Results 21 to 30 of about 1,169,724 (211)

Functional Analysis of in Vivo and in Organello Footprinting of HeLa Cell Mitochondrial DNA in Relationship to ATP and Ethidium Bromide Effects on Transcription [PDF]

, 1997
In vivo and in organello footprinting techniques based on methylation interference have been utilized to investigate protein-DNA interactions in the transcription initiation and rDNA transcription termination regions of human mitochondrial DNA (mtDNA) in
Attardi, Giuseppe, Fernádez-Silva, Patricio, Micol, Vicente   +2 more
core   +1 more source

The pathogen Moniliophthora perniciosa promotes differential proteomic modulation of cacao genotypes with contrasting resistance to witches´ broom disease [PDF]

, 2020
Background: Witches' broom disease (WBD) of cacao (Theobroma cacao L.), caused by Moniliophthora perniciosa, is the most important limiting factor for the cacao production in Brazil.
Correa, Stephany Cristiane, Cruz dos Santos, Everton, Gramacho, Karina Peres, Micheli, Fabienne, Pirovani, Carlos Priminho   +4 more
core   +1 more source

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]

, 2016
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P., Chen, Fen, Chen, Shi Y, Fu, Jian F, Shan, Yu J, Wang, An S, Yao, An J, Zhang, Hui Q, Zhang, Xiao H, Zhao, Jin S, Zhou, Zu Q   +10 more
core   +1 more source

Measurements of complement factor H-related protein (BTA-TRAK (TM) assay) and nuclear matrix protein (NMP22 assay) - Useful diagnostic tools in the diagnosis of urinary bladder cancer? [PDF]

, 2003
Between 1997 and 2000 we investigated in a prospective study the voided urine samples of all consecutive patients undergoing cystoscopy independent from their clinical background (n=705) with the BTA-TRAK(TM) assay (Bard Diagnostics, Redmont, USA ...
Hofmann, Karin, Holdenrieder, Stefan, Kriegmair, Martin, Mahnert, Brigitte, Nagel, Dorothea, Reiter, Wolfgang, Schmeller, Nikolaus, Stieber, Petra, Tauber, Stephan   +8 more
core   +1 more source

High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B

Frontiers in Immunology, 2018
Dysregulation of the complement alternative pathway (AP) is a major pathogenic mechanism in atypical hemolytic-uremic syndrome (aHUS). Genetic or acquired defects in factor H (FH), the main AP regulator, are major aHUS drivers that associate with a poor ...
Richard B. Pouw, Richard B. Pouw, Irene Gómez Delgado, Alberto López Lera, Santiago Rodríguez de Córdoba, Diana Wouters, Taco W. Kuijpers, Taco W. Kuijpers, Pilar Sánchez-Corral   +8 more
doaj   +1 more source

A biological, latent variable model of health (EarlyBird 68). [PDF]

, 2014
OBJECTIVE: To determine whether factor analysis of a set of health-related biomarkers provides evidence of an underlying common dimension of variation, and to explore the relationship between this dimension of variation with positive and negative affect.
Hyland, ME, Jeffery, AN, Wilkin, TJ
core   +2 more sources

Human Mas-related G protein-coupled receptors-X1 induce chemokine receptor 2 expression in rat dorsal root ganglia neurons and release of chemokine ligand 2 from the human LAD-2 mast cell line [PDF]

