Results 31 to 40 of about 16,681 (209)

Influence of genetic factors on neurophysiological mechanisms of neurodegenerative diseases

Анналы клинической и экспериментальной неврологии, 2018
The review summarizes the main results of studies on the influence of genetic factors on neurophysiological changes in neurodegenerative age-related diseases Alzheimer's (AD), Parkinson's (PD) and Huntington (HD) diseases.
Natalia V. Ponomareva, Vitaliy F. Fokin, Evgeny I. Rogaev, Sergey N. Illarioshkin   +3 more
doaj   +1 more source

Phenomic Selection Is a Low-Cost and High-Throughput Method Based on Indirect Predictions: Proof of Concept on Wheat and Poplar

G3: Genes, Genomes, Genetics, 2018
Genomic selection - the prediction of breeding values using DNA polymorphisms - is a disruptive method that has widely been adopted by animal and plant breeders to increase productivity.
Renaud Rincent, Jean-Paul Charpentier, Patricia Faivre-Rampant, Etienne Paux, Jacques Le Gouis, Catherine Bastien, Vincent Segura   +6 more
doaj   +1 more source

Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains [PDF]

, 2017
BACKGROUND: A range of endophenotypes characterise psychosis, however there has been limited work understanding if and how they are inter-related. METHODS: This multi-centre study includes 8754 participants: 2212 people with a psychotic disorder, 1487 ...
T. Toulopoulou, Daniel, C., Lin, K., B. Crespo-Facorro, Van Os, J., A. M. McIntosh, Rujescu, D., Os, J. V., Kahn, R, M. Picchioni, McIntosh, AM, Picchioni, M., Van Os, J, M. Di Forti, Toulopoulou, Timothea, Ranlund, S, Thygesen, J. H., M.-H. Hall, Crespo-Facorro, B, Blakey, R., Diez-Revuelta, A., Walshe, M, E. Bramon, Á. Díez-Revuelta, J. Powell, null null, Schulze, K, Di Forti, M, Presman, A, Jones, R., E. Zartaloudi, Kahn, R., Van Haren, N., Jablensky, A, S. Calafato, Powell, J, GROUP, W. Cahn, Iyegbe, C., S. Ranlund, Hall, M-H, K. Schulze, Iyegbe, C, Kalaydjieva, L, McDonald, C., L. Kalaydjieva, N. Van Haren, Daniel, C, Cahn, W, Crespo-Facorro, B., Kalaydjieva, L., Hall, M. -H., R. Jones, Zartaloudi, E., Bramon, E, Murray, RM, Jones, R, Toulopoulou, T, Schulze, K., Murray, R M, K. Lin, Presman, A., C. Daniel, D. Rujescu, Picchioni, M, Murray, R. M., McDonald, C, Forti, M. D., Thygesen, JH, A. Presman, Jablensky, A., Haren, N. V., R. Blakey, R. Kahn, M. Shaikh, Blakey, R, Rujescu, D, Shaikh, M., R. M. Murray, Colizzi, M, Bramon, E., M. Colizzi, C. McDonald, Shaikh, M, Kravariti, E, C. Iyegbe, Calafato, S., Kravariti, E., Di Forti, M., Colizzi, M., Hall, M.-H., Walshe, M., Zartaloudi, E, Ranlund, S., Díez-Revuelta, Á, J. H. Thygesen, Thygesen, J H, Calafato, S, E. Kravariti, McIntosh, A. M., A. Jablensky, McIntosh, A M, Cahn, W., Toulopoulou, T., Lin, K, J. Van Os, Powell, J., Van Haren, N, M. Walshe   +108 more
core   +3 more sources

Application of eye trackers for understanding mental disorders: Cases for schizophrenia and autism spectrum disorder

Neuropsychopharmacology Reports, 2019
Studies of eye movement have become an essential tool of basic neuroscience research. Measures of eye movement have been applied to higher brain functions such as cognition, social behavior, and higher‐level decision‐making.
Emiko Shishido, Shiori Ogawa, Seiko Miyata, Maeri Yamamoto, Toshiya Inada, Norio Ozaki   +5 more
doaj   +1 more source

SNAP-25 Polymorphisms in Autism Spectrum Disorder: A Pilot Study towards a Possible Endophenotype

Pediatric Reports, 2023
While there is substantial agreement on the diagnostic criteria for autism spectrum disorder, it is also acknowledged that it has a broad range of clinical presentations.
Martina Maria Mensi, Franca Rosa Guerini, Michele Marchesi, Matteo Chiappedi, Elisabetta Bolognesi, Renato Borgatti   +5 more
doaj   +1 more source

Endophenotypes in a Dynamically Connected Brain [PDF]

Behavior Genetics, 2010
We examined the longitudinal genetic architecture of three parameters of functional brain connectivity. One parameter described overall connectivity (synchronization likelihood, SL). The two others were derived from graph theory and described local (clustering coefficient, CC) and global (average path length, L) aspects of connectivity.
Smit, D. J.A., Boersma, M., Van Beijsterveldt, C. E.M., Posthuma, D., Boomsma, D. I., Stam, C. J., De Geus, E. J.C.   +6 more
openaire   +3 more sources

Social cognition in siblings of patients with bipolar disorders

Industrial Psychiatry Journal, 2021
Background: Identifying people at risk of developing bipolar disorder (BD) using endophenotypes is of recent interest. Few studies on social cognition in first-degree relatives of patients with BD have shown inconsistent findings.
Swati Choudhary, B N Subodh, Sandeep Grover   +2 more
doaj   +1 more source

Association Between Toe Walking and Repetitive Behaviors in Children with Autism Spectrum Disorder: A Cross-Sectional Phenotypic Analysis

Medicina
Background and Objectives: Toe walking (TW) is frequently observed in children with Autism Spectrum Disorder (ASD), yet its clinical significance remains incompletely understood.
Martina Gnazzo, Giuditta Bargiacchi, Beatrice Gallai, Giulia Spoto, Gabriella Di Rosa, Valentina Baldini, Lucia Parisi, Agata Maltese, Michele Roccella, Eva Germanò, Maria Esposito, Marco Carotenuto   +11 more
doaj   +1 more source

Smaller left anterior cingulate cortex in non-bipolar relatives of patients with bipolar disorder

Brazilian Journal of Psychiatry, 2018
Objective: Bipolar disorder (BD) is highly heritable. The present study aimed at identifying brain morphometric features that could represent markers of BD vulnerability in non-bipolar relatives of bipolar patients.
Marsal Sanches, Edilberto Amorim, Benson Mwangi, Giovana B. Zunta-Soares, Jair C. Soares   +4 more
doaj   +1 more source

A Videogame as a Tool for Clinical Screening of Possible Vulnerability to Impulsivity and Attention Disturbances in Children

Children, 2022
An attention disturbance is a problem that affects many school-aged children. The assessment in children is usually report-based, and as a result, controversy surrounds the diagnosis.
Almudena Serrano-Barroso, Juan Pedro Vargas, Estrella Diaz, Isabel M. Gómez-González, Gabriel Ruiz, Juan Carlos López   +5 more
doaj   +1 more source