Results 71 to 80 of about 552,242 (397)
A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes. [PDF]
, 2018 Human botulism is most commonly caused by botulinum neurotoxin (BoNT) serotypes A, B, and E. For this work, we sought to develop a human monoclonal antibody (mAb)-based antitoxin capable of binding and neutralizing multiple subtypes of BoNT/E.
Brown, Jennifer L +11 more
core +2 more sources
Epitope mapping of ORF3a Protein SARS-CoV-2 in Indonesia through computational study
Journal of Tropical Life Science, 2022 In Indonesia, the vaccine for SARS-CoV-2 is still being developed. ORF3a protein of SARS-CoV-2 could be a potential peptide to be used in the vaccine, therapeutic antibodies, and diagnostic kit development. We used the computational approach in designing
Hartiyowidi Yuliawuri +1 more
doaj +1 more source
Epitope mapping using mRNA display and a unidirectional nested deletion library [PDF]
, 2005 In vitro selection targeting an anti-polyhistidine monoclonal antibody was performed using mRNA display with a random, unconstrained 27-mer peptide library.
Ja, William W. +2 more
core +1 more source
Scientific Reports, 2019 Kaposi’s sarcoma-associated herpesvirus (KSHV) responsible for causing Kaposi sarcoma (KS), an opportunistic angioproliferative neoplasm is emerging rapidly. Despite this there is no permanent cure for this disease.
Varun Chauhan +3 more
semanticscholar +1 more source
Population Ecology, EarlyView.In the process of captive breeding and reintroduction of endangered animal species, it is crucial to minimize familial bias in reproductive success during the reintroduction phase to preserve genetic diversity. In this study, we attempted to identify the familial lineage of individuals of the endangered bagrid fish Tachysurus ichikawai born at the ...
Hinano Mizuno +5 more
wiley +1 more source
Frontiers in Immunology, 2023 Bacteria are well known to provide heterologous immunity against viral infections through various mechanisms including the induction of innate trained immunity and adaptive cross-reactive immunity.
Andrés Bodas-Pinedo +5 more
doaj +1 more source
Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes. [PDF]
, 2003 CD8+ class I-restricted cytotoxic T lymphocytes (CTLs) usually incompletely suppress HIV-1 in vivo, and while analogous partial suppression induces antiretroviral drug-resistance mutations, epitope escape mutations are inconsistently observed.
Ali, Ayub +6 more
core
Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. [PDF]
, 2018 Nanoparticles have attracted considerable interest as cancer vaccine delivery vehicles for inducing sufficient CD8+ T cell-mediated immune responses to overcome the low immunogenicity of the tumor microenvironment.
Kim, Tae Il +5 more
core +2 more sources
The immune epitope database (IEDB) 3.0
Nucleic Acids Res., 2014 The IEDB, www.iedb.org, contains information on immune epitopes—the molecular targets of adaptive immune responses—curated from the published literature and submitted by National Institutes of Health funded epitope discovery efforts.
R. Vita +10 more
semanticscholar +1 more source
Population Ecology, EarlyView.In this article, we tested optimal SNP filtering strategies for accurate parentage assignment and pedigree reconstruction for a wild population of red‐spotted masu salmon, Oncorhynchus masou ishikawae. We found that mid‐point filtering in terms of call rate and minor allele frequency performs well for pedigree reconstruction.
Shohei Noda +6 more
wiley +1 more source