Results 71 to 80 of about 18,120 (213)

P15 peptide stimulates chondrogenic commitment and endochondral ossification [PDF]

, 2017
Purpose The synthetic 15 amino acid biomimetic peptide sequence (P15) derived from a region of the alpha (alpha)-1 chain of collagen I, has been shown to promote alpha 2 integrin activation and enhance intramembranous ossification.
Freeman, Theresa A., Fertala, Andrzej, Carol Diallo, Ozҫan Kaya, Kaya, Oz An, Eisenhauer, Peter, Jun Zhang, Andrzej Fertala, Diallo, Carol, Alexander R. Vaccaro, Peter Eisenhauer, Theresa A. Freeman, Vaccaro, Alexander R., Zhang, Jun   +13 more
core   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

Advanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma, Lucinda A. E. Evans, Lucie E. Bourne, Jishizhan Chen, Alissa L. Parmenter, Joseph Brunet, Kamel Madi, Sebastian Marussi, Andrew A. Pitsillides, Peter D. Lee, Katherine A. Staines   +10 more
wiley   +1 more source

Ontogeny of murine bony semicircular canal form

The Anatomical Record, EarlyView.
Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna, Nathan Jeffery   +1 more
wiley   +1 more source

ADAM17 Controls Endochondral Ossification by Regulating Terminal Differentiation of Chondrocytes [PDF]

, 2013
Endochondral ossification is a highly regulated process that relies on properly orchestrated cell-cell interactions in the developing growth plate. This study is focused on understanding the role of a crucial regulator of cell-cell interactions, the ...
Crawford, Howard C, Otero, Miguel, Selleri, Licia, Froemel, Dara, Plumb, Darren A, Boskey, Adele, Goldring, Mary B, Hill, Daniel, Maretzky, Thorsten, Blobel, Carl P, Hall, Katherine C, Dragomir, Cecilia L   +11 more
core   +1 more source

Cranial anatomy of a Late Cretaceous aspidorhynchid fish (Neopterygii: Aspidorhynchiformes) from Alberta, Canada

The Anatomical Record, EarlyView.
Abstract Belonostomus longirostrisis was named for an isolated jaw fragment from freshwater Upper Cretaceous (Campanian) sediments of the Dinosaur Park Formation of Alberta, Canada. Following the description of the Albertan species, numerous isolated cranial and postcranial elements have been collected from the Dinosaur Park Formation and assigned to B.
Mondo Miyazato, Luke E. Nelson, Joshua A. Doyon, Donald B. Brinkman, Alison M. Murray   +4 more
wiley   +1 more source

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

The Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore, Madeline Tourigny, Diana Quinonez, Kevin Barr, Matthew W. Grol, Katherine E. Willmore   +5 more
wiley   +1 more source

Genome-wide analyses of gene expression during mouse endochondral ossification. [PDF]

, 2010
Endochondral ossification is a complex process involving a series of events that are initiated by the establishment of a chondrogenic template and culminate in its replacement through the coordinated activity of osteoblasts, osteoclasts and endothelial ...
Hanga Agoston, Claudine G James, James Claudine G., Stanton Lee-Anne, Underhill T. Michael, Ulici Veronica, Frank Beier, Lee-Anne Stanton, T Michael Underhill, Veronica Ulici, Beier Frank, Agoston Hanga   +11 more
core   +1 more source

Familial multiple exostosis arising from bones of enchondral as well as membranous (in a family affecting seven members)

Indian Journal of Medical and Paediatric Oncology, 2012
Familial multiple exostosis in a family of seven members who are affected found that exostosis was arising both from bones of enchondral as well as membranous ossification, which was sessile as well as pedunculated and was larger in size at the growing ...
Maruti Kambali, H Priyamargavi, Shiek Nazeer, Debojyothi Mukherjee, N S Gudi   +4 more
doaj   +1 more source

Hdac-Mediated Control of Endochondral and Intramembranous Ossification [PDF]

Critical Reviews™ in Eukaryotic Gene Expression, 2011
Histone deacetylases (Hdacs) remove acetyl groups (CH3CO-) from ε-amino groups in lysine residues within histones and other proteins. This posttranslational (de) modification alters protein stability, protein-protein interactions, and chromatin structure.
Elizabeth W, Bradley, Meghan E, McGee-Lawrence, Jennifer J, Westendorf   +2 more
openaire   +2 more sources

Integrating whole‐bone and regional analyses to understand human scapular growth

The Anatomical Record, EarlyView.
Abstract This study investigates ontogenetic changes in human scapular morphology using three‐dimensional geometric morphometrics with whole‐bone and region‐specific analyses. The aim is to evaluate whether the scapula follows a regular developmental pattern and whether its functionally distinct components, the scapular spine (SS) and glenoid fossa ...
Azahara Salazar‐Fernández, José Miguel Carretero, Laura Rodríguez, Rebeca García‐González   +3 more
wiley   +1 more source