Results 81 to 90 of about 12,362 (197)
Journal of Fungi, 2023 Whole-genome sequencing (WGS) was used to determine the molecular mechanisms of multidrug resistance for 10 serial Candida glabrata bloodstream isolates obtained from a neutropenic patient during 82 days of amphotericin B (AMB) or echinocandin therapy ...
Ha Jin Lim +13 more
doaj +1 more source
Candida infections, causes, targets and resistance mechanisms. Traditional and alternative antifungal agents [PDF]
, 2013 The genus Candida includes about 200 different species, but only a few species are human opportunistic pathogens and cause infections when the host becomes debilitated or immunocompromised. Candida infections can be superficial or invasive.
Leonardi, Darío +1 more
core +3 more sources
Clinical Outcomes of Intra‐Abdominal Candidiasis by Initial Antifungal Therapy
Mycoses, Volume 69, Issue 3, March 2026.ABSTRACT Background Intra‐abdominal candidiasis (IAC) is a severe and heterogeneous infection associated with significant morbidity and mortality. Objectives To evaluate outcomes of IAC according to initial antifungal therapy and to identify predictors of persistent infection and 30‐day mortality.
M. Albanell‐Fernández +6 more
wiley +1 more source
Histone deacetylase inhibition as an alternative strategy against invasive aspergillosis. [PDF]
, 2015 Invasive aspergillosis (IA) is a life-threatening infection due to Aspergillus fumigatus and other Aspergillus spp. Drugs targeting the fungal cell membrane (triazoles, amphotericin B) or cell wall (echinocandins) are currently the sole therapeutic ...
Juvvadi, P.R. +2 more
core +2 more sources
Mycoses, Volume 69, Issue 3, March 2026.ABSTRACT Background Fluconazole‐resistant Candida parapsilosis is a matter of concern. Objectives To investigate fluconazole resistance among Candida parapsilosis complex isolates from patients admitted to three Brazilian hospitals, and to characterise resistance mechanisms and clonal relatedness. Patients/Methods A total of 76 C.
Sarah Santos Gonçalves +9 more
wiley +1 more source
Antifungal Resistance and Genotyping of Clinical Candida parapsilosis Complex in Japan
Journal of Fungi, 2023 Non-albicans Candida infections have recently gained worldwide attention due to their intrinsic resistance to different antifungal agents and the limited therapeutic options for treating them.
Hazim O. Khalifa +2 more
doaj +1 more source
Mycoses, Volume 69, Issue 3, March 2026.ABSTRACT Background Candida species are common causes of nosocomial infections. Candida parapsilosis has emerged as an important pathogen. Mortality rates associated with invasive C. parapsilosis infections range from 14.5% to 47%, with azole resistance estimated between 4% and 15%.
María de Lourdes García‐Hernández +16 more
wiley +1 more source
Acquired resistance to echinocandins in Candida albicans: case report and review [PDF]
Journal of Antimicrobial Chemotherapy, 2007 A patient with Candida albicans thrush and oesophagitis was treated with high doses of caspofungin but treatment eventually failed. Four C. albicans isolates were serially recovered before and after caspofungin treatment. A microbiological study was performed to characterize these four isolates.In vitro antifungal susceptibility testing was performed ...
Baixench, Marie-Thérèse +7 more
openaire +4 more sources
PLoS Genetics, 2016 Fungal pathogens have evolved diverse strategies to sense host-relevant cues and coordinate cellular responses, which enable virulence and drug resistance.
Elizabeth J Polvi +8 more
doaj +1 more source
Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection [PDF]
, 2018 This work was supported by the National Institutes of Health (R01AI080275 and R21AI22352), the NIH Fogarty International Center (R25TW009345), the University of Minnesota Center for Translational Science Institute (UL1TR000114), Wellcome Trust (086827 ...
Gow, Neil A R +5 more
core +1 more source