Results 71 to 80 of about 3,553 (153)

Diversification of substrate specificities in teleostei Fads2: characterization of Δ4 and Δ6Δ5 desaturases of Chirostoma estor[S]

open access: yesJournal of Lipid Research, 2014
Currently existing data show that the capability for long-chain PUFA (LC-PUFA) biosynthesis in teleost fish is more diverse than in other vertebrates.
Jorge Fonseca-Madrigal   +5 more
doaj   +1 more source

Stimulating proteasomal degradation in human proteinopathies

open access: yesThe FEBS Journal, Volume 293, Issue 18, Page 5514-5540, September 2026.
The proteasome mediates the degradation of a wide range of proteins. Boosting proteasomal degradation may be beneficial in several disease contexts and can be achieved either by modulating proteasome activity or by improving substrate delivery. Proteasome activity can be enhanced by increasing proteasome abundance, inducing constitutive gate opening ...
Maria E. Gierisch   +2 more
wiley   +1 more source

Systems‐Level Plant Responses Reveal Pseudomonas‐Mediated Growth Promotion in Brachypodium Under Nitrogen Limitation

open access: yesPlant, Cell &Environment, Volume 49, Issue 9, Page 6396-6412, September 2026.
ABSTRACT Plant growth–promoting bacteria can enhance plant performance under nutrient limitation, yet the underlying plant molecular responses remain incompletely resolved. We investigated growth promotion by Pseudomonas koreensis in Brachypodium distachyon under contrasting nitrogen (N) regimes using time‐resolved phenotyping, elemental analysis ...
Stefan Sanow   +12 more
wiley   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing   +9 more
wiley   +1 more source

Data from: Divergence of cuticular hydrocarbons in two sympatric grasshopper species and the evolution of fatty acid synthases and elongases across insects

open access: yes, 2016
Cuticular hydrocarbons (CHCs) play a major role in the evolution of reproductive isolation between insect species. The CHC profiles of two closely related sympatric grasshopper species, Chorthippus biguttulus and C.
Geiselhardt, Sven   +4 more
core   +1 more source

Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies[S]

open access: yesJournal of Lipid Research, 2010
Ceramides (Cers) are important in embryogenesis, but no comprehensive analysis of gene expression for Cer metabolism nor the Cer amounts and subspecies has been conducted with an often used model: mouse embryonic stem cells (mESCs) versus embroid bodies (
Hyejung Park   +6 more
doaj   +1 more source

Conservation of desaturase and elongases in a Brazilian freshwater carnivorous teleost: The red piranha (Pygocentrus nattereri)

open access: yesBoletim do Instituto de Pesca
The endogenous biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFAs) in fish is species specific and depends on several factors, such as trophic level, feeding habits, environmental characteristics, taxonomic position and mainly the ...
Karine Vasconcelos Costa   +4 more
doaj   +1 more source

Functional characterization of the chicken fatty acid elongases

open access: yes, 2013
Data source: Supplemental Material, http://jn.nutrition.org/content/suppl/2012/12/21/jn.112.17029The health benefits of the (n-3) PUFA, EPA, and DHA have created a demand for fish and fish oil, the main sources of these PUFA.
Michael J. James   +7 more
core   +1 more source

Mitochondrial lipidome's fatty acid profile and peroxidation index are programmed tissue-specific traits

open access: yesRedox Biology
Mitochondria are dynamic systems adapted to the different cellular demands. In this context, it is hypothesized that lipids, and particularly fatty acids, are also affected by these adaptations and supported at transcriptional level.
Natàlia Mota-Martorell   +7 more
doaj   +1 more source

Desaturases and elongases, their diagnostic signifikance and determination of their avtivity

open access: yes, 2017
Předložená bakalářská práce se zabývá významem desaturáz a elongáz v metabolismu mastných kyselin. Jsou zde popsány mechanismy regulace a rozdělení těchto enzymů.
Křehlík, David
core   +1 more source

Home - About - Disclaimer - Privacy