Results 31 to 40 of about 2,264,000 (323)
Fruit development and epigenetic modifications [PDF]
New Phytologist, 2020 SummaryFruit development is a complex process that is regulated not only by plant hormones and transcription factors, but also requires epigenetic modifications. Epigenetic modifications include DNA methylation, histone post‐translational modifications, chromatin remodeling and noncoding RNAs.
Tang, Dengguo +2 more
openaire +3 more sources
Epigenetic modifications in cancer [PDF]
Clinical Genetics, 2011 Kanwal R, Gupta S. Epigenetic modifications in cancer.Cancer initiation and progression is controlled by both genetic and epigenetic events. The complexity of carcinogenesis cannot be accounted for by genetic alterations alone but also involves epigenetic changes. Epigenetics refers to the study of mechanisms that alter gene expression without altering
R, Kanwal, S, Gupta
openaire +2 more sources
Change of epigenetic modification and human reproduction
Asian Pacific Journal of Reproduction, 2016 In recent years, it has become consumedly clear that changing of epigenetic modification is essential during both early and late oogenesis and spermatogenesis. Also epigenetic modifications are involved in some cases such as embryo development and growth,
Jafar Nouri Nojadeh, Hossein Daghghagh
doaj +1 more source
Epigenetic Modifications during Angiosperm Gametogenesis [PDF]
Frontiers in Plant Science, 2012 Angiosperms do not contain a distinct germline, but rather develop gametes from gametophyte initials that undergo cell division. These gametes contain cells that give rise to an endosperm and the embryo. DNA methylation is decreased in the vegetative nucleus (VN) and central cell nuclei (CCN) resulting in expression of transposable elements (TEs).
Migicovsky, Zoë, Kovalchuk, Igor
openaire +3 more sources
Epigenetic modifications as therapeutic targets [PDF]
Nature Biotechnology, 2010 Epigenetic modifications work in concert with genetic mechanisms to regulate transcriptional activity in normal tissues and are often dysregulated in disease. Although they are somatically heritable, modifications of DNA and histones are also reversible, making them good targets for therapeutic intervention.
Kelly, Theresa K +2 more
openaire +2 more sources
Editorial: Epigenetic Modifications in Mesothelioma [PDF]
Frontiers in Oncology, 2021 We are pleased to announce the publication of this Research Topic focusing on epigenetic modifications in mesothelioma. Epigenetic modification has been investigated for the past two decades. It is a key process of cellular development as well as carcinogenesis.
Yuen Yee Cheng +2 more
openaire +3 more sources
Epigenetic modifications in prostate cancer [PDF]
International Journal of Urology, 2020 AbstractProstate cancer is a major cause of cancer‐related deaths among men worldwide. In addition to genomic alterations, epigenetic alterations accumulated in prostate cancer have been elucidated. While aberrant deoxyribonucleic acid hypermethylation in promoter CpG islands inactivates crucial genes associated with deoxyribonucleic acid repair, cell ...
Masahiro, Sugiura +6 more
openaire +2 more sources
Epigenetic modification mechanisms involved in keloid: current status and prospect
Clinical Epigenetics, 2020 Keloid, a common dermal fibroproliferative disorder, is benign skin tumors characterized by the aggressive fibroblasts proliferation and excessive accumulation of extracellular matrix.
Wenchang Lv +8 more
semanticscholar +1 more source
Different Behavioral Experiences Produce Distinctive Parallel Changes in, and Correlate With, Frontal Cortex and Hippocampal Global Post-translational Histone Levels. [PDF]
, 2018 While it is clear that behavioral experience modulates epigenetic profiles, it is less evident how the nature of that experience influences outcomes and whether epigenetic/genetic biomarkers could be extracted to classify different types of behavioral ...
Cory-Slechta, Deborah A. +3 more
core +2 more sources
Epigenetic modifications in cardiovascular disease [PDF]
Basic Research in Cardiology, 2012 Epigenetics represents a phenomenon of altered heritable phenotypic expression of genetic information occurring without changes in DNA sequence. Epigenetic modifications control embryonic development, differentiation and stem cell (re)programming. These modifications can be affected by exogenous stimuli (e.g., diabetic milieu, smoking) and oftentimes ...
Lorenzen, Johan M. +2 more
openaire +2 more sources