Results 121 to 130 of about 2,699 (211)

Epigenetics and epitranscriptomics in temporal patterning of cortical neural progenitor competence

open access: yes, 2018
During embryonic brain development, neural progenitor/stem cells (NPCs) sequentially give rise to different subtypes of neurons and glia via a highly orchestrated process.
Caroline Vissers   +3 more
core   +1 more source

The Role of Long Noncoding RNAs in Modulation of Stress Granules in Cancer

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Stress granules are dynamic cellular structures that arise in response to stress. They play an important role in cancer cell survival by modulating multiple stress responses. Long noncoding RNAs (lncRNAs) have been identified as crucial regulators of stress granule (SG) dynamics, influencing cancer development and treatment resistance. LncRNAs
Nazlı Şevval Menemenli   +1 more
wiley   +1 more source

Decoding GUN1 in plastid‐to‐nucleus signaling: what it doesn't, what it does, and why it matters

open access: yesNew Phytologist, Volume 251, Issue 1, Page 81-88, July 2026.
Publication history of plant GUN1 research. Summary Plastid‐to‐nucleus retrograde signaling coordinates nuclear gene expression with the developmental and physiological state of plastids. GENOMES UNCOUPLED 1 (GUN1), a chloroplast‐localized PPR‐SMR protein, remains a central yet poorly understood component of this network.
Marco Wendler   +2 more
wiley   +1 more source

Epitranscriptomic RNA m6A Modification in Cancer Therapy Resistance: Challenges and Unrealized Opportunities

open access: yesAdvanced Science
Significant advances in the development of new cancer therapies have given rise to multiple novel therapeutic options in chemotherapy, radiotherapy, immunotherapy, and targeted therapies.
Mohammad Burhan Uddin   +2 more
doaj   +1 more source

Disease‐Associated Remodeling of m6A RNA Methylation in Human Interstitial Cells From Fibro‐Calcific Aortic Valves

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Direct RNA sequencing of primary human valvular interstitial cells (VICs) from non‐calcified control and fibro‐calcific aortic stenosis (AS) valves reveals disease‐associated remodeling of m6A RNA methylation. AS‐derived VICs show an overall increase in detected m6A sites, together with transcript‐specific hyper‐ and hypo‐methylation patterns ...
Vincenza Valerio   +6 more
wiley   +1 more source

Intelligence of Matter: Rise of a New Style of Doing Science and Scientific Thinking?

open access: yesSystems
From Galileo’s conviction that the Universe is written in the language of mathematics to the genomic and computational revolutions of the twentieth century, science has long sought to describe nature through external symbolic systems.
Timir Tripathi   +2 more
doaj   +1 more source

Nanopore-m6A-finder, a novel m6A site caller for Nanopore DRS data

open access: yesFrontiers in Genetics
IntroductionN6-methyladenosine (m6A) is a pivotal RNA modification involved in diverse biological and pathological processes. Compared to the m6A detection methods based on second-generation sequencing, Nanopore direct RNA sequencing (DRS) offers the ...
Yuening Yang   +7 more
doaj   +1 more source

Sex-dependent serotonergic signaling across development: molecular mechanisms shaping vulnerability to neurodevelopmental and mental disorders

open access: yesFrontiers in Pharmacology
Psychiatric disorders and several neurodevelopmental conditions, including autism spectrum disorder, display marked sex biases in prevalence, symptom profiles, and treatment response.
Nicolás Palacios-Avendaño   +3 more
doaj   +1 more source

Science of omics: a molecular space odyssey

open access: yes
Experimental Physiology, EarlyView.
Salomé Coppens   +3 more
wiley   +1 more source

Integrative multi-omic profiling of the chronically hypoxic heart: focus on m6A and m6Am epitranscriptomic regulation

open access: yesFrontiers in Cell and Developmental Biology
Reduced oxygen availability is an environmental factor characteristic of high-altitude conditions that plays a critical role in shaping cellular homeostasis and epigenomic regulation.
Marketa Hlavackova   +10 more
doaj   +1 more source

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