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Epitranscriptomics and Diseases
2021The role of epitranscriptomics, i.e., RNA base modification, as a component of a “methylome” in disease has emerged as a result of the development of next generation sequencing and other related state-of-art technologies. Epitranscriptomic state is controlled by writing, erasing, and reading methylation, which is mediated by enzymatic reactions.
Masamitsu Konno, Hideshi Ishii
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Epitranscriptomic Mass Spectrometry
Every chemical group that is added to any one of the canonical ribonucleotides in a transcript would create a specific RNA modification. Currently, 170+ RNA modifications have been identified. A specific epitranscriptome refers to all the RNA modifications in a given biological system and is considered to play an important role in the regulations of ...Hongzhou, Wang +3 more
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2022
Several chemical modifications in cellular RNAs have been identified to date. The most common internal modification of eukaryotic RNAs is known as m6A. This modification is able to configure the outcome of gene expression by adjusting RNA decay, translation efficiency, RNA structure and alternative splicing.
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Several chemical modifications in cellular RNAs have been identified to date. The most common internal modification of eukaryotic RNAs is known as m6A. This modification is able to configure the outcome of gene expression by adjusting RNA decay, translation efficiency, RNA structure and alternative splicing.
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Epitranscriptomics Markers Regulate the Infection by RNA Viruses
RNA Technologies, 2021Vassiliki Stamatopoulou +2 more
exaly
Epitranscriptomics in liver disease: Basic concepts and therapeutic potential
Journal of Hepatology, 2020Zhicong Zhao, Rui Su, Jianjun Chen
exaly
Epitranscriptomics: A New Layer of microRNA Regulation in Cancer
Cancers, 2021Veronica De Paolis +2 more
exaly
Emerging Role of Epitranscriptomics in Diabetes Mellitus and Its Complications
Frontiers in Endocrinology, 2022Xinqian Geng
exaly
The IGF2BP family of RNA binding proteins links epitranscriptomics to cancer
Seminars in Cancer Biology, 2022Sonia Guil
exaly

