Results 121 to 130 of about 5,351 (235)

Network Analysis of Rodent Transcriptomes in Spaceflight [PDF]

Network analysis methods leverage prior knowledge of cellular systems and the statistical and conceptual relationships between analyte measurements to determine gene connectivity.
Costes, Sylvain, Fogle, Homer, Ramachandran, Maya   +2 more
core   +1 more source

3′ RNA Uridylation in Epitranscriptomics, Gene Regulation, and Disease [PDF]

, 2018
Emerging evidence implicates a wide range of post-transcriptional RNA modifications that play crucial roles in fundamental biological processes including regulating gene expression. Collectively, they are known as epitranscriptomics.
John P. Hagan, Julien Balzeau, Miriam R. Menezes   +2 more
core   +1 more source

RNA Modifications and Epitranscriptomics

Genomics, Proteomics & Bioinformatics, 2023
Chengqi Yi, Jianhua Yang
doaj   +1 more source

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro, J. Carballo, M. C. Pasten, C. A. Gallo, E. Albertini, V. Echenique   +5 more
wiley   +1 more source

Nanopore direct RNA sequencing of human transcriptomes reveals the complexity of mRNA modifications and crosstalk between regulatory features

Cell Genomics
Summary: The identification and functional characterization of chemical modifications on an mRNA molecule, in particular N6-methyladenosine (m6A) modification, significantly broadened our understanding of RNA function and regulation.
Yerin Kim, Luke Saville, Kieran O’Neill, Jean-Michel Garant, Yilin Liu, Simon Haile-Merhu, Maryam Ghashghaei, Quang Anh Hoang, Amber Louwagie, Yongjin P. Park, Steven J.M. Jones, Ly P. Vu   +11 more
doaj   +1 more source

Unveiling RNA Editing by ADAR and APOBEC Protein Gene Families

Frontiers in Bioscience-Landmark
RNA editing is a crucial post-transcriptional modification that alters the transcriptome and proteome and affects many cellular processes, including splicing, microRNA specificity, stability of RNA molecules, and protein structure.
Alexander Modestov, Anton Buzdin, Maria Suntsova   +2 more
doaj   +1 more source

REDIportal: toward an integrated view of the A-to-I editing [PDF]

A-to-I RNA editing is the most common non-transient epitranscriptome modification. It plays several roles in human physiology and has been linked to several disorders.
Cohen-Fultheim, Roni, D'Addabbo, Pietro, Eisenberg, Eli, Fonzino, Adriano, Green, Andrew, Levanon, Erez Y, Luo, Jie, Lussi, Yvonne, Martin, Maria-Jesus, Mazzacuva, Pietro Luca, Pesole, Graziano, Picardi, Ernesto, Prakash, Ananth, Silvestris, Domenico Alessandro, Sweeney, Blake, Twersky, Itamar, Vizcaino, Juan Antonio, Yates, Andy   +17 more
core   +1 more source

Identification and characterization of novel methyltransferases [PDF]

, 2020
So far 172 different types of nucleic acid modifications had been identified. However, for many RNA and DNA modifications the function(s) and the modifying enzymes (”writers”) are still not known. In my Ph.D.
Ignatova, Valentina
core  

One‐Step and Universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U

Chemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.
One‐step, highly efficient, and scalable synthesis of acp3U phosphoramidite is described, as well as a new alternative synthesis of cmnm5U phosphoramidite from a highly versatile intermediate. Latter could be scaled‐up, split, and aliquots turned simultaneously into cmnm5U, nm5U, and mnm5U.
Ewa Mejdr, Lena Heinickel, Thomas Carell, Ivana Mejdr   +3 more
wiley   +1 more source

International projects [PDF]

, 2022
No abstract ...
University of Aveiro, Research Support Office
core   +1 more source