Results 41 to 50 of about 25,445 (232)

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Molecular Genetic Typing of Staphylococcus aureus from Cows, Goats, Sheep, Rabbits and Chickens [PDF]

open access: yes, 2006
End of project reportsS. aureus can also cause a number of infections in animals such as tick-associated pyaemia in lambs, staphylococcosis in rabbits, septicaemia, abscesses and chondronecrosis in chickens and pneumonia and osteomyelitis complex in ...
Hartigan, Patrick J.   +3 more
core  

In-Vivo Expression Profiling of Pseudomonas aeruginosa Infections Reveals Niche-Specific and Strain-Independent Transcriptional Programs [PDF]

open access: yes, 2011
Pseudomonas aeruginosa is a threatening, opportunistic pathogen causing disease in immunocompromised individuals. The hallmark of P. aeruginosa virulence is its multi-factorial and combinatorial nature.
Bielecki, Piotr   +9 more
core   +1 more source

Cell membrane‐coated nanoparticles for dermatological diseases

open access: yesVIEW, EarlyView.
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley   +1 more source

Active immunization using exotoxin A confers protection against Pseudomonas aeruginosa infection in a mouse burn model

open access: yesBMC Microbiology, 2009
Background Pseudomonas aeruginosa is an important cause of nosocomial infection and may lead to septicemia and death. We evaluated the immunogenicity of semi-purified exotoxin A from the bacterium in a mouse burn model.
Naghmachi Mohsen   +7 more
doaj   +1 more source

Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3 - Implications for the evolution of staphylococcal pathogenicity islands [PDF]

open access: yes, 2002
We describe the complete sequence of the 15.9-kb staphylococcal pathogenicity island 3 encoding staphylococcal enterotoxin serotypes B, K, and Q. The island, which meets the generally accepted definition of pathogenicity islands, contains 24 open reading
Kapur, Vivek   +5 more
core  

Localized Periodontitis in Young Individuals: Aggregatibacter JP2 Clone, Immunological Dysfunctions and Other Stories

open access: yesJournal of Periodontal Research, EarlyView.
This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali   +3 more
wiley   +1 more source

14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface

open access: yesNature Communications, 2018
The cellular toxicity of Pseudomonas exotoxin-S and -T depends on their activation by 14-3-3 but the underlying molecular mechanism is not fully understood.
Tobias Karlberg   +16 more
doaj   +1 more source

Towards Engineering Novel PE-Based Immunotoxins by Targeting Them to the Nucleus

open access: yesToxins, 2016
Exotoxin A (PE) from Pseudomonas aeruginosa is a bacterial ADP-ribosyltransferase, which can permanently inhibit translation in the attacked cells. Consequently, this toxin is frequently used in immunotoxins for targeted cancer therapies.
Marta Borowiec   +9 more
doaj   +1 more source

Population Genomics of emm4 Group A Streptococcus Reveals Progressive Replacement with a Hypervirulent Clone in North America

open access: yesmSystems, 2021
Clonal replacement is a major driver for changes in bacterial disease epidemiology. Recently, it has been proposed that episodic emergence of novel, hypervirulent clones of group A Streptococcus (GAS) results from acquisition of a 36-kb DNA region ...
Sruti DebRoy   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy