Results 91 to 100 of about 36,224 (218)

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion

Scientific Reports, 2020
There are currently no pharmacological approaches in fracture healing designed to therapeutically stimulate endochondral ossification. In this study, we test nerve growth factor (NGF) as an understudied therapeutic for fracture repair.
Kevin O. Rivera, Fabrizio Russo, Ryan M. Boileau, Ryan E. Tomlinson, Theodore Miclau, Ralph S. Marcucio, Tejal A. Desai, Chelsea S. Bahney   +7 more
doaj   +1 more source

Eagle's Syndrome Presenting With Peripheral Facial Palsy—A Case Report

Head &Neck, EarlyView.
ABSTRACT Background Eagle's syndrome is a condition caused by an elongated styloid process and is characterized by various symptoms such as cervicofacial pain, foreign body sensation, headache, odynophagia, and otalgia. However, the occurrence of a unilateral peripheral facial palsy as a symptom of Eagle's syndrome has been described only rarely ...
Vincent Holtmann, Roman Ackermann, Klaus Jahn, John‐Martin Hempel   +3 more
wiley   +1 more source

Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway

Bone Research
Piezo1, a key mechanosensor in bone homeostasis, plays a crucial role in fracture healing. However, the mechanisms through which Piezo1 regulates chondrocytes and affects endochondral ossification remain poorly understood. This study aimed to investigate
Tao Zhang, Hongzhi Lv, Siming Jia, Lijun Wang, Weijian Liu, Kai Ding, Xiaofeng Du, Guangzhao Hou, Zhiyong Hou, Yingze Zhang, Weiguo Zou, Wei Chen, Yanbin Zhu   +12 more
doaj   +1 more source

Biomaterial-based endochondral bone regeneration: a shift from traditional tissue engineering paradigms to developmentally inspired strategies

Materials Today Bio, 2019
There is an urgent, clinical need for an alternative to the use of autologous grafts for the ever increasing number of bone grafting procedures performed annually.
E.J. Sheehy, D.J. Kelly, F.J. O'Brien
doaj   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Effect of alendronate on endochondral ossification in mandibular condyles of growing rats

European Journal of Histochemistry, 2012
The replacement of the calcified cartilage by bone tissue during the endochondral ossification of the mandibular condyle is dependent of the resorbing activity of osteoclats.
V. Bradaschia-Correa, F.A.C. Barrence, L.B. Ferreira, L.F. Massa, V.E. Arana-Chavez   +4 more
doaj   +1 more source

A Role for the BMP Antagonist Chordin in Endochondral Ossification

Journal of Bone and Mineral Research, 2002
Abstract Bone morphogenetic proteins (BMPs) are ubiquitous regulators of cellular growth and differentiation. A variety of processes modulate BMP activity, including negative regulation by several distinct binding proteins. One such BMP antagonist chordin has a role in axis determination and neural induction in the early embryo.
Donghui, Zhang, Cristin M, Ferguson, Regis J, O'Keefe, J Edward, Puzas, Randy N, Rosier, Paul R, Reynolds   +5 more
openaire   +2 more sources

Dura mater‐preserving technique for fetal brain extraction after intrauterine death with prolonged retention

Journal of Forensic Sciences, EarlyView.
Abstract Examination of the fetal brain represents a crucial step in the diagnostic assessment of fetal death in utero, particularly in cases of unexplained intrauterine fetal death (IUFD). Prolonged intrauterine retention, advanced autolysis, and the intrinsic structural immaturity of the fetal brain frequently compromise tissue integrity, limiting ...
Ezio Fulcheri, Francesca Buffelli, Sharon Duzioni, Francesco Lupariello, Francesca Pesce, Valerio Gaetano Vellone, Alessandro Bonsignore   +6 more
wiley   +1 more source

Bone / Cartilage - Endochondral Ossification

The long bones develop by endochondral ossification, in which a cartilage model is laid down and then transformed into bone.
Gorski, Roger A.
core   +1 more source