Results 61 to 70 of about 16,681 (209)
Endophenotypes in psychopathology research : Where do we stand?
Endophenotypes for psychopathology have beenn conceived as latent, unobserved, but measureable manifestations of phenomena that causally connect genetic liability to clinical disorder.
Rockstroh, Brigitte, Miller, Gregory A.
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The dog is a valuable model for studying social behavior and neuropsychiatric disease. We generated an ATAC‐seq atlas of 7 brain regions and pituitary from 4 beagles, identifying 251,492 CREs. Integrating dog‐wolf divergence revealed tissue‐specific CREs overlapping divergent loci, including neuronal and neuroendocrine genes.
Biao Deng +15 more
wiley +1 more source
Although schizophrenia has a high heritability, the genetic effects conferring diathesis to schizophrenia are thought to be complex and underlain by multifactorial polygenic inheritance.
WatersMetenier, SL +3 more
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Structural endophenotypes of mTLE+HS
In this project, we seek to identify possible structural endophenotypes in unaffected relatives of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE+HS)
Siti Nurbaya Yaakub
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Endophenotypes of psychosis [PDF]
There is growing appreciation that the major psychiatric disorders may be composed of sub-syndromes that can be characterized by specific pathophysiological markers. For example, schizophrenia can be deconstructed into several separable sub-syndromes i.e., psychosis, negative symptoms, and mood instability.
openaire +2 more sources
Hunting genes, hunting endophenotypes [PDF]
AbstractIdentifying specific genetic contributions to psychopathology has proved to be much more difficult than anticipated. In pursuit of this goal, Iacono and colleagues provide a remarkable set of studies that are important for the methods showcased as well as the findings reported.
Gregory A, Miller +2 more
openaire +2 more sources
AIMS/HYPOTHESIS: The cluster of obesity, insulin resistance, dyslipidaemia and hypertension, called the metabolic syndrome, has been suggested as a risk factor for cardiovascular disease and type 2 diabetes.
Visscher, P M +11 more
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A literature review of ophthalmic endophenotypes for schizophrenia [PDF]
The article presents a literature review of the concept of endophenotypes in schizophrenia. The main ophthalmic endophenotypes are considered as diagnostic criteria for schizophreniaВ статье представлен литературный обзор концепции эндофенотипов при ...
Bogdanov, S. I. +3 more
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The Genetic Architecture of Alzheimer's Disease Endophenotypes
Indiana University-Purdue University Indianapolis (IUPUI)Alzheimer’s Disease (AD) is one of the most common forms of dementia and is known to have a strong genetic component, but known genetic loci do not fully account for the observed genetic ...
Jacobson, Tanner Young
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ABSTRACT Cowpea (Vigna unguiculata L. Walp) is a multi‐use crop highly valued as a food crop, high‐protein fodder, and sustainable cover crop. Yet, it remains underused, and yields in most growing regions are below the crop's potential due to multiple biotic and abiotic stresses.
Habib Akinmade +3 more
wiley +1 more source

