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Pulmonary Pathogen-Induced Epigenetic Modifications
Epigenomes, 2023 Epigenetics generally involves genetic control by factors other than our own DNA sequence. Recent research has focused on delineating the mechanisms of two major epigenetic phenomena: DNA methylation and histone modification. As epigenetics involves many
Dylan Wrede +3 more
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Dysregulated epigenetic modifications in psoriasis [PDF]
Experimental Dermatology, 2021 AbstractThe observed incidence of psoriasis has been gradually increasing over time (J Am Acad Dermatol, 03, 2009, 394), but the underlying pathogenic factors have remained unclear. Recent studies suggest the importance of epigenetic modification in the pathogenesis of psoriasis.
Chang Zeng +2 more
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Epigenetic Modification: A Key Tool for Secondary Metabolite Production in Microorganisms
Frontiers in Microbiology, 2022 Microorganisms are stupendous source of secondary metabolites, having significant pharmaceutical and industrial importance. Genome mining has led to the detection of several cryptic metabolic pathways in the natural producer of secondary metabolites (SMs)
Sudha Bind +3 more
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Frontiers in Immunology, 2022 T2DM, as a typical metabolic inflammatory disease, is under the joint regulation of environmental factors and genetics, combining with a variety of epigenetic changes.
Qi-You Ding +5 more
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Research progress of immune response regulated by epigenetic modification in pneumonia
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Pneumonia is one of the most common infectious diseases, and although considerable progress has been made in the diagnosis and treatment of pneumonia, it is still associated with high mortality, prolonged hospitalization, and significant medical ...
WANG Qing, HAN Xiao, ZHANG Xiaobo
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Epigenetic Modification of PD-1/PD-L1-Mediated Cancer Immunotherapy against Melanoma
International Journal of Molecular Sciences, 2022 Malignant melanoma is one of the representative skin cancers with unfavorable clinical behavior. Immunotherapy is currently used for the treatment, and it dramatically improves clinical outcomes in patients with advanced malignant melanoma.
Hikaru Nanamori, Y. Sawada
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Epigenetics: Novel crucial approach for osteogenesis of mesenchymal stem cells
Journal of Tissue Engineering, 2023 Bone has a robust regenerative potential, but its capacity to repair critical-sized bone defects is limited. In recent years, stem cells have attracted significant interest for their potential in tissue engineering. Applying mesenchymal stem cells (MSCs)
Zhaohua Wang +8 more
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Epigenetic Regulation in Pathology of Atherosclerosis: A Novel Perspective
Frontiers in Genetics, 2021 Atherosclerosis, characterized by atherosclerotic plaques, is a complex pathological process that involves different cell types and can be seen as a chronic inflammatory disease.
Haishuang Tang +4 more
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Microbiology Research, 2021 Epigenetic studies on secondary metabolites (SMs) mainly relied so far on non-selective epigenetic factors deletion or feeding epigenetic inhibitors in Aspergillus niger.
Xuejie Li +4 more
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Cadmium disturbs epigenetic modification and induces DNA damage in mouse preimplantation embryos.
Ecotoxicology and Environmental Safety, 2021 Cadmium is an environmental pollutant that has extensive deleterious effects on the reproductive system. However, the mechanisms underlying the effects of cadmium on preimplantation embryos are unclear.
Jiaqiao Zhu +9 more
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