Results 51 to 60 of about 18,120 (213)

Epigenetic dynamic during endochondral ossification and articular cartilage development [PDF]

, 2018
International audienceWithin the last decade epigenetics has emerged as fundamental regulator of numerous cellular processes, including those orchestrating embryonic and fetal development.
Karim Boumédiene, Lyess Allas, Catherine Baugé, Allas, Lyess, Boumediene, Karim, Baugé, Catherine   +5 more
core   +1 more source

Chondrogenically differentiated mesenchymal stromal cell pellets stimulate endochondral bone regeneration in critical-sized bone defects [PDF]

European Cells & Materials, 2014
Grafting bone defects or atrophic non-unions with mesenchymal stromal cells (MSCs)-based grafts is not yet successful. MSC-based grafts typically use undifferentiated or osteogenically differentiated MSCs and regenerate bone through intramembranous ...
J van der Stok, MKE Koolen, H Jahr, N Kops, JH Waarsing, H Weinans, OP van der Jagt   +6 more
doaj   +1 more source

Incomplete Endochondral Ossification Of The Otic Capsule, A Variation In Children: Evaluation Of Its Prevalence And Extent In Children With And Without Sensorineural Hearing Loss [PDF]

, 2015
BACKGROUND AND PURPOSE: Endochondral ossification of the otic capsule is a process that continues postnatally; hence, incomplete endochondral ossification is seen as pericochlear hypoattenuation on temporal bone CT scans of children.
Sarac, S., Sanverdi, S. E., Dolgun, A., Ozgen, B.   +3 more
core   +3 more sources

Engineering Small-Scale and Scaffold-Based Bone Organs via Endochondral Ossification Using Adult Progenitor Cells [PDF]

, 2016
Bone development, growth, and repair predominantly occur through the process of endochondral ossification, characterized by remodelling of cartilaginous templates.
Atanas Todorov, Piccinini, Elia, Tonnarelli, Beatrice, Papadimitropoulos, Adam, Beatrice Tonnarelli, Barbero, Andrea, Celeste Scotti, Centola, Matteo, Todorov, Atanas, Andrea Barbero, Scotti, Celeste, Elia Piccinini, Martin, Ivan, Ivan Martin, Adam Papadimitropoulos, Matteo Centola   +15 more
core   +1 more source

Endochondral ossification of hindlimbs in embryonic development of Japanese Quail (Coturnix japonica)

Avian Research
The endochondral ossification of hindlimb is essential to a bird's ability to stand, walk and fly. Most hindlimb is ossified in the embryos before hatching in precocial birds.
Xuan Li, Yuxin Zhang, Hongfeng Zhao
doaj   +1 more source

Spatiotemporal assessment of endochondral ossification. [PDF]

, 2014
Although from different experimental cohorts, the time course of endochondral ossification observed as a gradient of green to red in the right hand case study in (B) can be tied to the spatial gradient of mineralization observed as a gradient from pink ...
Gerald M. Saidel (270446), Melissa L. Knothe Tate (137064), Ulf Knothe (589297), Shannon R. Moore (192565)   +3 more
core   +1 more source

Maternal Gut Microbiome Decelerates Fetal Endochondral Bone Formation by Inducing Inflammatory Reaction

Microorganisms, 2022
To investigate the effect of the maternal gut microbiome on fetal endochondral bone formation, fetuses at embryonic day 18 were obtained from germ-free (GF) and specific-pathogen-free (SPF) pregnant mothers.
Yoko Uchida-Fukuhara, Takako Hattori, Shanqi Fu, Sei Kondo, Miho Kuwahara, Daiki Fukuhara, Md Monirul Islam, Kota Kataoka, Daisuke Ekuni, Satoshi Kubota, Manabu Morita, Mika Iikegame, Hirohiko Okamura   +12 more
doaj   +1 more source

Detection of hypoxia inducible factors and angiogenic growth factors during foetal endochondral and intramembranous ossification [PDF]

, 2010
During skeletogenesis, the development of a new vascular network, i.e. angiogenesis, is triggered by hypoxia through the activation of the hypoxia inducible factors (HIFs) HIF-1a and HIF-2a.
Cornillie, Pieter, P. Cornillie, W. De Spiegelaere, De Spiegelaere, Ward, Burvenich, Christian Paul G., W. Van den Broeck, Van Den Broeck, Wim, Casteleyn, Christophe, C. Burvenich, C. Casteleyn   +9 more
core   +1 more source

Chondrocytes in fracture healing: A review of chondrocyte journey

Chinese Medical Journal
. Previous studies have confirmed that chondrocytes are derived from mesenchymal stem cells (MSCs) and mature into hypertrophic chondrocytes during endochondral ossification.
Tao Zhang, Juan Wang, Siming Jia, Kai Ding, Xiaofeng Du, Hongzhi Lyu, Zhiyong Hou, Renjie Chai, Wei Chen, Jinjiao Li   +9 more
doaj   +1 more source

Plasma exosome miRNA-26b-3p derived from idiopathic short stature impairs longitudinal bone growth via the AKAP2/ERK1/2 axis

Journal of Nanobiotechnology, 2023
Background Currently, the etiology of idiopathic short stature (ISS) is still unclear. The poor understanding of the molecular mechanisms of ISS has largely restricted this strategy towards safe and effective clinical therapies.
Xijuan Liu, Jinghong Yuan, Zhiwen Wu, Junqiu Zhang, Yunfeng Shen, Jingyu Jia   +5 more
doaj   +1 more source