Results 11 to 20 of about 71,499 (299)
Expression cloning of the epithelial sodium channel [PDF]
Kidney International, 1995 Complex organisms take sodium from the external environment to achieve and maintain extracellular volume and blood pressure. Many sodium transporter systems have evolved, and among them the epithelial sodium channel plays a fundamental role in ...
Schild, L. +7 more
core +3 more sources
The epithelial sodium channel and the processes of wound healing [PDF]
BioMed Research International, 2019 The epithelial sodium channel (ENaC) mediates passive sodium transport across the apical membranes of sodium absorbing epithelia, like the distal nephron, the intestine, and the lung airways.
Chifflet, Silvia +1 more
core +7 more sources
Epithelial sodium channel: a ligand-gated channel? [PDF]
Nephron Physiology, 2004 The epithelial sodium channel (ENaC) is a key component of the transepithelial Na+ transport. In epithelia, it is responsible for the maintenance of Na+ balance (which in turn controls extracellular fluid volume and arterial blood pressure) and the ...
Chraibi, A., Horisberger, J. D.
core +4 more sources
Epithelial Sodium and Chloride Channels and Asthma
Chinese Medical Journal, 2015 Objective: To focus on the asthmatic pathogenesis and clinical manifestations related to epithelial sodium channel (ENaC)/chlorine ion channel. Data Sources: The data analyzed in this review were the English articles from 1980 to 2015 from journal ...
Wen Wang, Hong-Long Ji
doaj +3 more sources
Physiological regulation of epithelial sodium channel by proteolysis [PDF]
Current Opinion in Nephrology & Hypertension, 2011 PURPOSE OF REVIEW: Activation of epithelial sodium channel (ENaC) by proteolysis appears to be relevant for day-to-day physiological regulation of channel activity in kidney and other epithelial tissues.
Per Svenningsen +11 more
core +3 more sources
The Epithelial Sodium Channel-An Underestimated Drug Target. [PDF]
Int J Mol Sci, 2023 Epithelial sodium channels (ENaC) are part of a complex network of interacting biochemical pathways and as such are involved in several disease states. Dependent on site and type of mutation, gain- or loss-of-function generated symptoms occur which span from asymptomatic to life-threatening disorders such as Liddle syndrome, cystic fibrosis or ...
Lemmens-Gruber R, Tzotzos S.
europepmc +4 more sources
Functional Domains of the Epithelial Sodium Channel [PDF]
Journal of the American Society of Nephrology, 2005 The epithelial sodium channel (ENaC) plays an important role in ion transport of many organ systems. In kidney, colon, and sweat gland, ENaC-mediated transepithelial sodium transport helps to adjust sodium excretion in the urine, feces, and sweat to fulfill homeostatic requirements.
Loffing J, Schild L
openaire +4 more sources
Subunit Stoichiometry of the Epithelial Sodium Channel [PDF]
Journal of Biological Chemistry, 1998 The epithelial Na+ Channel (ENaC) mediates Na+ reabsorption in a variety of epithelial tissues. ENaC is composed of three homologous subunits, termed alpha, beta, and gamma. All three subunits participate in channel formation as the absence of any one subunit results in a significant reduction or complete abrogation of Na+ current expression in Xenopus
F, Kosari +5 more
openaire +2 more sources
Turkish Journal of Nephrology, 2020 The epithelial sodium channel (ENaC) is expressed in the aldosterone-sensitive distal nephron, and it determines the final urinary sodium concentration.
Ferruh Artunç
doaj +1 more source
Lipopolysaccharide modifies amiloride-sensitive Na+ transport processes across human airway cells: role of mitogen-activated protein kinases ERK 1/2 and 5 [PDF]
, 2009 Bacterial lipopolysaccharides (LPS) are potent inducers of proinflammatory signaling pathways via the activation of nuclear factor-kappa B (NF-KB) and mitogenactivated protein kinase (MAPK), causing changes in the processes that control lung fluid ...
A. M. Woollhead +17 more
core +1 more source