Results 41 to 50 of about 598,048 (347)

Identification of the Binding Epitope of an Anti-Mouse CCR6 Monoclonal Antibody (C₆Mab-13) Using 1× Alanine Scanning

Antibodies, 2023
CC chemokine receptor 6 (CCR6) is one of the members of the G-protein-coupled receptor (GPCR) family that is upregulated in many immune-related cells, such as B lymphocytes, effector and memory T cells, regulatory T cells, and immature dendritic cells ...
Tomohiro Tanaka, Mayuki Tawara, Hiroyuki Suzuki, Mika K. Kaneko, Yukinari Kato   +4 more
doaj   +1 more source

Current challenges for unseen-epitope TCR interaction prediction and a new perspective derived from image classification

Briefings Bioinform., 2020
The prediction of epitope recognition by T-cell receptors (TCRs) has seen many advancements in recent years, with several methods now available that can predict recognition for a specific set of epitopes.
Pieter Moris, Joey De Pauw, A. Postovskaya, Sofie Gielis, Nicolas De Neuter, Wout Bittremieux, B. Ogunjimi, K. Laukens, P. Meysman   +8 more
semanticscholar   +1 more source

Celiac Immunogenic Potential of α-Gliadin Epitope Variants from Triticum and Aegilops Species [PDF]

, 2019
The high global demand of wheat and its subsequent consumption arise from the physicochemical properties of bread dough and its contribution to the protein intake in the human diet.
Barro Losada, Francisco, Comino Montilla, Isabel María, López Casado, Miguel Ángel, Moreno Amador, María de Lourdes, Ozuna Serafini, Carmen Victoria, Ruiz Carnicer, Ángela, Segura Montero, Verónica, Sousa Martín, Carolina, Torres López, María Isabel   +8 more
core   +1 more source

Epitope mapping for the anti-rabbit cholesteryl ester transfer protein monoclonal antibody that selectively inhibits triglyceride transfer

Journal of Lipid Research, 1999
Among the monoclonal antibodies (Mab) against rabbit plasma cholesteryl ester transfer protein (CETP), Mab 14-8F cross-reacted with human CETP and selectively inhibited triglyceride transfer but not cholesteryl ester transfer (Ko, K. W. S., T.
Kazunori Saito, Ki-ichiro Kobori, Hideyuki Hashimoto, Sachiko Ito, Mitsuhisa Manabe, Shinji Yokoyama   +5 more
doaj   +1 more source

Evaluation of Spike Protein Epitopes by Assessing the Dynamics of Humoral Immune Responses in Moderate COVID-19

Frontiers in Immunology, 2022
The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The spike protein (S) of SARS-CoV-2 is a major target for diagnosis and vaccine development because of ...
Lingyun Chen, Lingyun Chen, Pengfei Pang, Huan Qi, Keqiang Yan, Keqiang Yan, Yan Ren, Mingliang Ma, Ruyin Cao, Hua Li, Chuansheng Hu, Yang Li, Jun Xia, Jun Xia, Danyun Lai, Yuliang Dong, Hewei Jiang, Hainan Zhang, Hong Shan, Shengce Tao, Siqi Liu, Siqi Liu   +21 more
doaj   +1 more source

Fundamentals and Methods for T- and B-Cell Epitope Prediction

Journal of Immunological Research, 2017
Adaptive immunity is mediated by T- and B-cells, which are immune cells capable of developing pathogen-specific memory that confers immunological protection.
J. L. Sánchez-Trincado, Marta Gomez-Perosanz, P. Reche   +2 more
semanticscholar   +1 more source

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools

Frontiers in Immunology, 2020
Computational vaccinology includes epitope mapping, antigen selection, and immunogen design using computational tools. Tools that facilitate the in silico prediction of immune response to biothreats, emerging infectious diseases, and cancers can ...
Anne Searls De Groot, L. Moise, Frances E Terry, A. Gutiérrez, P. Hindocha, Guilhem Richard, D. Hoft, T. Ross, A. Noe, Yoshimasa Takahashi, V. Kotraiah, S. Silk, C. Nielsen, A. Minassian, R. Ashfield, M. Ardito, S. Draper, W. Martin   +17 more
semanticscholar   +1 more source

Immunoinformatic analysis of glycoprotein from bovine ephemeral fever virus

Biomedical and Biotechnology Research Journal, 2018
Background: Bovine ephemeral fever virus (BEFV) is an arthropod-borne virus that is highly infective for cattle and water buffalo. The infection has important economic losses and is common in tropical and subtropical regions.
Mehran Bakhshesh, Mohammad Mehdi Ranjbar, Shokoofeh Almasi   +2 more
doaj   +1 more source

Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites [PDF]

, 2016
Autoantibodies to insulin are a harbinger of autoimmunity in type 1 diabetes in humans and in non-obese diabetic mice. To understand the genesis of these autoantibodies, we investigated the interactions of insulin-specific T and B lymphocytes using T ...
Acevedo-Suárez, Achenbach, Adelstein, Akashi, Batista, Bodansky, Cooke, Crotty, Dean, Emil R. Unanue, Ferris, Gagnerault, Garside, Gitlin, Glazier, Goodnow, Greeley, Gretz, Harbers, Henry, Henry, Henry-Bonami, Hoppu, Hu, Hulbert, Höglund, James W. Thomas, Kendall, Kendall, Kenefeck, Levisetti, Linterman, Mariño, Mohan, Mohan, Mohan, Nakayama, Noorchashm, Okada, Pape, Rasio, Reinhardt, Rojas, Roozendaal, Serreze, Silva, Takahashi, Ueno, Unanue, Victora, Victora, Vinuesa, Vomund, Williams, Xiaoxiao Wan, Yang, Zhang, Zhang, Zikherman, Zotos   +59 more
core   +2 more sources

IEDB-AR: immune epitope database—analysis resource in 2019

Nucleic Acids Res., 2019
The Immune Epitope Database Analysis Resource (IEDB-AR, http://tools.iedb.org/) is a companion website to the IEDB that provides computational tools focused on the prediction and analysis of B and T cell epitopes.
Sandeep Kumar Dhanda, Swapnil Mahajan, S. Paul, Zhen Yan, Haeuk Kim, M. C. Jespersen, V. Jurtz, M. Andreatta, J. Greenbaum, P. Marcatili, A. Sette, M. Nielsen, Bjoern Peters   +12 more
semanticscholar   +1 more source