Manipulation of Epigenome: Opportunities and Pitfalls in Fighting Autoimmune Diseases [PDF]
International Journal of Biomedicine, 2022 Many recent studies have focused on the manipulation of the epigenome to understand the mechanistic programming in health and some disease phenotypes.
Hassan Higazi +6 more
doaj +1 more source
Plants regenerated from tissue culture contain stable epigenome changes in rice. [PDF]
, 2013 Most transgenic crops are produced through tissue culture. The impact of utilizing such methods on the plant epigenome is poorly understood. Here we generated whole-genome, single-nucleotide resolution maps of DNA methylation in several regenerated rice ...
Bellizzi, Maria +8 more
core +2 more sources
Biomolecular Concepts, 2022 One pillar of the predictive, preventive, and personalized medicine framework strategies is the female health. The evaluation of women’s lifestyle and dietary habits in context with genetic and modifiable risk factors may reflect the prevention of ...
Holubekova Veronika +10 more
doaj +1 more source
The Unicellular State as a Point Source in a Quantum Biological System. [PDF]
, 2016 A point source is the central and most important point or place for any group of cohering phenomena. Evolutionary development presumes that biological processes are sequentially linked, but neither directed from, nor centralized within, any specific ...
Miller, William B, Torday, John S
core +3 more sources
Global Reprogramming of Apoptosis-Related Genes during Brain Development
Cells, 2021 To enable long-term survival, mammalian adult neurons exhibit unique apoptosis competence. Questions remain as to whether and how neurons globally reprogram the expression of apoptotic genes during development.
Wei Jiang, Liang Chen, Sika Zheng
doaj +1 more source
Residential Proximity to Major Roadways at Birth, DNA Methylation at Birth and Midchildhood, and Childhood Cognitive Test Scores: Project Viva(Massachusetts, USA). [PDF]
, 2018 BackgroundEpigenetic variability is hypothesized as a regulatory pathway through which prenatal exposures may influence child development and health.ObjectiveWe sought to examine the associations of residential proximity to roadways at birth and ...
Agha, Golareh +20 more
core +1 more source
Women's perception, attitudes, and intended behavior towards predictive epigenetic risk testing for female cancers in 5 European countries: A cross-sectional online survey [PDF]
, 2019 BACKGROUND: Epigenetic markers might be used for risk-stratifying cancer screening and prevention programs in the future. Although the clinical utility of consequent epigenetic tests for risk stratification is yet to be proven, successful adoption into ...
Pashayan, N. +3 more
core +1 more source
Detection of suspicious interactions of spiking covariates in methylation data [PDF]
, 2020 BACKGROUND: In methylation analyses like epigenome-wide association studies, a high amount of biomarkers is tested for an association between the measured continuous outcome and different covariates.
Kruppa, Jochen +3 more
core +1 more source
In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children. [PDF]
, 2019 BackgroundMaternal smoking during pregnancy is a risk factor for chronic disease later in life and has been associated with variability of DNA methylation at specific cytosine-phosphate-guanine (CpG) loci.
Barker +47 more
core +1 more source
Transcriptional repression shapes the identity and function of tissue macrophages
FEBS Open Bio, 2021 The changing extra‐ and intracellular microenvironment calls for rapid cell fate decisions that are precisely and primarily regulated at the transcriptional level.
Krisztian Bene +2 more
doaj +1 more source