Results 101 to 110 of about 12,362 (197)
Mycoses, Volume 69, Issue 2, February 2026.ABSTRACT Background Candida (Candidozyma) auris is an emerging yeast that poses a significant global health threat due to its multidrug resistance and ability to cause healthcare‐associated outbreaks. Genomic surveillance is essential for monitoring spread, transmission and antifungal resistance.
Luiz Marcelo Ribeiro Tomé +19 more
wiley +1 more source
Review on Current Status of Echinocandins Use
Antibiotics, 2020 Fungal infections are rising all over the world every year. There are only five medical compound classes for treatment: triazoles, echinocandins, polyenes, flucytosine and allylamine.
Martyna Mroczyńska +1 more
doaj +1 more source
Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis [PDF]
, 2017 The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds.
Ana C. A. de Paula e Silva +8 more
core +1 more source
Mycoses, Volume 69, Issue 2, February 2026.ABSTRACT Background Invasive candidiasis (IC), life‐threatening fungal infections with high economic burden, are often treated first‐line with daily intravenous echinocandins. A new once weekly echinocandin, rezafungin, demonstrated statistically non‐inferior efficacy and numerically shorter intensive care unit (ICU) stay compared to caspofungin in ...
Noemi Muszbek +10 more
wiley +1 more source
Two echinocandin-resistant Candida glabrata FKS mutants from South Africa
Medical Mycology Case Reports, 2016 Echinocandins are recommended as first-line agents to treat invasive infections caused by Candida glabrata since this organism is inherently less susceptible to azoles. However, resistance to echinocandins has been described in C. glabrata due to amino acid changes in the hotspot regions of the FKS1 and FKS2 genes. In this report, we describe the first
Serisha D. Naicker +6 more
openaire +3 more sources
Core histones govern echinocandin susceptibility in Candida glabrata
Microbiology SpectrumThe dynamic chromatin structure regulates many biological processes including gene expression, DNA repair, and genome stability in eukaryotic cells.
Aditi Pareek, Rupinder Kaur
doaj +1 more source
Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance. [PDF]
, 2016 The fungal pathogen Candida glabrata has emerged as a major health threat since it readily acquires resistance to multiple drug classes, including triazoles and/or echinocandins.
Alexander, B.D. +12 more
core +1 more source
Mycoses, Volume 69, Issue 2, February 2026.ABSTRACT Background Echinocandins are the first‐line treatment for invasive candidiasis. Rezafungin is a novel echinocandin with improved pharmacokinetic properties that allow for once‐weekly intravenous administration, offering potential advantages in complex clinical settings.
Jorge Boán +10 more
wiley +1 more source
Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and Pathogenesis. [PDF]
, 2014 Calcineurin signaling plays diverse roles in fungi in regulating stress responses, morphogenesis and pathogenesis. Although calcineurin signaling is conserved among fungi, recent studies indicate important divergences in calcineurin-dependent cellular ...
Juvvadi, P.R. +2 more
core +1 more source
Recent trends in molecular diagnostics of yeast infections : from PCR to NGS [PDF]
, 2019 The incidence of opportunistic yeast infections in humans has been increasing over recent years. These infections are difficult to treat and diagnose, in part due to the large number and broad diversity of species that can underlie the infection.
Arastehfar, A +26 more
core +2 more sources