Results 81 to 90 of about 3,553 (153)

Elovl4 and Fa2h expression during rat spermatogenesis: a link to the very-long-chain PUFAs typical of germ cell sphingolipids[S]

Journal of Lipid Research, 2018
The sphingolipids (SLs) of rodent spermatogenic cells (spermatocytes, spermatids) and spermatozoa contain nonhydroxylated and 2-hydroxylated versions of very-long-chain (C26–C32) PUFAs (n-V and h-V, respectively) not present in Sertoli cells (SCs). Here,
Florencia X. Santiago Valtierra, Daniel A. Peñalva, Jessica M. Luquez, Natalia E. Furland, Claudia Vásquez, Juan G. Reyes, Marta I. Aveldaño, Gerardo M. Oresti   +7 more
doaj   +1 more source

DE NOVO FATTY ACID SYNTHESIS BY MICROSOMAL ELONGASES IN TRYPANOSOMES

, 2006
Fatty acids (FAs) up to palmitate (C16) are made de novo by type I synthases in mammals and fungi. Bacteria and plants use type II synthases to make up to stearate (C18).
Lee, SooHee
core  

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival

International Journal of Biological Sciences, 2007
Mutations in the gene ELOVL4 have been shown to cause stargardt-like macular dystrophy. ELOVL4 is part of a family of fatty acid elongases and is yet to have a specific elongase activity assigned to it.
D. Joshua Cameron , Zongzhong Tong , Zhenglin Yang , Jack Kaminoh , Shin Kamiyah , Haoyu Chen , Jiexi Zeng , Yali Chen , Ling Luo , Kang Zhang
doaj  

Global triazine herbicide pollution impairs marine phytoplankton nutrition through disruption of acetyl-CoA-related metabolism

Ecotoxicology and Environmental Safety
Herbicide contamination impairs marine primary productivity, yet its subcellular impact on phytoplankton carbon allocation remains poorly understood.
Qingyue Shen, Jiawang Zhao, Xiaotong He, Liqiang Yang   +3 more
doaj   +1 more source

Function of desaturases and elongases in human lipid metabolismus

, 2013
Tato bakalářská práce se zabývá funkcí desaturáz a elongáz v metabolismu lipidů člověka. Zkoumá jejich význam v metabolismu endogenních a exogenních mastných kyselin na příkladu laboratorních zvířat i člověka.
Mastíková, Anna
core   +1 more source

Genetic variation in fatty acid elongases is not associated with intermediate cardiovascular phenotypes or myocardial infarction

, 2019
BACKGROUND/OBJECTIVES: Elongases 2, 4 and 5, encoded by genes ELOVL2, ELOVL4 and ELOVL5, have a key role in the biosynthesis of very long chain polyunsaturated fatty acids (PUFAs).
Deka, R., Linkletter, C. D., Ordovas, J. M., Baylin, A., Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600, Aslibekyan, S., Jensen, M. K., Campos, H., Loucks, E. B.   +8 more
core   +1 more source

Very long-chain fatty acids accumulate in breast cancer tissue and serum

Cancer Cell International
Background Breast cancer (BC) remains one of the most common cancers with relatively high mortality and is associated with alterations in fatty acid (FA) metabolism.
Alicja Pakiet, Michalina Ciosek, Oliwia Lange, Katarzyna Duzowska, Agata Janczy, Małgorzata Kapusta, Yelyzaveta Razghonova, Marcin Ekman, Anna Abacajew-Chmyłko, Paweł Kabata, Adriana Mika   +10 more
doaj   +1 more source

Cuticle Maturation in Apis mellifera: Cuticular Hydrocarbons Profiles, Expression and Evolution of Desaturases and Elongases.

, 2013
Os hidrocarbonetos cuticulares têm importante papel no processo de reconhecimento dos membros da colônia de insetos sociais. Muitos estudos têm mostrado variações qualitativas e quantitativas nestes compostos entre os insetos adultos. Contudo, abordagens
Lopes, Tiago Falcon, Tiago Falcon Lopes
core   +1 more source

X-linked adrenoleukodystrophy: current aspects of dietary therapy (narrative review)

Клинический разбор в общей медицине
X-linked adrenoleukodystrophy (X-ALD) is a rare genetically determined peroxisomal disorder caused by mutations in the ABCD1 gene, characterized by progressive accumulation of saturated very long-chain fatty acids (VLCFAs, C26:0) in cells.
Fatima Kh. Dzgoeva, Tatyana E. Borovik, Tatyana E. Borovik, Anastasiia N. Azovtseva, Natalia V. Silina, Sabina E. Mingacheva, Anastasiia V. Zuikova, Madina А. Chabieva   +7 more
doaj   +1 more source