Results 101 to 110 of about 24,147 (238)

Role of carbon dioxide and ion transport in the formation of sub-embryonic fluid by the blastoderm of the Japanese quail [PDF]

, 2002
1. The explanted blastoderm of the Japanese quail was used to explore the role of ions and carbon dioxide in determining the rate of sub-embryonic fluid (SEF) production between 54 and 72 h of incubation. 2.
AR A., BABIKER E.M., BECKER WA., BENOS DJ., BORON W.F., BRAKE J., COTTERILI O.J., DODGSON S.J., DODGSON S.J., EHRENFELD J., FRITSCHE C., HANSSON H.P.J., MAHEN T.H., MAREN T.H., MUELLER W.J., NEW D.A.T., NEW D.A.T., REUSS L., ROMANOFF A.L., ROMANOFF A.L., SIMKISS K., SOKAL R.R., STERN C.D., STERN C.D., TAYLOR L.W., TAYLOR L.W., WALSH T.J., ZEUTHEN T.   +27 more
core   +1 more source

H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A‐Driven EP300 Expression

Advanced Science, Volume 12, Issue 41, November 6, 2025.
An et al. reveal H3K27ac elevation is essential for establishing and maintaining human naive pluripotency; its inhibition disrupts this state while enhancement promotes it. METTL3‐mediated m6A modification indirectly controls H3K27ac by suppressing EP300 expression. Reduced EP300 lowers H3K27ac, impeding naive pluripotency.
Chenrui An, Ke Zhong, Xiangjin Kang, Yingying Zhang, Yudan Shang, Hao Liu, Yushan Ji, Jinbei Zeng, Jiajin Lin, Long Jin, Zelong Lin, Yang Yu, Xuetao Shi, Yong Fan   +13 more
wiley   +1 more source

Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells

BioEssays, Volume 47, Issue 11, November 2025.
Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley   +1 more source

Remarks on taxonomy of some species of Elytrigia S.L. (Triticeae) in the light of embryo morphology

Acta Societatis Botanicorum Poloniae, 2014
Embryos of 21 accessions of the genus Elytrigia s.l. were studied. Characters of scutellum, coleoptile, coleorhiza and epiblast were taken into consideration. Correlation of characters proves an independence of epiblast organogenesis.
Romuald Kosina
doaj   +1 more source

Mutations in GFAP Alter Early Lineage Commitment of Organoids

Glia, Volume 73, Issue 11, Page 2167-2188, November 2025.
Main Points Mutations in GFAP alter lineage commitment of organoids. The severity of this commitment defect is dependent on method of embryoid body formation. GFAP is expressed in iPSCs and during early stages of organoid development. . ABSTRACT Glial fibrillary acidic protein (GFAP) is a type‐3 intermediate filament protein mainly expressed in ...
Werner Dykstra, Zuzana Matusova, Rachel A. Battaglia, Pavel Abaffy, Nuria Goya‐Iglesias, Dolores Pérez‐Sala, Henrik Ahlenius, Mikael Kubista, R. Jeroen Pasterkamp, Li Li, Jianfei Chao, Yanhong Shi, Lukas Valihrach, Milos Pekny, Elly M. Hol   +14 more
wiley   +1 more source

Mettl14 is required for mouse post-implantation development by facilitating epiblast maturation

bioRxiv, 2018
N6-methyladenosine (m6A) is the most prevalent and reversible internal modification of mammalian messenger and noncoding RNAs mediated by specific m6A writer, reader, and eraser proteins.
Tie‐Gang Meng, Xukun Lu, Lei Guo, Guanmei Hou, Xue-Shan Ma, Qian-Nan Li, Lin Huang, Li-Hua Fan, Zheng-Hui Zhao, Xiang-Hong Ou, Yingchun Ouyang, H. Schatten, Lei Li, Zhenbo Wang, Qing-Yuan Sun   +14 more
semanticscholar   +1 more source

Challenges and possible clinical applications of human embryonic stem cell research [PDF]

, 2012
Human embryonic stem cells (hESC) are harvested from the inner cell mass of the pre-implantation embryo and possess several unique characteristics. First, they are self-renewing, meaning they can grow indefinitely in an appropriate culture environment ...
De Sutter, Petra, Heindryckx, Björn, O'Leary, Thomas, Van der Jeught, Margot   +3 more
core   +1 more source

Human Endogenous Retroviruses and Diseases

MedComm, Volume 6, Issue 11, November 2025.
Human endogenous retroviruses (HERVs), remnants of ancient retroviral integrations into the human genome, are modulated by viral infections, genetic inheritance, and triggers including environmental factors, epigenetic dysregulation, oncogene activation, and aging.
Can Chen, Yanru Cui, Shixiang Wang, Yuze Yang, Zunpeng Liu, Suhan Jin, Fangqian Shen, Udo Gaipl, Hu Ma, Jian‐Guo Zhou   +9 more
wiley   +1 more source

Dynamics of Wnt activity on the acquisition of ectoderm potency in epiblast stem cells

Development, 2019
During embryogenesis, the stringent regulation of Wnt activity is crucial for the morphogenesis of the head and brain. The loss of function of the Wnt inhibitor Dkk1 results in elevated Wnt activity, loss of ectoderm lineage attributes from the anterior ...
P. Osteil, Joshua B. Studdert, Hwee Ngee Goh, Emilie E. Wilkie, Xiaochen Fan, P. Khoo, Guangdun Peng, Nazmus Salehin, Hilary Knowles, J. Han, N. Jing, Nicolas Fossat, P. Tam   +12 more
semanticscholar   +1 more source

Tracing blastomere fate choices of early embryos in single cell culture [PDF]

, 2010
Blastomeres of early vertebrate embryos undergo numerous fate choices for division, motility, pluripotency maintenance and restriction culminating in various cell lineages.
Chang Ming Li, Haobin Zhao, Jianxin Song, Meisheng Yi, Mingyou Li, Ni Hong, Rong Liu, Ruowen Ge, Yan Yan, Yongming Yuan, Yunhan Hong, Zhendong Li   +11 more
core   +1 more source