M., Vallee, Richard B.   +11 more
openaire   +3 more sources

Nanoparticle-assisted optical tethering of endosomes reveals the cooperative function of dyneins in retrograde axonal transport [PDF]

, 2015
Dynein-dependent transport of organelles from the axon terminals to the cell bodies is essential to the survival and function of neurons. However, quantitative knowledge of dyneins on axonal organelles and their collective function during this long ...
Cui, Bianxiao, Che, Daphne L., Bawendi, Moungi, Pu, Kanyi, Chowdary, Praveen D., Kaplan, Luke, Chen, Ou, Bawendi, Moungi G.   +7 more
core   +1 more source

Inner lumen proteins stabilize doublet microtubules in cilia and flagella

Nature Communications, 2019
Microtubules in cilia are sufficiently stable to withstand the beating motion, but how they are stabilized while serving as tracks for intraflagellar transport and axonemal dyneins remains unknown.
Mikito Owa, Takayuki Uchihashi, Haru-aki Yanagisawa, Takashi Yamano, Hiro Iguchi, Hideya Fukuzawa, Ken-ichi Wakabayashi, Toshio Ando, Masahide Kikkawa   +8 more
doaj   +1 more source

Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule

eLife, 2019
Dyneins are motor proteins responsible for transport in the cytoplasm and the beating of axonemes in cilia and flagella. They bind and release microtubules via a compact microtubule-binding domain (MTBD) at the end of a coiled-coil stalk.
Samuel E Lacey, Shaoda He, Sjors HW Scheres, Andrew P Carter   +3 more
doaj   +1 more source

Functional State of the Axonemal Dyneins during Flagellar Bend Propagation [PDF]

, 2002
When mouse spermatozoa swim in media of high viscosity, additional waves of bending are superimposed on the primary traveling wave. The additional (secondary) waves are relatively small in scale and high in frequency.
Vernon, G.G., Woolley, D.M.
core   +1 more source

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility [PDF]

, 2017
A key player in the intracellular trafficking network is cytoplasmic dynein, a protein complex that transports molecular cargo along microtubule tracks. It has been shown that vertebrate dynein’s movement becomes strikingly enhanced upon interacting with
Gabriel C. Lander, McKenney, Richard J, Richard J. McKenney, Trina A. Schroer, Chowdhury, Saikat, Xu, Yiru, Yiru Xu, Lander, Gabriel C, Saikat Chowdhury, Schroer, Trina A, Danielle A. Grotjahn, Grotjahn, Danielle A   +11 more
core   +1 more source

Network of axonemal dyneins.

, 2012
(A) Dynein network: The green coloring indicates 4 out of 5 hits regarding axonemal dyneins. DNAH7 (also identified in our screen) was not part of the network. Blue symbols represent dyneins which were part of the library but were not determined as hits.
Ursula Holtzmann (180882), Horst Wenck (180890), Elke Grönniger (180886), Elma Smailbegovic (180878), Nikolaus Machuy (180874), Marc Winnefeld (180897), Franz Stäb (180894), Jörn Söhle (180871)   +7 more
core   +1 more source

Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that connects radial spoke 3 to dynein g and the nexin link.

PLoS Genetics, 2021
Ciliary beating requires the coordinated activity of numerous axonemal complexes. The protein composition and role of radial spokes (RS), nexin links (N-DRC) and dyneins (ODAs and IDAs) is well established.
Rafał Bazan, Adam Schröfel, Ewa Joachimiak, Martyna Poprzeczko, Gaia Pigino, Dorota Wloga   +5 more
doaj   +1 more source

Axonemal dyneins and force generation by neurons in Drosophila melanogaster ear [PDF]

, 2013
Analogous to vertebrate hair cells, the mechanosensory cilia of Drosophila auditory neurons are motile and serve dual, transducing and actuating roles.
Karak, Somdatta
core   +1 more source

Chlamydomonas DYX1C1/PF23 is essential for axonemal assembly and proper morphology of inner dynein arms.

PLoS Genetics, 2017
Cytoplasmic assembly of ciliary dyneins, a process known as preassembly, requires numerous non-dynein proteins, but the identities and functions of these proteins are not fully elucidated.
Ryosuke Yamamoto, Jagan M Obbineni, Lea M Alford, Takahiro Ide, Mikito Owa, Juyeon Hwang, Takahide Kon, Kazuo Inaba, Noliyanda James, Stephen M King, Takashi Ishikawa, Winfield S Sale, Susan K Dutcher   +12 more
doaj   +1 more source