Results 31 to 40 of about 39,817 (294)
Structural investigations of the regio- and enantioselectivity of lipases [PDF]
, 1998 Although lipases are widely applied for the stereospecific resolution of racemic mixtures of esters, the atomic details of the factors that are responsible for their stereospecificity are largely obscure. We determined the X-ray structures of Pseudomonas
Bando +38 more
core +2 more sources
On the Origins of Life's Homochirality: Inducing Enantiomeric Excess with Spin-Polarized Electrons [PDF]
Proc. Natl. Acad. Sci. U.S.A. 119 (2022), 2022 Life as we know it is homochiral, but the origins of biological homochirality on early Earth remain elusive. Shallow closed-basin lakes are a plausible prebiotic environment on early Earth, and most are expected to have significant sedimentary magnetite deposits.
arxiv +1 more source
Ferrocene-derived P,N ligands : synthesis and application in enantioselective catalysis [PDF]
, 2013 Due to their unique steric and electronic properties, air-stability and modular structure, chiral hybrid P,N-ferrocenyl ligands play a prominent role in the field of asymmetric catalysis.
Noël, Timothy, Van der Eycken, Johan
core +1 more source
Scientific Reports, 2017 Density functional M11 was used to study the mechanism and enantioselectivity of a binaphthophosphepine-catalyzed intramolecular [3 + 2] cycloaddition reaction.
Meng Duan +6 more
doaj +1 more source
Molecules, 2012 Catalytic asymmetric Corey-Chaykovsky epoxidation of various ketones with dimethyloxosulfonium methylide using a heterobimetallic La-Li3-BINOL complex (LLB) is described.
Shigeki Matsunaga +3 more
doaj +1 more source
Enhanced Production of (S)-2-arylpropionic Acids by Protein Engineering and Whole-Cell Catalysis
Frontiers in Bioengineering and Biotechnology, 2021 Esterases are important biocatalysts for chemical synthesis. Several bHSL family esterases have been used to prepare (S)-2-arylpropionic acids with stronger anti-inflammatory effects via kinetic resolution.
Xiaolong Liu +3 more
doaj +1 more source
On the definition of chirality and enantioselective fields [PDF]
Isr. J. Chem. 62, e202200049 (2022), 2022 In solid state physics, any symmetry breaking is known to be associated with emergence of an order parameter. However, the order parameter for molecular and crystal chirality, which is a consequence of parity and mirror symmetry breaking, has not been known since its discovery.
arxiv +1 more source
Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids [PDF]
, 2007 Herein, we report the automated parallel synthesis of solution-phase libraries of phosphoramidite ligands for the development of enantioselective catalysts.
Feringa, Ben L., +5 more
core +1 more source
Enhanced enantioselectivity in halogen-bonding catalysis
Communications Chemistry, 2023 Chiral halogen-bonding catalysts have emerged as a new approach towards asymmetric catalysis, but enantioselectivities have thus far remained low. Now, fine-tuning the substrate–catalyst halogen–halogen interactions is shown to significantly enhance ...
Victoria Richards
doaj +1 more source
Organocatalytic synthesis of axially chiral atropisomers [PDF]
, 2017 This review summarises the recent progress made in the organocatalytic synthesis of atropisomeric compounds. Methodologies based on dynamic kinetic resolution and direct access to BINOL-like biaryls are described.
Renzi, P.
core +1 more source