Results 71 to 80 of about 16,681 (209)
Expanding the phenotype and endophenotype of AD [PDF]
Journal of the European Academy of Dermatology and Venereology, 2020 Linked articles: S. Wang et al. J Eur Acad Dermatol Venereol 2020; 34: 2346–2352.
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Genomic and phenomic prediction models improve selection accuracy for complex traits in alfalfa
The Plant Phenome Journal, Volume 9, Issue 1, December 2026.Abstract Predictive breeding has been proposed as an effective approach to accelerate genetic gain for complex traits. Genomic prediction (GP) models have been developed in alfalfa (Medicago sativa L.) for key traits in the last decade. More recently, phenomic prediction (PP) models have been proposed as a low‐cost, high‐throughput alternative to GP in
Pablo Sipowicz +8 more
wiley +1 more source
Transcriptome-Wide Association Supplements Genome-Wide Association in Zea mays
G3: Genes, Genomes, Genetics, 2019 Modern improvement of complex traits in agricultural species relies on successful associations of heritable molecular variation with observable phenotypes. Historically, this pursuit has primarily been based on easily measurable genetic markers.
Karl A. G. Kremling +4 more
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Frontiers in Behavioral Neuroscience, 2020 Distinct manifestations of sexual behavior are conceived as separate phenotypes. Each sexual phenotype is assumed to be associated with a characteristic brain.
Itztli Trejo-Sánchez +5 more
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Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches
Analysis &Sensing, Volume 6, Issue 6, November 2026.The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi +2 more
wiley +1 more source
Addiction Biology, Volume 31, Issue 11, November 2026.Astrocytic GAT3 regulates ambient GABA levels in the globus pallidus externus (GPe). Reduced GAT3 function enhances extrasynaptic GABAergic signalling and disrupts subthalamic nucleus (STN) regulation and cortical signal fidelity.ABSTRACTAlcohol use disorder (AUD) is characterized by a shift from controlled, goal‐directed drinking to compulsive ...
Hannah Aranda +3 more
wiley +1 more source
Genetics of Cognitive Endophenotypes in Schizophrenia : a Family-Based Study [PDF]
, 2009 Schizophrenia is a highly heritable, though complex disease; multiple genes and environmental factors influence its development. Most of these genes have small effects on schizophrenia.
Aukes, M.F. +4 more
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Neurocognitive Angle: The Search for Endophenotypes
, 2012 This chapter contains sections titled: Introduction Heritability of OCD The concept of an endophenotype Applying the endophenotype construct to OCD Domains of interest in hierarchical modelling of OCD Searching for endophenotypes of OCD
Lara Menzies +3 more
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Advanced Science, Volume 13, Issue 58, 19 October 2026.Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li +10 more
wiley +1 more source
Endophenotypes in the personality disorders
Dialogues in Clinical Neuroscience, 2005 The identification of endophenotypes in the personality disorders may provide a basis for the identification of underlying genotypes that influence the traits and dimensions of the personality disorders, as well as susceptibility to major psychiatric illnesses.
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