Results 251 to 260 of about 2,205,533 (300)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Transgene-Free Direct Osteogenic Reprogramming Using Cell-Permeable Octamer-Binding Transcription Factor 4/Core-Binding Factor β Fusion Proteins. [PDF]

Biomater Res
Kim M, Lee J, Kim W, Kim S, Park J, Park JH.   +5 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Genome-wide identification and expression analysis of Trehalose 6-phosphate (Tre6P) synthase (TPS) and Tre6P phosphatase (TPP) genes under cold stress in winter Rye (Secale cereals L.). [PDF]

BMC Genomics
Wang D, Ren W, Wang X.
europepmc   +1 more source

<i>SHORT INTERNODE (SHI)-Related Sequence</i> Genes in Bread Wheat: Molecular Characterization and Expression Analyses Suggest Their Role in Abiotic Stress Response. [PDF]

Int J Mol Sci
Dudhagi SS, Pathak G, Sharma Y, Verma PC, Singh J, Upadhyay SK.   +5 more
europepmc   +1 more source

Impairment of Macrophage Functions by the Senescence-Associated Secretory Phenotype of Vascular Smooth Muscle Cells-Brief Report. [PDF]

Arterioscler Thromb Vasc Biol
Tsitsipatis D, Rodriguez Rivera T, Kaileh M, Okereke AN, Gupta A, Singh A, Raph SM, Henry-Smith C, Herman AB.   +8 more
europepmc   +1 more source

Craniofacial Fracture and Secretome: A Systematic Review. [PDF]

Plast Reconstr Surg Glob Open
Oley MH, Oley MC, Suoth SC, Yong H, Faruk M, Sukarno V, Gunawan DF.   +6 more
europepmc   +1 more source

Targeting Ferroptosis and Necroptosis to Treat Stroke. [PDF]

Neurochem Res
Sandra Monserrat BP, Carlos Alfredo SI, Rosina ST, Alejandra F, Diana BO, Perla D M.   +5 more
europepmc   +1 more source

Genome-wide identification of the GRAS transcription factor family and regulation of metabolites under drought and salt stress in Isatis indigotica

Chen J, Zhang K, Li H, Lv Z, Yu Y, Ha D, Liu J, Ma Y, Jiang M.   +8 more
europepmc   +1 more source