Results 31 to 40 of about 4,508 (221)
RNA Biology, 2022 The universal dihydrouridine (D) epitranscriptomic mark results from a reduction of uridine by the Dus family of NADPH-dependent reductases and is typically found within the eponym D-loop of tRNAs.
Olivier Finet +3 more
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RNA Modification and Its Implication in Plant Pathogenic Fungi [PDF]
The Plant Pathology Journal, 2021 Interaction of a pathogen with its host plant requires both flexibility and rapid shift in gene expression programs in response to environmental cues associated with host cells. Recently, a growing volume of data on the diversity and ubiquity of internal
Junhyun Jeon, Song Hee Lee
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Frontiers in Plant Science, 2022 Epitranscriptome constitutes a gene expression checkpoint in all living organisms. Nitrogen is an essential element for plant growth and development that influences gene expression at different levels such as epigenome, transcriptome, proteome, and ...
Francisco Ortigosa +6 more
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Epitranscriptomic regulation of insecticide resistance [PDF]
Science Advances, 2021 A cytochrome P450 that confers insecticide resistance in whitefly is regulated by an epitranscriptomic mechanism.
Xin Yang +17 more
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Genome Biology, 2018 Cells adapt to stress by altering gene expression at multiple levels. Here, we propose a new mechanism regulating stress-dependent gene expression at the level of translation, with coordinated interplay between the tRNA epitranscriptome and biased codon ...
Cheryl Chan +3 more
doaj +1 more source
Current epigenetic aspects the clinical kidney researcher should embrace [PDF]
, 2017 Chronic kidney disease (CKD), affecting 10-12% of the world's adult population, is associated with a considerably elevated risk of serious comorbidities, in particular, premature vascular disease and death.
Ekström, Tomas J. +5 more
core +1 more source
Epitranscriptomic Regulation in Synaptic Plasticity, Aging and Neurodegeneration [PDF]
, 2022 The regulation of synaptic transmission and plasticity is essential for correct brain function, especially for learning and memory, while the weakening of synaptic transmission and loss of plasticity are hallmarks of the decline of cognitive function ...
Castro Hernández, Ricardo
core +1 more source
Molecular Oncology, 2022 N6‐methyladenosine (m6A) and its regulatory proteins have been associated with tumorigenesis in several cancer types. However, knowledge on the mechanistic network related to m6A in bladder cancer (BlCa) is rather limited, requiring further investigation
Catarina Guimarães‐Teixeira +10 more
doaj +1 more source
Spaceflight Activates Autophagy Programs and the Proteasome in Mouse Liver [PDF]
, 2017 Increased oxidative stress is an unavoidable consequence of exposure to the space environment. Our previous studies showed that mice exposed to space for 13.5 days had decreased glutathione levels, suggesting impairments in oxidative defense.
Blaber, Elizabeth A. +2 more
core +3 more sources
Dawn of Epitranscriptomic Medicine [PDF]
Circulation: Genomic and Precision Medicine, 2018 Medicine is at the crossroads of expanding disciplines. Prompt adaptation of medicine to each rapidly advancing research field, bridging bench to bedside, is a key step toward health improvement. Cardiovascular disease still ranks first among the mortality causes in the Western world, indicating a poor adaptation rate of cardiovascular medicine, albeit
Gatsiou A, Stellos K
openaire +3 more sources