Results 121 to 130 of about 363,972 (179)

UVB-induced eIF2α phosphorylation in keratinocytes depends on decreased ATF4, GADD34 and CReP expression levels. [PDF]

Life Sci, 2021
Bahamondes Lorca VA, Bastidas Mayorga BD, Tong L, Wu S.   +3 more
europepmc   +1 more source

Alphaviruses are unique in allowing PKR activation and eIF2α phosphorylation in infected cells.

, 2013
A) Susceptibility of MEFs to viruses used in this study. Cells were infected with the indicated viruses to a moi of 25 pfu/cell and 6 h later pulsed with [35S]-Met for 30 min. Labeled proteins were resolved by SDS-PAGE followed of autoradiography. B) PKR
José Luis Nájera (5649529), Mariano Esteban (50256), Elena Domingo-Gil (356529), René Toribio (356530), Iván Ventoso (125168)   +4 more
core   +1 more source

Phosphorylation of eIF2α induced by EGFR inhibitors was independent of EGFR inhibitory effect.

, 2015
Effects of EGFR knockdown on eIF2α phosphorylation and alteration of cyclin-D1 levels induced by gefitinib and erlotinib were investigated. A549 cells were transfected with 50 pmol of siRNA against EGFR or control siRNA for 48 h before treated with ...
Atsushi Yonezawa (784929), Shunsaku Nakagawa (430323), Ikuko Yano (784930), Kazuo Matsubara (647154), Tomohiro Omura (784928), Takayuki Nakagawa (202988), Satoshi Imai (124356), Satoshi Koyama (784927)   +7 more
core   +1 more source

Fucoidan activates p-eIF2α\CHOP in MDA-MB-231 cells (A) and HCT116 cells (B).

, 2014
Cells were treated with fucoidan as described in the “Materials and Methods” and in Figure 2. The relative phosphorylation of eIF2α (p-eIF2α/eIF2α) and CHOP expression were remarkably increased by fucoidan as assessed by immunoblot. TG treatment (2.0 µM,
Yang Zhao (39052), Yu Zhang (12946), Daohai Zhang (79470), Shaohua Chen (114324)   +3 more
core   +1 more source

Mechanical stimulation suppresses phosphorylation of eIF2α and PERK-mediated responses to stress to the endoplasmic reticulum

, 2010
Cellular perturbations such as stress to the endoplasmic reticulum induce an integrated stress response, which activates phosphorylation of eIF2α and leads to alleviation of cellular injury or apoptosis.
Jiang, Chang, Zhang, Ping, Hirasawa, Hideyuki, Yang, Feng-Chun, Yokota, Hiroki   +4 more
core   +1 more source

Origin of translational control by eIF2α phosphorylation: insights from genome-wide translational profiling studies in fission yeast. [PDF]

Curr Genet, 2021
Asano K.
europepmc   +1 more source

Guanabenz Downregulates Inflammatory Responses via eIF2α Dependent and Independent Signaling

, 2016
Integrated stress responses (ISR) may lead to cell death and tissue degeneration via eukaryotic translation initiation factor 2 α (eIF2α)-mediated signaling.
Andy Chen, Bai-Yan Li, Akihiro Sudo, Chen, Andy, Yokota, Hiroki, Shengzhi Liu, Takigawa, Shinya, Liu, Shengzhi, Hamamura, Kazunori, Kazunori Hamamura, Li, Bai-Yan, Shinya Takigawa, Hiroki Yokota, Nishimura, Akinobu, Sudo, Akihiro, Akinobu Nishimura   +15 more
core   +1 more source

생쥐 웅성생식세포에서 eIF2α kinases 발현연구 [PDF]

, 2013
학위논문 (석사)-- 서울대학교 대학원 : 생명과학부, 2013. 2. 이건수.The mammalian male germ cells should be maintained below the core body temperature for their successful development.
박교선
core  

Brain-specific suppression of AMPKα2 isoform impairs cognition and hippocampal LTP by PERK-mediated eIF2α phosphorylation. [PDF]

Mol Psychiatry, 2021
Yang W, Zhou X, Zimmermann HR, Ma T.
europepmc   +1 more source

Roles of the Translation Initiation Factor eIF2α Phosphorylation in Cell Structure and Function. [PDF]

Cell Struct Funct, 2020
Back SH.
europepmc   +1 more source