Enantioselective Organocatalytic Diels-Alder Trapping of Photochemically Generated Hydroxy-o-Quinodimethanes [PDF]
, 2016 The photoenolization/Diels-Alder strategy offers straightforward access to synthetically valuable benzannulated carbocyclic products. This historical light-triggered process has never before succumbed to efforts to develop an enantioselective catalytic ...
Cuadros, Sara +3 more
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Enantioselective Total Synthesis of (−)‐Diversonol
Chemistry – A European Journal, 2013 AbstractFor the synthesis of (−)‐diversonol (ent‐1), an enantioselective domino‐Wacker/carbonylation/methoxylation reaction and an enantioselective Wacker oxidation were used to give the chroman in high yield and 96 % and 93 % ee, respectively. Dihydroxylation at the vinyl moiety using the Sharpless procedure and a Wittig–Horner reaction followed by ...
Tietze, Lutz Friedjan +5 more
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Enantioselective Total Synthesis of (+)‐Eucophylline
Chemistry – A European Journal, 2022 AbstractThe total enantioselective synthesis of (+)‐eucophylline 1 was achieved using as a key‐structural motif a chiral piperidinone bearing the natural product all‐carbon quaternary stereocenter. The elaboration of the latter is based on two strategies relying on the free‐radical carbo‐cyanation and sulfonyl‐cyanation respectively of enantiopure ...
Iman Traboulsi +4 more
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Catalytic synthesis of chiral sulfinimidate esters via oxidative esterification of sulfenamides
Nature CommunicationsAza-sulfur compounds, such as sulfilimines, sulfoximines, etc, are increasingly recognized as essential contributors to advancements in drug development and asymmetric synthesis.
Hua-Jie Jiang +8 more
doaj +1 more source
Nature Communications, 2017 Enantioselective synthesis of six-membered oxacycles with multiple stereogenic centres is essential for the discovery of new therapeutic agents. Here the authors show organocatalytic cycloetherification for the highly enantio- and diastereoselective ...
Naoki Yoneda +4 more
doaj +1 more source
Green Synthesis and Catalysis, 2021 Chiral α-amino-β2,2-amino acid is an ubiquitous fragment that presents in natural products, pharmaceuticals, and bioactive molecules. However, the catalytic enantioselective synthesis of α-amino-β2,2-amino acids with structural complexity and diversity ...
Xue Tian +4 more
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Molybdenum-catalyzed enantioselective sulfoxidation controlled by a nonclassical hydrogen bond between coordinated chiral imidazolium-based dicarboxylate and peroxido ligands [PDF]
, 2018 Chiral alkyl aryl sulfoxides were obtained by molybdenum-catalyzed oxidation of alkyl aryl sulfides with hydrogen peroxide as oxidant in mild conditions with high yields and moderate enantioselectivities.
Carrasco Carrasco, Carlos Jesús +2 more
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Recent advances in catalytic asymmetric synthesis
Frontiers in ChemistryAsymmetric catalysis stands at the forefront of modern chemistry, serving as a cornerstone for the efficient creation of enantiopure chiral molecules characterized by their high selectivity. In this review, we delve into the realm of asymmetric catalytic
Ashna Garg +5 more
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Asymmetric preparation of antifungal 1-(4 -chlorophenyl)-1-cyclopropyl methanol and 1-(4 -chlorophenyl)-2-phenylethanol. Study of the detoxification mechanism by Botrytis cinerea [PDF]
, 2011 Chiral alcohols are important as bioactive compounds or as precursors to such molecules. On the basis of the different antifungal properties of the enantiopure alcohol derivatives of 4-chlorophenyl cyclopropyl ketone and benzyl 4-chlorophenyl ketone ...
Aleu Casatejada, Josefina +4 more
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The effect of alcohol on the performance of lipase-immobilized enzymatic membrane reactor for esterification of (R,S)-ketoprofen [PDF]
, 2006 The effect of alcohols on the performance of lipase-immobilized enzymatic membrane reactor (EMR) for enantioselective esterification of (R,S)-ketoprofen has been studied. In this work, mixed solvent medium was used and the (R)-ketoprofen was reacted with
Bhatia, Subhash +3 more
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