Results 71 to 80 of about 18,079 (225)

Runx2 regulates endochondral ossification in condyle during mandibular advancement [PDF]

, 2005
Runx2 is a transcription factor prerequisite for chondrocyte maturation and osteoblast differentiation. We tested the hypothesis that Runx2 is responsible for signaling chondrocyte maturation and endochondral ossification in the condyle during mandibular
Rabie, ABM, Tang, GH
core   +1 more source

Anatomical Study and Classification of Foramina of the Squamous Part of the Temporal Bone

Clinical Anatomy, EarlyView.
ABSTRACT The postglenoid foramen (PGF) is a rarely reported anatomical variant of the temporal bone, with limited data on its morphology, prevalence, and clinical relevance, particularly in non‐European populations. This study aimed to investigate the anatomy and frequency of foramina located on the squamous part of the temporal bone, including the PGF,
Tawanrat Paensukyen, Pattita Kanjanapaisan, Napawan Taradolpisut, Nutmethee Kruepunga, Benrita Jitaree, Pakpoom Thintharua, Arada Chaiyamoon, Athikhun Suwannakhan   +7 more
wiley   +1 more source

HIF-1α as a Regulator of BMP2-Induced Chondrogenic Differentiation, Osteogenic Differentiation, and Endochondral Ossification in Stem Cells

Cellular Physiology and Biochemistry, 2015
Background/Aims: Joint cartilage defects are difficult to treat due to the limited self-repair capacities of cartilage. Cartilage tissue engineering based on stem cells and gene enhancement is a potential alternative for cartilage repair.
Nian Zhou, Ning Hu, Jun-Yi Liao, Liang-Bo Lin, Chen Zhao, Wei-Ke Si, Zhong Yang, Shi-Xiong Yi, Ting-Xu Fan, Wei Bao, Xi Liang, Xu Wei, Hong Chen, Cheng Chen, Qiang Chen, Xin Lin, Wei Huang   +16 more
doaj   +1 more source

Bone defect reconstruction via endochondral ossification: A developmental engineering strategy

Journal of Tissue Engineering, 2021
Traditional bone tissue engineering (BTE) strategies induce direct bone-like matrix formation by mimicking the embryological process of intramembranous ossification.
Rao Fu, Chuanqi Liu, Yuxin Yan, Qingfeng Li, Ru-Lin Huang   +4 more
doaj   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Detection of hypoxia inducible factors and angiogenic growth factors during foetal endochondral and intramembranous ossification

, 2010
During skeletogenesis, the development of a new vascular network, i.e. angiogenesis, is triggered by hypoxia through the activation of the hypoxia inducible factors (HIFs) HIF-1a and HIF-2a.
Cornillie, Pieter, P. Cornillie, W. De Spiegelaere, De Spiegelaere, Ward, Burvenich, Christian Paul G., W. Van den Broeck, Van Den Broeck, Wim, Casteleyn, Christophe, C. Burvenich, C. Casteleyn   +9 more
core   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Understanding tissue-engineered endochondral ossification; towards improved bone formation [PDF]

, 2019
Endochondral ossification (EO) is the process by which the long bones of the body form and has proven to be a promising method in tissue engineering for achieving cell-mediated bone formation.
C Kiernan, Farrell, E. (Eric), E Wolvius, E Farrell, Knuth, C., Wolvius, E.B. (Eppo), Wolvius, Eppo, Farrell, Eric, Kiernan, C, Kiernan, C., Narcisi, R. (Roberto), Knuth, C, C Knuth, Narcisi, Roberto, R Narcisi   +14 more
core   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

The impact of cartilage releasate on angiogenesis during endochondral ossification [PDF]

, 2023
Cartilage compared to other tissues has a relatively simple composition, which makes it an ideal tissue to try to reproduce in the laboratory. However, so far this goal is still out of reach.
Nossin, Yannick
core   +2 more sources