Results 61 to 70 of about 552,242 (397)
Immunotherapy with Allergen Peptides
Allergy, Asthma & Clinical Immunology, 2007 Specific allergen immunotherapy (SIT) is disease-modifying and efficacious. However, the use of whole allergen preparations is associated with frequent allergic adverse events during treatment.
Larché Mark
doaj +1 more source
Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies [PDF]
, 2008 The E3/19K protein of human adenovirus type 2 (Ad2) was the first viral protein shown to interfere with antigen presentation. This 25 kDa transmembrane glycoprotein binds to major histocompatibility complex (MHC) class I molecules in the endoplasmic ...
Ahmed +62 more
core +1 more source
Arthritis & Rheumatism, 1987 Aucun gene HLA seul n'a ete identifie comme conferant un risque de maladie. Distinction et definition des sous-types DR4. Role de la 3eme region hypervariable de DRβ1.
P. Gregersen, J. Silver, R. Winchester
semanticscholar +1 more source
Defining the epichromatin epitope [PDF]
Nucleus, 2017 Epichromatin is identified by immunostaining fixed and permeabilized cells with particular bivalent anti-nucleosome antibodies (mAbs PL2-6 and 1H6). During interphase, epichromatin resides adjacent to the inner nuclear membrane; during mitosis, at the outer surface of mitotic chromosomes.
Travis J. Gould +6 more
openaire +3 more sources
Active Learning Framework for Cost-Effective TCR-Epitope Binding Affinity Prediction [PDF]
arXiv, 2023 T cell receptors (TCRs) are critical components of adaptive immune systems, responsible for responding to threats by recognizing epitope sequences presented on host cell surface. Computational prediction of binding affinity between TCRs and epitope sequences using machine/deep learning has attracted intense attention recently.
arxiv
CD4+ T-cell responses to Epstein-Barr virus nuclear antigen EBNA1 in Chinese populations are highly focused on novel C-terminal domain-derived epitopes [PDF]
, 2006 Epstein-Barr virus nuclear antigen EBNA1, the one viral protein uniformly expressed in nasopharyngeal carcinoma (NPC), represents a prime target for T-cell-based immunotherapy. However, little is known about the EBNA1 epitopes, particularly CD4 epitopes,
Chan, A. T. C. +8 more
core +1 more source
Uncertainty Estimation in SARS-CoV-2 B-cell Epitope Prediction for Vaccine Development [PDF]
arXiv, 2021 B-cell epitopes play a key role in stimulating B-cells, triggering the primary immune response which results in antibody production as well as the establishment of long-term immunity in the form of memory cells. Consequently, being able to accurately predict appropriate linear B-cell epitope regions would pave the way for the development of new protein-
arxiv
The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design
Frontiers in Immunology, 2017 The task of epitope discovery and vaccine design is increasingly reliant on bioinformatics analytic tools and access to depositories of curated data relevant to immune reactions and specific pathogens.
Ward Fleri +6 more
semanticscholar +1 more source
Microbiology Indonesia, 2014 Human papillomavirus (HPV) type 52 is the most prevalent type for causing cervical cancer in Indonesian population. Cervical cancer becomes the most common cancer suffered by Indonesian women.
SONY SUHANDONO +4 more
doaj +1 more source
Computational Design of a Novel VLP-Based Vaccine for Hepatitis B Virus
Frontiers in Immunology, 2020 Hepatitis B virus (HBV) is a global virus responsible for a universal disease burden for millions of people. Various vaccination strategies have been developed using viral vector, nucleic acid, protein, peptide, and virus-like particles (VLPs) to ...
Saeed Mobini +4 more
doaj +1 more source