Results 101 to 110 of about 36,224 (218)

Histological and Histomorphometric illustration the endochondral ossification of the mandibular angle defect repair in rats after oral stimulation with bisphosphonate treatment (an in vivo study)

Diyala Journal of Medicine
Background: Bio-phosphonates can be used to lower the risk of hip and spine fractures. Additionally, they can be used to treat Paget's disease of the bones in a variety of dosages.
Manar Abd Alrazaq Hassan,, Ansam Mahdi Khalel,, Asmaa A. Ajwad ,, Ali hakiem tawfieq   +3 more
doaj   +1 more source

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

Cell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen, Liangliang Liu, Xumeng Wang, Juanjuan Li, Jingyi Zhang, Xiaoli Shi, Qing Sun, Xu Chang, Jing Zhang, Jie Zhao, Fu Wang   +10 more
wiley   +1 more source

endochondral ossification

Citation: 'endochondral ossification' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10656 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
openaire   +1 more source

Neurodevelopmental and neurological features in children with hypochondroplasia

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To assess neurodevelopmental and neurological features, including neuroimaging abnormalities, in children with molecularly confirmed hypochondroplasia. Method A retrospective cohort study of children with molecularly confirmed hypochondroplasia seen at Evelina London Children's Hospital skeletal dysplasia service was performed.
Megan F. Baxter, Rhoda Akilapa, Alessandra Cocca, Melita D. Irving   +3 more
wiley   +1 more source

How do forelimb long bones adapt in rhinoceroses? An in‐depth examination of their microanatomy

Journal of Anatomy, EarlyView.
Here, we study the bone structure in the forelimb long bones of the five extant species of rhinoceroses. By combining traditional description of virtual sections made on the bones (A) with in‐depth cartographies of the variation of bone compactness and anisotropy (B), we show how bone tissue can adapt to extreme forces and constraints in the second ...
Cyril Etienne, Axel de Jesus, Vincent Fernandez, Alexandra Houssaye   +3 more
wiley   +1 more source

Trpv4-Mediated Mitophagy Regulates Endochondral Ossification In The Condylar Cartilage

International Dental Journal
Aim or purpose: This study aims to elucidate the mechanism by which mouth breathing-induced condylar stress change (MB-CSC) disrupts endochondral ossification in the posterior zone of condyle.
Fei Liu, Ying Zhao
doaj   +1 more source

Bone Grafts: Everything You Need to Know

Journal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen, Javier Sanz, Giuseppe Perale, Augustine Mark Saiz, Mario Romandini, Maryam Rahmati   +5 more
wiley   +1 more source

Biphasic biomimetic scaffolds based on a regionally decalcified bone framework and pre-chondrogenic microspheres for osteochondral defect repair

Materials Today Bio
Osteochondral defects are still facing a significant challenge in clinical surgery, making post-trauma repair difficult. Tissue engineering has provided a promising approach to solving these defects.
Zhuo Liang, Qingqing Pan, Fei Xue, Jingdi Zhang, Zhenlin Fan, Weiyun Wang, Xueqiang Guo, Zhuang Qian, Yaping Shen, Wenjuan Song, Lei Wang, Guangdong Zhou, Yong He, Wenjie Ren   +13 more
doaj   +1 more source

Cyclic Tensile Strain Can Play a Role in Directing both Intramembranous and Endochondral Ossification of Mesenchymal Stem Cells

Frontiers in Bioengineering and Biotechnology, 2017
Successfully regenerating damaged or diseased bone and other joint tissues will require a detailed understanding of how joint specific environmental cues regulate the fate of progenitor cells that are recruited or delivered to the site of injury.
Simon F. Carroll, Simon F. Carroll, Conor T. Buckley, Conor T. Buckley, Conor T. Buckley, Daniel J. Kelly, Daniel J. Kelly, Daniel J. Kelly, Daniel J. Kelly   +8 more
doaj   +1 more source

Myeloid A20 Regulates Periodontal Tissue Integrity and Temporomandibular Joint Structure

Journal of Periodontal Research, EarlyView.
Dysregulation of A20 signaling has been implicated in several immune‐mediated diseases, including rheumatoid arthritis and psoriasis, conditions characterized by excessive NF‐κB activation and inflammatory tissue damage. The structural alterations observed in this model suggest that impaired regulation of innate immune signaling may increase ...
Karol Alí Apaza Alccayhuaman, Patrick Heimel, Toni Dobsak, Stefan Tangl, Geert van Loo, Dieter D. Bosshardt, Reinhard Gruber   +6 more
wiley   +1 more source