Results 101 to 110 of about 127,657 (311)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Advanced GeneticsThe VISTA enhancer database is a valuable resource for evaluating predicted enhancers in humans and mice. In addition to thousands of validated positive regions (VPRs) in the human and mouse genomes, the database also contains similar numbers of ...
Pengyu Ni, Siwen Wu, Zhengchang Su
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The summary of the overlap between the predicted enhancers and the FANTOM5 enhancers.
, 2016 The summary of the overlap between the predicted enhancers and the FANTOM5 enhancers.
Yang Dai (36730) +2 more
core +1 more source
Enhancers of eight Gossypium species.
, 2021 Enhancers of eight Gossypium ...
Jianying Li (9426689)
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Journal of Bioinformatics and GenomicsЦель проделанной нами работы состояла в выявлении регуляторного потенциала микросателлитной некодирующей ДНК в отношении экспрессии генов. SSRs (Simple Sequence Repeats), в настоящее время используются для картирования и поиска генов, определения родства,
Пензин А.А., Тимкин П.Д.
doaj +1 more source
eLife, 2016 Enhancers constitute one of the major components of regulatory machinery of metazoans. Although several genome-wide studies have focused on finding and locating enhancers in the genomes, the fundamental principles governing their internal architecture ...
Rupinder Sayal +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2013 (A) The motifs with bootstrap confidence over 65%. The confidence levels are shown as bars and are colour-coded with darker color for larger confidence.
Manfred Frasch (104582) +5 more
core +1 more source