, 2013
Primate-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are highly enriched in dorsal root ganglia (DRG) neurons and induce acute pain. Herein, we analyzed effects of MRGPR-X1 on serum response factors (SRF) or nuclear factors of activated
A Breit, A Romero, A Serrano, A Strasser, AA Genazzani, AJ Shaywitz, Andreas Breit, AS Kirshenbaum, B Fioravanti, B Knoll, B Zimmerman, BD Hudson, C Abbadie, C Gaudioso, CH Wang, DA Taylor, DB Wainscott, E Bullitt, E Grazzini, E Utreras, EJ Vallender, ES Burstein, F Jow, FA White, FA White, Franziska Petermann, G Buchwalter, G Kendall, GA Jamieson Jr, H Chen, H Jung, H Jung, H Subramanian, Hans Jürgen Solinski, HB McIlvain, HJ Solinski, Ingrid Boekhoff, J Li, JG Jackson, JH Sun, JJ Moore Jr, K Rothe, K Tatemoto, Kathrin Rothe, KL Pierce, L Hao, L Jenkins, LM Boland, M Brinkmann, N Eijkelkamp, N Katayama, N Kerr, OM Andrisani, P Kunapuli, P Sikand, PC Francel, PM Lembo, PS Puttfarcken, R Maldonado, RD Groth, RD Groth, RJ Davis, Roland Seifert, S Bhangoo, S Dolan, SF Fan, SK Bhangoo, SN Fatakia, SW Ko, Thomas Gudermann, V Baubet, VS Seybold, X Dong, Y Li   +73 more
core   +12 more sources

Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients [PDF]

, 2017
Objective To characterize, among European and Han Chinese populations, the genetic predictors of maculopapular exanthema (MPE), a cutaneous adverse drug reaction common to antiepileptic drugs.
Auce, Pauls, Avbersek, Andreja, Baum, Larry, Becker, Felicitas, Brodie, Martin J., Canadian Pharmacogenomics Network for Drug Safety, Carleton, Bruce C., Cavalleri, Gianpiero L., Cendes, Fernando, Cherny, Stacey, Coppola, Antonietta, Delanty, Norman, Depondt, Chantal, EPIGEN Consortium, EpiPGX Consortium, Francis, Ben, Gudmundsson, Lárus J., Gui, Hongsheng, Heggeli, Kristin, Ingason, Andrés, International League Against Epilepsy Consortium on Complex Epil, Johnson, Michael R., Klein, Karl Martin, Koeleman, Bobby P.C., Krause, Roland, Krenn, Martin, Kunz, Wolfram S., Kwan, Patrick, Kwok, Maxwell, Langley, Sarah R., Lerche, Holger, Leu, Costin, Liao, Wei-ping, Lopes-Cendes, Iscia, Marson, Anthony G., McCormack, Mark, O'Brien, Terence J., Pirmohamed, Munir, Rau, Sarah, Ross, Colin J.D, Sander, Josemir W., Secolin, Rodrigo, Shear, Neil, Sills, Graeme J., Sisodiya, Sanjay M., Speed, Doug, Stefánsson, Kári, Striano, Pasquale, Weckhuysen, Sarah, Wolking, Stefan, Wright, Galen E.B., Yasuda, Clarissa, Zara, Federico, Zhang, Eunice J.   +53 more
core   +7 more sources

Catastrophic antiphospholipid syndrome accompanied by complement regulatory gene mutation

The Turkish Journal of Pediatrics, 2023
Background. Antiphospholipid syndrome (APS), particularly the catastrophic antiphospholipid syndrome (CAPS), is one of the rare causes of thrombotic microangiopathy (TMA).
Serim Pul, Betül Sözeri, Cemile Pehlivanoğlu, Deniz Filinte, Özde Nisa Türkkan, Mehtap Sak, Neslihan Çiçek, Serçin Güven, Ece Demirci Bodur, İbrahim Gökçe, Harika Alpay   +10 more
doaj   +1 more source

Hypoglycemia-induced changes in complement pathways in type 2 diabetes

Atherosclerosis Plus, 2021
Background and aims: An association between hypoglycaemia and adverse cardiovascular events has been suggested from longitudinal and retrospective cohort studies. The complement pathway proteins in hypoglycemia are not well studied. Here, we hypothesized
Abu Saleh Md Moin, Manjula Nandakumar, Ilhame Diboun, Ahmed Al-Qaissi, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler   +6 more
doaj   +1 more source