Results 51 to 60 of about 14,736 (216)
Femtoliter Injection of ESCRT-III Proteins into Adhered Giant Unilamellar Vesicles
Bio-Protocol, 2022 The endosomal sorting complex required for transport (ESCRT) machinery mediates membrane fission reactions that exhibit a different topology from that observed in clathrin-coated vesicles.
Vasil Georgiev +3 more
doaj +1 more source
Journal of Cell Biology, 2011 ![Figure][1] More intralumenal vesicles (red) break away from the endosome membrane in control cells (left) than in cells that overexpress a domain of Bro1 (right). The protein Bro1 lives up to its name, [Wemmer et al.][2] show.
openaire +1 more source
Regulation of Vps4 ATPase activity by ESCRT-III [PDF]
Biochemical Society Transactions, 2009 MVB (multivesicular body) formation occurs when the limiting membrane of an endosome invaginates into the intraluminal space and buds into the lumen, bringing with it a subset of transmembrane cargoes. Exvagination of the endosomal membrane from the cytosol is topologically similar to the budding of retroviral particles and cytokinesis, wherein ...
Brian A, Davies +2 more
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LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells [PDF]
, 2016 Endosomal sorting complexes required for transport III (ESCRT-III) proteins have been implicated in sealing the nuclear envelope in mammals, spindle pole body dynamics in fission yeast, and surveillance of defective nuclear pore complexes in budding ...
Bjorkman, Pamela J. +10 more
core +1 more source
CC2D1A Is a Regulator of ESCRT-III CHMP4B [PDF]
Journal of Molecular Biology, 2012 Endosomal sorting complexes required for transport (ESCRTs) regulate diverse processes ranging from receptor sorting at endosomes to distinct steps in cell division and budding of some enveloped viruses. Common to all processes is the membrane recruitment of ESCRT-III that leads to membrane fission.
Martinelli, Nicolas +9 more
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ESCRT-III gets the bends [PDF]
Journal of Cell Biology, 2014 ![Figure][1] The Vps32 subunits in the ESCRT-III complex naturally assemble into spirals. Shen et al. reveal how a key portion of the membrane-snipping ESCRT-III complex gets in shape.
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ESCRT-III Protein Requirements for HIV-1 Budding [PDF]
Cell Host & Microbe, 2011 Two early-acting components of the cellular ESCRT pathway, ESCRT-I and ALIX, participate directly in HIV-1 budding. The membrane fission activities of ESCRT-III subunits are also presumably required, but humans express 11 different CHMP/ESCRT-III proteins whose functional contributions are not yet clear.
Morita, Eiji +5 more
openaire +2 more sources
eLife, 2017 The ESCRT machinery mediates reverse membrane scission. By quantitative fluorescence lattice light-sheet microscopy, we have shown that ESCRT-III subunits polymerize rapidly on yeast endosomes, together with the recruitment of at least two Vps4 hexamers.
Manuel Alonso Y Adell +15 more
doaj +1 more source
Hydraulic fracturing in cells and tissues: fracking meets cell biology [PDF]
, 2017 The animal body is fundamentally made of water. A small fraction of this water is freely flowing in blood and lymph, but most of it is trapped in hydrogels such as the extracellular matrix (ECM), the cytoskeleton, and chromatin.
Arroyo Balaguer, Marino +1 more
core +4 more sources
CK2 involvement in ESCRT-III complex phosphorylation
Archives of Biochemistry and Biophysics, 2014 The multivesicular body (MVB) sorting pathway is a mechanism for delivering transmembrane proteins into the lumen of the lysosome for degradation. ESCRT-III is the final complex in the pathway that assembles on endosomes and executes membrane scission of intraluminal vesicles.
SALVI, MAURO +5 more
openaire +3 more sources