Results 171 to 180 of about 83,738 (273)

Asymmetric [3,3]‐Sigmatropic Rearrangement for the Synthesis of Quaternary Center‐Containing Polycyclic Molecules: Application to the Total Synthesis of Myrmenaphthol A

ChemistryEurope, EarlyView.
A small library of tricyclic natural product‐like molecules with quaternary stereocenters is rapidly synthesized. An excellent chirality transfer from sulfur to carbon atom is observed, furnishing the desired products in 90–99% enantiomeric excesses and 51–78% isolated yields.
Weiping Zhou, Gia Hao Huynh, Arnaud Voituriez   +2 more
wiley   +1 more source

Biocatalytic kinetic resolution for efficient and enantioselective synthesis of δ-haloalcohols and tetrahydrofurans. [PDF]

Commun Chem
Wang YF, Hua X, Wang ZY, Jin X, Wang HH, Chen YZ, Wan NW.   +6 more
europepmc   +1 more source

Correction: A highly enantioselective Biginelli reaction using self-assembled methanoproline–thiourea organocatalysts: asymmetric synthesis of 6-isopropyl-3,4-dihydropyrimidines

, 2016
Zhijun Hang, Junwu Zhu, Xiang Lian, Peng Xu, Han Yu, Sheng Han   +5 more
openalex   +2 more sources

Copper‐Catalyzed Defluorinative Allylboration of Allenes with Trifluoromethyl Alkenes

ChemistryEurope, EarlyView.
A copper‐catalyzed borylative coupling of allenes with 1‐trifluoromethyl alkenes is reported. The reaction selectively provides synthetically versatile borylated 1,1‐difluoro‐1,5‐dienes that can be converted into a range of medicinally relevant fluorinated compounds. Mechanistic studies reveal a key role of the catalytically generated LiCl by assisting
Martín Piñeiro‐Suárez, Hugo Jiménez‐Cristóbal, Israel Fernández, Martín Fañanás‐Mastral   +3 more
wiley   +1 more source

Chiral heterogeneous photocatalysts for enantioselective synthesis: standing on the shoulders of organocatalysis. [PDF]

Chem Sci
Callegari C, Moroni M, Ravelli D, Malavasi L.   +3 more
europepmc   +1 more source

Enantioselective Total Synthesis of (+)-Isoboonein.

, 1998
Masahiro Tada, S. Inoue, Takao Miki, Shin‐ichi Onogi, Jun‐ichi Kaminaga, Junko Hiraoka, Yoshikazu Kitano, Kazuhiro Chiba   +7 more
openalex   +2 more sources

Photoinduced Boron‐Catalyzed Direct α‐Aminoxylation of Carboxylic Acids

ChemistryEurope, EarlyView.
A boron‐catalyzed α‐aminoxylation of carboxylic acids enables rapid access to sterically congested α‐(aminoxy)carboxylic acids. Photoexcited diboron enediolates transfer energy to O‐sulfonylhydroxylamines, triggering SO bond cleavage to generate N‐oxyl radicals.
Tsubasa Oyama, Takuto Morisawa, Yukiho Yoshida, Yoshito Heike, Masaya Sawamura, Yohei Shimizu   +5 more
wiley   +1 more source

Catalytic Enantioselective Synthesis of Oxazolines with Vinylogous Isocyano Esters. [PDF]

Org Lett
Guzmán-Cedillo C, Monleón-Ventura A, Sanz-Marco A, Vila C, Blay G.   +4 more
europepmc   +1 more source

Synthesis of Coupling Substrates for Use in a Highly Enantioselective Conjugated Triene Cyclization Enabled by a Chiral N-Heterocyclic Carbene

, 2022
Christopher Toth
openalex   +2 more sources

CuH‐Catalyzed Asymmetric Desymmetrization of Cyclobutenes via Stereodivergent Hydroamination

ChemistryEurope, EarlyView.
The CuH‐catalyzed stereodivergent hydroamination through asymmetric desymmetrization of cyclobutenes has been achieved, yielding a range of trisubstituted aminocyclobutanes with excellent results. A series of subsequent transformations, including the first asymmetric synthesis of two pharmaceutically active molecules, have been realized, and density ...
Xiang Lei, Peng Luo, Shouang Lan, Wennan Dong, Chao Xu, Jinggong Liu, Shuang Yang, Qi Zhang, Xinqiang Fang   +8 more
wiley   +1 more source