Antimicrobial Activities and Mechanisms of Magnesium Oxide Nanoparticles (nMgO) against Pathogenic Bacteria, Yeasts, and Biofilms. [PDF]
, 2018 Magnesium oxide nanoparticle (nMgO) is a light metal based antimicrobial nanoparticle that can be metabolized and fully resorbed in the body. To take advantage of the antimicrobial properties of nMgO for medical use, it is necessary to determine the ...
Grelling, Nathaniel +4 more
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Treatment of Aspergillosis. [PDF]
, 2018 Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
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The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]
, 2017 N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda +215 more
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The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation [PDF]
, 2017 We thank Cowen lab members for helpful discussions. We also thank David Rogers (University of Tennessee) for sharing microarray analysis of the CAS5 homozygous mutant, and Li Ang (University of Macau) for assistance in optimizing the ChIP-Seq experiments.
Andrews, Brenda J +18 more
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Resistance to echinocandin-class antifungal drugs [PDF]
Drug Resistance Updates, 2007 Invasive fungal infections cause morbidity and mortality in severely ill patients, and limited drug classes restrict treatment choices. The echinocandin drugs are the first new class of antifungal compounds that target the fungal cell wall by blocking beta-1,3-d-glucan synthase.
openaire +2 more sources
Microbial Cell, 2022 The emergence of drug resistance significantly hampers the treatment of human infections, including those caused by fungal pathogens such as Candida species.
Pedro Pais +4 more
doaj +1 more source
Breakthrough Candidemia Due to Multidrug-Resistant Candida glabrata during Prophylaxis with a Low Dose of Micafungin [PDF]
, 2014 We identified a case of breakthrough candidemia in a 25-year-old patient receiving micafungin prophylaxis (50 mg/day). Five Candida glabrata isolates were obtained from blood cultures and were classified as multidrug-resistant isolates, since all of them
Bizerra, Fernando Cesar +6 more
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Abdominal Candidiasis Is a Hidden Reservoir of Echinocandin Resistance [PDF]
Antimicrobial Agents and Chemotherapy, 2014 ABSTRACT FKS mutant Candida isolates were recovered from 24% (6/25) of abdominal candidiasis patients exposed to echinocandin. Candida glabrata (29%) and Candida albicans (14%) mutants were identified.
Ryan K, Shields +3 more
openaire +2 more sources
Candida auris, what do paediatricians need to know? [PDF]
, 2018 AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
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Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]
, 2015 The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia +2 more
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