Results 31 to 40 of about 3,265,586 (282)
Beilstein Journal of Organic Chemistry, 2013 A concise enantioselective synthesis of the advanced intermediate 5 for the synthesis of pumiliotoxins (Gallagher’s intermediate) is described. The synthesis started from the regio- and trans-diastereoselective (dr = 98:2) reductive 3-butenylation of (R)-
Jie Zhang +2 more
doaj +1 more source
Enantioselective Synthesis of cis-Decalins Using Organocatalysis and Sulfonyl Nazarov Reagents
Molecules, 2015 The first organocatalytic synthesis of cis-decalins using sulfonyl Nazarov reagents is reported. The Jørgensen’s catalyst directs this highly enantioselective synthesis using different cyclohexenal derivatives.
Javier Peña +6 more
doaj +1 more source
Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]
, 2008 Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T. +5 more
core +2 more sources
Chromium(II)-catalyzed enantioselective arylation of ketones
Beilstein Journal of Organic Chemistry, 2016 The chromium-catalyzed enantioselective addition of carbo halides to carbonyl compounds is an important transformation in organic synthesis. However, the corresponding catalytic enantioselective arylation of ketones has not been reported to date. Herein,
Gang Wang +4 more
doaj +1 more source
Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]
, 2016 This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima +4 more
core +1 more source
Total Enantioselective Synthesis of (‐)‐Cytisine. [PDF]
ChemInform, 2004 [reaction: see text] The first total enantiosynthesis of the biologically active alkaloid (-)-cytisine is reported, featuring a ruthenium-catalyzed RCM reaction as the key step. The approach relies on readily available cis-piperidine-3,5-dimethanol monoacetate as the chiral building block, and it is suited for achieving the target compound in both ...
B. Danieli +5 more
openaire +6 more sources
Molecules, 2006 The enantioselective synthesis of the title compound, using Meyers' bicyclic lactam methodology, is described. This compound and a few of its derivatives are useful intermediates in natural product synthesis.
Pierre J. De Clercq +2 more
doaj +1 more source
Biologically active Phytophthora mating hormone prepared by catalytic asymmetric total synthesis [PDF]
, 2008 A Phytophthora mating hormone with an array of 1,5-stereogenic centers has been synthesized by using our recently developed methodology of catalytic enantioselective conjugate addition of Grignard reagents. We applied this methodology in a diastereo- and
A. J. Minnaard +23 more
core +4 more sources
Enantioselective Total Synthesis of Macfarlandin C, a Spongian Diterpenoid Harboring a Concave-Substituted cis-Dioxabicyclo[3.3.0]octanone Fragment. [PDF]
, 2020 The enantioselective total synthesis of the rearranged spongian diterpenoid (-)-macfarlandin C is reported. This is the first synthesis of a rearranged spongian diterpenoid in which the bulky hydrocarbon fragment is joined via a quaternary carbon to the ...
Allred, Tyler K +4 more
core +2 more sources
Influence of Phosphoramidites in Copper-Catalyzed Conjugate Borylation Reaction [PDF]
, 2012 Copper(I) has become the preferred metal to catalyze the β-boration of α,β-unsaturated carbonyl compounds, and now we demonstrate that easily accessible monodentate chiral ligands, such as phosphoramidites and phosphites, can be convenient alternative ...
Bonet, Amadeu, +6 more
core +4 more sources